Gene Information

Name : MSMEG_0732 (MSMEG_0732)
Accession : YP_885138.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_008596
Putative virulence/resistance : Virulence
Product : chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 817638 - 820184 bp
Length : 2547 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
GTGGACTCGTTCAACCCGACGACCAAGACTCAGGCGGCGCTGACCTCGGCGTTGCAGGCGGCGAGTTCCGCTGGCAACCC
GGAGATCCGCCCCGCGCATTTGCTGATGGCATTGCTGACCCAGAATGACGGCATTGCCGCACCCCTGCTGGAGGCCGTCG
GCGTCGAGCCCGCGACGATCCGCACCGAGACCCAGCGGTTGCTCGACCGTCTGCCCAGCGCCTCGGGCGCGAGCAGCCAG
CCCCAGCTCAGCCGCGAATCGCTCGCGGCGATCACCACGGCCCAGAACCTGGCCACCGAGATGGACGACGAGTACGTCTC
GACCGAGCACCTGATGGTCGGCCTGGCCACGGGTGACTCCGAGGTGGCCAAGCTGCTGACCGGACACGGCGCGTCGCCGC
AGGCTCTGCGTGAGGCGTTCGTCAAGGTGCGCGGCAGCGCCCGGGTGACCAGCCCGGACCCGGAGGGCACGTATCAGGCG
CTGGAGAAGTACTCCACCGACCTGACCGCGCGTGCCCGCGAGGGCAAGCTCGACCCGGTGATCGGGCGCGACAACGAGAT
TCGTCGTGTCGTACAGGTGCTGAGCCGTCGTACCAAGAACAATCCGGTGCTCATCGGCGAGCCGGGCGTCGGTAAGACGG
CCATCGTCGAGGGCCTCGCGCAGCGCATCGTCGCCGGCGACGTGCCCGAAAGCCTGCGCGACAAGACCGTCATCGCACTG
GATCTCGGTTCGATGGTGGCCGGTGCGAAGTACCGCGGTGAGTTCGAGGAGCGGCTGAAGGCCGTGCTCGACGACATCAA
GAACTCGGCCGGGCAGGTCATCACGTTCATCGACGAGCTGCACACCATCGTCGGCGCCGGTGCCACCGGTGAGTCGGCGA
TGGACGCGGGCAACATGATCAAGCCGATGCTGGCCCGCGGCGAGCTGCGGCTGGTCGGTGCCACCACGCTCGACGAGTAC
CGCAAGTACATCGAGAAGGACGCCGCATTGGAGCGCCGGTTCCAGCAGGTGTTCGTCGGTGAACCCTCGGTCGAGGACAC
CGTCGGCATCCTGCGTGGTCTGAAGGACCGCTACGAGGTGCACCACGGCGTGCGGATCACCGACTCGGCGTTGGTGGCCG
CGGCGACGCTCTCCGACCGGTACATCACCGCGCGGTTCCTTCCGGACAAGGCCATCGACCTGGTCGATGAGGCCGCGTCC
CGGCTGCGCATGGAGATCGACTCGCGCCCAGTTGAAATCGACGAGGTCGAGAGGTTGGTACGGCGCCTGGAGATCGAGGA
GATGGCGCTTGAGAAAGAAGAGGACGAGGCGTCCAAGGACCGGCTGGAGAAGCTGCGCGCCGAACTGGCCGACCACAAGG
AGAAGCTGTCCGAGCTGACCACGCGGTGGCAGAACGAGAAGAACGCCATCAACGTCGTTCGCGAGCTCAAGGAGCAACTG
GACACGTTGCGCGGCGAGGCCGACCGTGCCGAGCGTGACGGTGACCTGGCCAAGGCGGCCGAACTGCGGTACGGCCGAAT
CCCGGAGGTGGAGAAGAAGCTCGACGCTGCCCTTCCCGCCGCCGAGGCCCGCGAGAACCTGATGCTCAAGGAGGAGGTCG
GCCCCGACGACATCGCCGAGGTGGTGGAGGCGTGGACCGGTATCCCGTCCGGCCGCATGCTCGAAGGCGAGACCGCCAAG
