Gene Information

Name : guaA (CFF8240_1264)
Accession : YP_892420.1
Strain : Campylobacter fetus 82-40
Genome accession: NC_008599
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1254465 - 1255997 bp
Length : 1533 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAAAAATGCAGATATATTGGTTCTAGACTTTGGATCACAATACACTCAACTTATCGCTAGAAGGCTTAGAGAGCAAGG
CGTTTATGCTGAGCTTATGCCTTTTAATGTAAGCATCGAAGCTATAAAAGCAAAAAATCCAAAAGGTATTATTTTAAGCG
GCGGACCAGCTAGCGTGTATGCAAAAGATGCGTATTTTTGCGATGAAGGCGTATTTACTTTAGGACTTCCGGTTCTTGGA
ATTTGTTATGGAATGCAGCTTTTAGCGCATAAAAATGGAGCAGACGTAGCTCCAGCAGGTCATAAAGAGTATGGGAAAGC
AAATTTAAATATAGTTAAAAAGTGCGATTTTTTTAAAGGAGTTCCAGATACAAGTGTTGTGTGGATGAGTCATTCTGATA
AAGTAAATGAACTTCCGCAAGGTTTTGAAGTATTAGCAAATTCGGAAAATAGCGAGTTTTGCGTATTTGCAAATTTAGAT
AAAAAACTCTATGCTTTGCAATTTCATCCAGAAGTTGCTCACTCTGAGTTCGGTGATACTATGCTTAAAAATTTTGCTAA
AATTTGTGGATGCGAAAGTACTTGGAATATGGGAAGTTTTGCAAAAAAAGAGGTTCAAGCTATCCGTGAAAAAGTAGGAA
ACGACAAGGTTTTATGCGCAGTAAGTGGCGGTGTCGATAGCTCTGTTGTAGCCGCGCTTTTAGCTCACGCGATACCGGAT
AATTTAATAGTAGTTTTTGTAGATAACGGTCTTCTTAGAACAAACGAAGCAAAGCAAGTTGAAGAGATGTTTAAGCTAAA
ATTAGGAGTAAATTTAATAAGCATAGATGCAAGCGAGCTATTTCTAAGTAGATTAAAAGGTGTAAGAGATCCTGAGAAAA
AGCGTAAAATTATAGGTGAGACTTTTATAGAGGTGTTTGATAAAGAGGCAAAAAAACACTCTAATGTAAAATACCTTGCC
CAGGGTACTTTATACACGGATGTTATAGAAAGCAGTGTTGTAGGATCTAGTAAAACTATAAAAAGCCATCATAATGTAGG
CGGACTTCCTGAGTGGATGGAATTTGAACTAATCGAACCTTTAAGAGAAATTTTTAAAGATGAAGTAAGACGTCTTGGAC
TTGAGTTAGGACTTAGTAGAGATATAGTTTATCGTCATCCTTTTCCGGGTCCAGGGCTTGCTATACGCATTATGGGAGAG
GTAAATACTTCTAGTTTGGAGCTTCTTAGAAAGGCTGATGTAATACTAAGAGAAGAGTTGAAAAGCAGCGGCTGGTACGA
TAAAACTTGGCAAGCATTTTGTGTACTTCTAAATGTAAATTCAGTCGGAGTTATGGGAGATAATAGAACATACGAAAACG
CAGTTTGCTTAAGAGTGGTGGATGCAAGCGATGGCATGACGGCAAGTTTTTCTAGGCTTCCGTATGATCTGTTGGAAAAT
TGCAGCCGCCGCATTATAAATGAAGTCGATGGCATAAACCGCGTAGTTTATGATATCAGCTCAAAACCGCCAGCAACTAT
AGAGTGGGAATAG

Protein sequence :
MKNADILVLDFGSQYTQLIARRLREQGVYAELMPFNVSIEAIKAKNPKGIILSGGPASVYAKDAYFCDEGVFTLGLPVLG
ICYGMQLLAHKNGADVAPAGHKEYGKANLNIVKKCDFFKGVPDTSVVWMSHSDKVNELPQGFEVLANSENSEFCVFANLD
KKLYALQFHPEVAHSEFGDTMLKNFAKICGCESTWNMGSFAKKEVQAIREKVGNDKVLCAVSGGVDSSVVAALLAHAIPD
NLIVVFVDNGLLRTNEAKQVEEMFKLKLGVNLISIDASELFLSRLKGVRDPEKKRKIIGETFIEVFDKEAKKHSNVKYLA
QGTLYTDVIESSVVGSSKTIKSHHNVGGLPEWMEFELIEPLREIFKDEVRRLGLELGLSRDIVYRHPFPGPGLAIRIMGE
VNTSSLELLRKADVILREELKSSGWYDKTWQAFCVLLNVNSVGVMGDNRTYENAVCLRVVDASDGMTASFSRLPYDLLEN
CSRRIINEVDGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-138 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-139 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-139 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-116 50