Gene Information

Name : metC (BALH_3852)
Accession : YP_896583.1
Strain : Bacillus thuringiensis Al Hakam
Genome accession: NC_008600
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.47
Position : 4061413 - 4062642 bp
Length : 1230 bp
Strand : +
Note : catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity

DNA sequence :
GTGAAAAATTTGACAGATGAGAAGAAGACTCTATTCAAACCGAAAGCCTTCTTCTTAGAAGGCTTTTTTTATTTTATATT
CAACTACTGGTTCAATTTAAAAAGGAGGAATTTTTACATGTCAACTATCGAAACAAAACTAGCGCAAATCGGAAACCGGA
GTGAAACTACAACAGGAACTGTTAATCCGCCTGTTTACTTTTCAACTGCTTATCGTCACGAAGGAATTGGTAAATCTACT
GGATTTGACTATTCACGAACTGGAAATCCAACTCGCGGCCTATTAGAACAGGCAATCGCAGACTTAGAATACGGCGAACA
AGGTTATGCCTGTAGTTCCGGTATGGCATCTGTGCTCCTTGTCCTTTCCCTATTCCGCTCTGGAGACGAACTTATTGTAT
CCGAAGATTTATACGGGGGCACTTATCGATTATTTTCTGAGCACGAAAAAAAGTGGAATGTTCGATGTAGATACGTAAAT
ACACAATCTATTAAACAAATTGAGCAAGCTATCACAACTGAAACGAAAGCTATTTTCATAGAAACCCCGACAAATCCATT
AATGCAAGTTACTGATATTGCCGCTGTCGCAACTGTAGCAAAAAGACACGGACTACTTCTTATTGTAGACAACACATTCT
ACACGCCTTATATACAGCAGCCATTAACAGAAGGTGCTGACATTGTACTTCATAGCGCAACAAAATATTTAGGAGGACAT
AACGATGTACTAAGCGGACTTGTCGTTGCAAAAGGAAAGGAACTTTGTGAGGAAATCGCCCATTATCATAATGCATCAGG
TGCGGTCTTAAGTCCATTTGACTCATGGCTATTAATCCGTGGTATGAAAACGTTAGCGCTTCGCATGAGACAACATGAAG
AAAATGCAAAAGCAGTTGTTGCTTATTTAAATGATGAGGACGGGGTGACAGATGTATTTTATCCTGGAAGAGGCGGCATG
ATCTCATTTCGTCTTAAAGATGAAACATGGATTAATCCATTCTTACAATCTTTATCCTTAATTACATTCGCCGAAAGTCT
TGGTGGTGTTGAAAGTTTAATGACATATCCAGCAACACAAACACACGCTGATATTCCTGAAGAAATCAGAACAGCAAACG
GTGTATGTAATCGTCTTCTTCGATTTTCTGTTGGCATTGAAAATAGTAACGATTTAATTCAAGACTTACAGCAAGCCATT
AAACTTGTAAAAGAAGGTGTAAGAATATGA

Protein sequence :
MKNLTDEKKTLFKPKAFFLEGFFYFIFNYWFNLKRRNFYMSTIETKLAQIGNRSETTTGTVNPPVYFSTAYRHEGIGKST
GFDYSRTGNPTRGLLEQAIADLEYGEQGYACSSGMASVLLVLSLFRSGDELIVSEDLYGGTYRLFSEHEKKWNVRCRYVN
TQSIKQIEQAITTETKAIFIETPTNPLMQVTDIAAVATVAKRHGLLLIVDNTFYTPYIQQPLTEGADIVLHSATKYLGGH
NDVLSGLVVAKGKELCEEIAHYHNASGAVLSPFDSWLLIRGMKTLALRMRQHEENAKAVVAYLNDEDGVTDVFYPGRGGM
ISFRLKDETWINPFLQSLSLITFAESLGGVESLMTYPATQTHADIPEEIRTANGVCNRLLRFSVGIENSNDLIQDLQQAI
KLVKEGVRI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-72 45
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-73 45