CTGCTCCGCATGGAGGAGGAGCTGGGCAAGCGTGTCGTCGGGCAGCGCAAGGCCGTGCAGGCCGTCAGCGACGCGGTGCG
GCGCAGCCGTGCCGGGGTGGCCGACCCCAACCGGCCGACGGGTTCGTTCATGTTCCTGGGCCCGACCGGTGTGGGTAAGA
CCGAGCTCGCAAAGGCGTTGGCGGAGTTCTTGTTCGACGACGAGCGTGCGATGGTCCGCATCGACATGAGCGAGTACGGC
GAGAAGCACTCGGTGGCTCGGCTGGTCGGTGCGCCTCCCGGCTACATCGGTTACGACCAGGGCGGTCAGCTGACCGAGGC
GGTGCGGCGGCGTCCGTACACGGTGATCCTGTTCGACGAGATCGAAAAGGCGCACCCGGACGTGTTCGACGTGCTGCTGC
AGGTGCTCGACGAGGGCCGGTTGACCGACGGCCAGGGCCGCACGGTCGACTTCCGCAACACCATCCTCATCCTGACGTCC
AACCTGGGCGCGGGCGGTAACGAGGACCAGGTGATGGCGGCGGTGCGCTCGGCGTTCAAGCCCGAGTTCATCAACCGGCT
GGACGACGTCATCATCTTCGACGGGCTCAATCCCGAAGAGCTGGTGCAGATCGTCGACATCCAGTTGGCGCAGCTGGCCA
AGCGTCTGGAGCAGCGGCGACTCACCCTCGAGGTGTCGCTGCCGGCCAAGAAGTGGCTGGGGCAGCGCGGTTTCGACCCG
CTGTACGGTGCCCGTCCGCTGCGCCGGTTGGTGCAGCAGGCCATCGGCGACCAGTTGGCCAAGATGCTGCTGGCCGGCGA
GGTGCACGACGGCGACATCGTGCCGGTGAACGTCAGCCCCGACGGCGAGTCCCTCGTTTTGGGCTGA

Protein sequence :
MDSFNPTTKTQAALTSALQAASSAGNPEIRPAHLLMALLTQNDGIAAPLLEAVGVEPATIRTETQRLLDRLPSASGASSQ
PQLSRESLAAITTAQNLATEMDDEYVSTEHLMVGLATGDSEVAKLLTGHGASPQALREAFVKVRGSARVTSPDPEGTYQA
LEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTVIAL
DLGSMVAGAKYRGEFEERLKAVLDDIKNSAGQVITFIDELHTIVGAGATGESAMDAGNMIKPMLARGELRLVGATTLDEY
RKYIEKDAALERRFQQVFVGEPSVEDTVGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDLVDEAAS
RLRMEIDSRPVEIDEVERLVRRLEIEEMALEKEEDEASKDRLEKLRAELADHKEKLSELTTRWQNEKNAINVVRELKEQL
DTLRGEADRAERDGDLAKAAELRYGRIPEVEKKLDAALPAAEARENLMLKEEVGPDDIAEVVEAWTGIPSGRMLEGETAK
LLRMEEELGKRVVGQRKAVQAVSDAVRRSRAGVADPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYG
EKHSVARLVGAPPGYIGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQVLDEGRLTDGQGRTVDFRNTILILTS
NLGAGGNEDQVMAAVRSAFKPEFINRLDDVIIFDGLNPEELVQIVDIQLAQLAKRLEQRRLTLEVSLPAKKWLGQRGFDP
LYGARPLRRLVQQAIGDQLAKMLLAGEVHDGDIVPVNVSPDGESLVLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-103 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-103 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MSMEG_0732 YP_885138.1 chaperone ClpB VFG2084 Protein 1e-110 44