Gene Information

Name : pykA (BALH_4181)
Accession : YP_896895.1
Strain : Bacillus thuringiensis Al Hakam
Genome accession: NC_008600
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 4403774 - 4405576 bp
Length : 1803 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGTCGGATATTTGGGAACGGTTTCATAATTTTCGGAGGTGCAATATGCGTAAAACTAAAATTGTATGTACTATAGGTCC
TGCTAGTGAAAGTATTGAAAAATTAGAGCAATTAATCGAAGCGGGTATGAACGTTGCTCGTTTAAACTTCTCTCATGGTA
GCCATGAAGAGCACGGCGCTCGTATTAAAAACATTCGTGAAGCTTCAAAGAAAACTGGTAAAACAGTTGGTATCTTACTT
GATACAAAAGGTCCAGAAATCCGTACTCACGACTTCGTAGACGGACAAGCTGAGCTTGTAACAGGTGCAGAAGTAGTTCT
TTCTACTGAGCAAGTATTAGGTACTGCAGAGAAGTTCTCTGTATCTTATGCTGGTCTTTATGACGATGTAGACCCAGGTT
CTCGCATTCTAATCGATGACGGTCTTATCGAGCTAGAAGTAATCGAAAAAGCTGACGGAAACATCCGTACAAAAGTTCTT
AACAGCGGAACTGTAAAAAATAAAAAAGGTGTTAACGTACCAAACGTAAGCATTAAGCTTCCTGGTATCACTGAAAAAGA
TGTAAAAGATATCATCTTCGGTATCGAGCAAAAAGTTGATTTCATCGCAGCTTCATTCGTACGTAAAGCAGCTGACGTAT
TAGAAATCCGTGAATTATTAGAAGAGCATAACGCTCAATACATCCAAATCGTACCAAAAATTGAAAACCAAGAGGGTATC
GACAACATCGATTCAATCTTAGAAGTTTCTGACGGTTTAATGGTAGCTCGTGGTGACATGGGTGTAGAAATTCCGCCAGA
AGAAGTACCATTAGTACAAAAACGTCTAATCAAAAAATGTAACGTGTTAGGTAAACCAGTTATTACTGCAACACAAATGT
TAGATTCTATGCAACGTAACCCACGTCCAACTCGTGCGGAAGCAAGTGACGTAGCTAACGCAATCTTCGATGGTACAGAT
GCAATCATGCTTTCAGGTGAAACGGCTGCTGGACAATACCCAGTAGAAGCAGTAACAATGATGGCTAATATTGCAGTACG
TGTTGAAAAATCATTACAATATGAAGATATGTTCAAAAAACGTATTAAAGAGTTCACTCCAACAATTACAGATGCAATTA
GCCAATCTGTTGCGCATACAGCACTTGCTCTTGATGTAGCTGCAATCGTAGCTCCAACAGAAAGTGGATATACTGCGAAA
ATGATCTCTAAATACCGTCCAAAATCTCCAATCGTAGCTGTAACATCTGACGAGCAAGTAGGACGTCGTCTTGCGCTTGT
TTGGGGTGTACAAGCATTTATGGCTGAGAAGCGTGCGGCTTCTACTGACGAAATGTTAGATACAGCGATTCAAACAGGTA
TGGATGCAGGTCTAATCGGACTTGGAGACACTGTAGTAATCACTGCTGGTGTTCCAGTTGCTGAAACTGGTACAACAAAC
TTAATGAAAATCCACGTTGTTGGTGAAGAAGTTGCTAAAGGACAAGGAATCGGTCGTAAAGCTGCAAAAGGTAAAGTAGT
TGTAGCGAAAACAGCTGCTGAAGCTGTAGCGAACGTAAACGAAGGTGATATCCTTGTTACAACAAGCACTGATAAAGATA
TGATTCCTGCAATCGAAAAAGCTGCTGCTCTAGTTGTAGAAGAAGGCGGCCTAACAAGCCATGCAGCTGTTGTAGGCGTA
TCAATCGGCATTCCTGTTATCGTTGGTGTAAACGGCGTAACAGCAACTTTAAAAAATGGCCAAGAAGTAACAGTTGATGC
AGCACGCGGAATTGTTTATAATGGACATGCGGAAGTGCTATAA

Protein sequence :
MSDIWERFHNFRRCNMRKTKIVCTIGPASESIEKLEQLIEAGMNVARLNFSHGSHEEHGARIKNIREASKKTGKTVGILL
DTKGPEIRTHDFVDGQAELVTGAEVVLSTEQVLGTAEKFSVSYAGLYDDVDPGSRILIDDGLIELEVIEKADGNIRTKVL
NSGTVKNKKGVNVPNVSIKLPGITEKDVKDIIFGIEQKVDFIAASFVRKAADVLEIRELLEEHNAQYIQIVPKIENQEGI
DNIDSILEVSDGLMVARGDMGVEIPPEEVPLVQKRLIKKCNVLGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTD
AIMLSGETAAGQYPVEAVTMMANIAVRVEKSLQYEDMFKKRIKEFTPTITDAISQSVAHTALALDVAAIVAPTESGYTAK
MISKYRPKSPIVAVTSDEQVGRRLALVWGVQAFMAEKRAASTDEMLDTAIQTGMDAGLIGLGDTVVITAGVPVAETGTTN
LMKIHVVGEEVAKGQGIGRKAAKGKVVVAKTAAEAVANVNEGDILVTTSTDKDMIPAIEKAAALVVEEGGLTSHAAVVGV
SIGIPVIVGVNGVTATLKNGQEVTVDAARGIVYNGHAEVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-98 50
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-98 50
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-97 50
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-97 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA YP_896895.1 pyruvate kinase VFG0479 Protein 3e-98 50