Gene Information

Name : thiC (MSMEG_0826)
Accession : YP_885230.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_008596
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 911327 - 912901 bp
Length : 1575 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
GTGACGACCGGCCCGATCACGGGGAGTACCAAGGCCTATCGCGAGGTGGAGCATCCGGGGGTGGACGTCCCGCTGCGGGT
GCCGTTCCGCCGGGTCCACCTGAGCGACGGCGACCACCTCGACCTGTACGACACGTCCGGTCCGTACACCGACACCGACG
CCGTCATCGACCTCGACGCGGGCCTGACACCGCGACCCGGGGTGGTGCGCGACCGCGGCACGCAGCTGCAACGCGCCCGT
GCCGGTGAGATCACCGCCGAGATGGCGTTCATCGCCGAGCGCGAAGGCGTCCCCGCCGAACTGGTGCGTTCCGAGGTGGC
ACGTGGGCGGGCGGTGATCCCGGCCAACCACAATCACCCCGAGAGCGAACCGATGATCATCGGCAAGGCCTTCGGCGTGA
AAGTCAATGCGAACATCGGCAATTCGGCGGTCACATCGTCGATCGCCGAAGAAGTCGACAAGATGGTGTGGGCGACCCGC
TGGGGTGCCGACACCATCATGGACCTGTCGACCGGTCGCGACATCCACCTGACGCGGGAATGGATCCTGCGCAACTCGCC
GGTGCCGGTGGGCACCGTGCCCATGTACCAGGCACTGGAGAAGGTCAACGGCGACCCCACCAAGCTCAGCTGGGATGTCT
ACCGCGACACCGTGATCGAGCAGTGCGAACAGGGCGTGGACTACATGACCGTGCACGCCGGTGTGCTGCTGCGGCACATC
CCGCTGACGGTCGACCGGGTCACGGGCATCGTGTCACGCGGCGGGTCGATCATGGCGGCCTGGTGCCTGGCACATCACAC
AGAGTCGTTCCTGTACACCAACTTCGAGGAACTGTGTGAGATCTTCGCACGCTACGACGTGACGTTCTCGCTGGGCGACG
GCCTGCGCCCGGGGTCCATCGCCGACGCCAACGACGCGGCCCAATTCGCCGAACTGCGCACCCTCGGCGAGCTCACCACG
ATCGCGAAAAACCATGGCGTGCAGGTGATGATCGAAGGCCCTGGCCACGTCCCCATGCACAAGATCGTCGAGAACGTGCG
CCTCGAAGAGGAACTGTGTGACGATGCGCCGTTCTACACACTGGGACCGCTCGCGACCGACATCGCCCCGGCGTACGACC
ACATCACCTCGGCGATCGGCGCGGCGATCATCGCCCAGGCAGGCACCGCGATGCTGTGCTACGTCACACCCAAGGAGCAT
CTGGGCCTGCCCAACCGCCAGGACGTCAAGGACGGCGTGATCGCCTACAAGATCGCGGCGCACTCTGCCGACCTGGCCAA
GGGCCATCCCCGCGCGCAACAGCGCGATGACGCACTGTCCAAGGCGCGCTTCGAGTTCCGGTGGCACGACCAGTTCGCGC
TGTCGCTGGATCCCGACACCGCGCGCGAGTTCCACGACGAGACACTGCCCGCCGAACCGGCGAAGACCGCGCACTTCTGC
TCGATGTGCGGGCCCAAGTTCTGCTCCATGCGCATCACGGCCGACCTCAAGGATTCGATCCGCGAGGCGATGGACCAGAA
ATCCGCCGAGTTCGCCGAACAGGGGAACCGTGTGTATCTACCGTTGACATCGTGA

Protein sequence :
MTTGPITGSTKAYREVEHPGVDVPLRVPFRRVHLSDGDHLDLYDTSGPYTDTDAVIDLDAGLTPRPGVVRDRGTQLQRAR
AGEITAEMAFIAEREGVPAELVRSEVARGRAVIPANHNHPESEPMIIGKAFGVKVNANIGNSAVTSSIAEEVDKMVWATR
WGADTIMDLSTGRDIHLTREWILRNSPVPVGTVPMYQALEKVNGDPTKLSWDVYRDTVIEQCEQGVDYMTVHAGVLLRHI
PLTVDRVTGIVSRGGSIMAAWCLAHHTESFLYTNFEELCEIFARYDVTFSLGDGLRPGSIADANDAAQFAELRTLGELTT
IAKNHGVQVMIEGPGHVPMHKIVENVRLEEELCDDAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEH
LGLPNRQDVKDGVIAYKIAAHSADLAKGHPRAQQRDDALSKARFEFRWHDQFALSLDPDTAREFHDETLPAEPAKTAHFC
SMCGPKFCSMRITADLKDSIREAMDQKSAEFAEQGNRVYLPLTS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 6e-153 59
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 6e-153 59