Gene Information

Name : purA (MSMEG_0759)
Accession : YP_885165.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_008596
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 844214 - 845509 bp
Length : 1296 bp
Strand : +
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGCCGGCAATCGTGCTCATCGGGGCCCAATGGGGCGACGAGGGCAAAGGTAAAGCCACCGATCTACTCGGTGGACGCGT
GCAGTGGGTAGTTCGCTACCAGGGCGGCAACAACGCGGGACACACCGTCGTGTTGCCCACCGGGGAGAACTTCGCGCTGC
ACCTCATCCCCTCGGGCATCCTCACACCCGGGGTCACCAACGTCATCGGTAACGGTGTGGTGGTCGACCCGGGCGTGCTG
TTGACCGAGCTGAAGGGCCTCGAGGATCGCGGGGTCGACACGTCGAACCTGCTGATCTCGGCCGACGCCCATCTGCTGAT
GCCGTACCACGTCGCGATCGACAAGGTCGTGGAGCGCTGGGCGGGCAGCAAGAAGATCGGCACCACGGGCCGCGGTATCG
GCCCGTGCTACCAGGACAAGATCGCGCGCATCGGCATCCGGGTGGCCGACGTGCTCGACGAGCAGGTGCTGGCCGAAAAG
ATCGAGGCCGCACTTGAATTCAAGAACCAGGTGCTGGTCAAGATCTACAACCGCAAGGCGCTGGAGCCCGCCGAGGTGCT
CGAGAACCTGCTGGAACAGGCCGAGGGCTTCAAGCATCGCATCGCCGACGCGCGGCTGCTGCTCAACCAGGCGCTGGAGA
ACGACGAGGCCGTGCTGCTCGAGGGCTCGCAGGGCACCCTGCTGGATGTCGACCACGGCACGTATCCCTTTGTCACGTCG
TCGAACCCGACGGCAGGCGGCGCCGCGGTCGGCTCGGGCATCGGGCCCACCCGCATCACCACGGTGCTGGGCATCCTCAA
GGCGTACACCACGCGCGTCGGCTCCGGTCCGTTCCCCACCGAACTGTTCGACGAGCACGGCGCCTACCTGGCCAAGACCG
GTGGCGAGGTCGGTGTCACGACCGGCCGCGCCCGTCGATGCGGCTGGTTCGACGCGGTGATCGCGCGCTACGCGACCAGG
GTCAACGGCATCACCGACTACTTCCTGACCAAGCTCGACGTGCTGTCGAGCCTGGAGACAGTGCCGGTGTGCGTCGGCTA
CACGGTCGACGGCAAGCGTGTCGACGAGATGCCGATGACGCAGTCGGACATCGCCCGCGCCGAGCCCGTCTACGAGGAAC
TGCCGGGCTGGTGGGAGGACATCTCGGGCGCACGCGAGTTCGAGGATCTGCCCGCCAAGGCCCGCGACTACGTGCTGCGC
CTCGAAGAGCTTGCCGGAGCGTATGTTTCGTGCATCGGTGTGGGGCCGGGCCGGGATCAGACCATCGTGCGCCGTGACGT
GCTGGCTGCCCGTTGA

Protein sequence :
MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGENFALHLIPSGILTPGVTNVIGNGVVVDPGVL
LTELKGLEDRGVDTSNLLISADAHLLMPYHVAIDKVVERWAGSKKIGTTGRGIGPCYQDKIARIGIRVADVLDEQVLAEK
IEAALEFKNQVLVKIYNRKALEPAEVLENLLEQAEGFKHRIADARLLLNQALENDEAVLLEGSQGTLLDVDHGTYPFVTS
SNPTAGGAAVGSGIGPTRITTVLGILKAYTTRVGSGPFPTELFDEHGAYLAKTGGEVGVTTGRARRCGWFDAVIARYATR
VNGITDYFLTKLDVLSSLETVPVCVGYTVDGKRVDEMPMTQSDIARAEPVYEELPGWWEDISGAREFEDLPAKARDYVLR
LEELAGAYVSCIGVGPGRDQTIVRRDVLAAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 5e-103 53