Gene Information

Name : lysS (CFF8240_1142)
Accession : YP_892300.1
Strain : Campylobacter fetus 82-40
Genome accession: NC_008599
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1133004 - 1134518 bp
Length : 1515 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGATATTTGAAAATGAATTAGAATTAACAAGGTTAGCTAAAGCAGATGAGCTTAGAAGCTTAGGAGTAAATCCATATCC
TCACTTTTTAAAACGCGATATGAGTATTAGCGAGTTTAAAACCAAATTTGCCTATATCAAAGATTTAAATGGCGATGAAA
AAAAAGCAGATGAAGAAGTAACTATTTCAGGGCGTTTGAAACTAAAAAGGGTGGCCGGAAAATCTACTTTTGCAAATATG
GAAGATGAAAATGATAATATTCAAATTTACTACTCTTTAGGCAGTATAGGCGAAGAAGATTATACTAAATTTAAAAAAAA
TCTGGAAGTCGGAGATATAGTATTAGTCACCGGATACGCGTTTGTAACAAAAACCGGTGAGTTTAGTATCCATGCAAGTA
AAATAGTATTAGCTAGTAAAGCTATCAGTCCTCTTCCAGAGAAGTTTCACGGTCTTACCGATATCGAGATGAGATATCGT
CAAAGATATCTTGATATGATAATGGATAAAGATGTTAGAGCCGATTTCGTAAAACGCTCACTTATAATAAGCACTATTCG
AAGATTTTTTGAAGATAAAGGCTTTTTGGAAGTTGAAACTCCTATGATGCATCCGATAGCTGGCGGGGCAAACGCAAAGC
CGTTTATCACTCACCATAACGCACTAGATGTGGATAGGTATTTGAAAATCGCTCCGGAGTTATATCTAAAAAGACTTATT
GTAGGTGGTATGGAAGCCGTGTTTGAGATGAATAGATGTTTCAGAAATGAAGGAATGGACCTTACTCATAATCCGGAATT
TACAAGCATTGAGTTTTACTGGGCATGGCATAATTATTTTGAAGCAATGGATTTAACTGAAGAGTTATTTGCTGTTTTAT
TAGATAGATTAAATTTACCACAAGTTATCGAATTTGATGGTAAAAGTATTGATTTTTCTAAGCCTTTTGCTAGAGTAAAA
TACATAGACGCCATAGTTGAAATCGGTGGTATTAGCAGAGATATAGTTACTAATAAAGATAAAATTTTATCAAAATTAAA
AGCAGATAAATTTGAAGCGAATGATAAGCTGGATCTTGGTCATTTACAAGCTGAACTTTTTGATAATTATGTTGAAGATA
AGCTAATAAATCCAACATTTATAGTGGATTTTCCTATATCTATAAGCCCGCTTTCAAGAAGAAGTGATGCAGATAAAAAT
GTAGCCGAAAGATTTGAGCTGTTCATCGCAGGTCGTGAGTTGGCAAATGCATTTAATGAGTTAAATGATCCAGTTGATCA
GTATGAGAGATTTAAATCCCAAATAGAAGCAAAAAATGCAGGAGATGATGAGGCGCATGAGATGGATGAAGATTATTGTC
AAGCATTAGGCTATGGTATGTCTCCAACCGTAGGATGGGGACTTGGCGTTGATAGGTTAGTAATGCTGCTTCTAAATAAA
AAGTCTATACGAGATGTTATACTTTTTCCTGCTATGAAACCACTAAAAACCGAAAATAAGGAGAATAAAAAATGA

Protein sequence :
MIFENELELTRLAKADELRSLGVNPYPHFLKRDMSISEFKTKFAYIKDLNGDEKKADEEVTISGRLKLKRVAGKSTFANM
EDENDNIQIYYSLGSIGEEDYTKFKKNLEVGDIVLVTGYAFVTKTGEFSIHASKIVLASKAISPLPEKFHGLTDIEMRYR
QRYLDMIMDKDVRADFVKRSLIISTIRRFFEDKGFLEVETPMMHPIAGGANAKPFITHHNALDVDRYLKIAPELYLKRLI
VGGMEAVFEMNRCFRNEGMDLTHNPEFTSIEFYWAWHNYFEAMDLTEELFAVLLDRLNLPQVIEFDGKSIDFSKPFARVK
YIDAIVEIGGISRDIVTNKDKILSKLKADKFEANDKLDLGHLQAELFDNYVEDKLINPTFIVDFPISISPLSRRSDADKN
VAERFELFIAGRELANAFNELNDPVDQYERFKSQIEAKNAGDDEAHEMDEDYCQALGYGMSPTVGWGLGVDRLVMLLLNK
KSIRDVILFPAMKPLKTENKENKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-100 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_892300.1 lysyl-tRNA synthetase VFG1668 Protein 2e-100 45