Gene Information

Name : MSMEG_6297 (MSMEG_6297)
Accession : YP_890515.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_008596
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 6363136 - 6364671 bp
Length : 1536 bp
Strand : +
Note : identified by match to protein family HMM PF00171

DNA sequence :
ATGACAGTCACCACCTTCCGCCCGTCCGACGTCGCCACCCTCACGAACCCGGACGCCGCCTCCGACGTCGCCGATCTGTC
GATGTTCATTGCCGGAGAGGCGGTTTCCGCTGCCGACGGCGCCACGTTCGACTCCTACGAACCCCGCTCCGGGCGGGTGT
GGGCACGGTTGCCGCGGGCCAATTCGACCGACATCGACCGTGCCGTGCGCGCGGCGCGCGCAGCCTTCGAAGGGCCGTGG
GGCGCTGTGTCGCCCGCCGACCGCGGCCGATTCCTGATGAAGATCGCCGCAGTGGTCGACCGGCACCGGGATCAACTCAC
GGTCATCGAGTCCCGCGACAACGGCAAACCGGTCCGCGAGGTGCGTGCCGAGATCGACGCGGTCGTACGCTATTTCGAGT
ACTTCGCGGGTGTGTGCCAGACGACGGTGGGTGAGACCCATCCCCAGGCGGCCACGGCCTTCAGCTACACCCGCCGCGAA
CCGGTGGGTGTGGTCGGCGCGATCGTGCCCTGGAACTCGCCGCTGCTCATGCTCGCGTGGAAGCTGTCGCCCGCCCTGGC
AGGCGGTAACACCATCATCCTCAAACCCGCCGAGGAGACCTCGGTCTCCGCGGTCGTGTTCGCTCAGCTCATCGCCGAGG
TGGGACTGCCCGACGGAGTCTTCAACGTGGTGACCGGAATCGGCGAGGAAGCCGGCGCCGCGCTGGTCGCCCATCCGGAT
GTCGACAAGATCGCCTTCACCGGTTCGACCGAGGTGGGCAAGCAGATCGCGGCCACCGCGGCAAGCGATCTCAAACTCGT
CACCTTCGAACTGGGCGGCAAGTCACCCACCGTGATCTTCGACGACGCCGACCTCGATGCCGCGGTTCACCGCACCGCTT
ACGGCATCTTCTCGGCCGCGGGTCAGACCTGTCAGGCGGCATCGCGAATCTTCGTCCAGGACACCATCCACGACGAATTC
CTGGACCGGTTCGCCGCACTGGCACGGCGCATCCGCGTGGGCGATCCGCTGTCCGAGCGCACCCAGATGGGCGCCCAGAT
TTCCGCACAGCATCGCGAACGGATCGCCGGGTACGTCGCCAGCGGCATCCAGGAGGGAGCGAATCTGGTCTGCGGCGGCA
CGCAGCCCACGGAAGCCCCGCTGGCGCAGGGCTACTACTACTCGCCGACCATCCTCGACGGCGTCAACCGCGACATGCGG
ATGATCCGCGAGGAGATCTTCGGGCCGGTGACCGGTGTCATGTCATTCACCGACGAGGCCGACGCCGTGGCCAAGGCGAA
TGACACGGAGTACGGCCTGGCCGGATCGGTGTGGACGCGGGACGTGTCCCGCGCGCACCGGGTCGCGGCGAGCATTGCGG
CCGGACTGATCTGGGTCAACACCACCCGCACCATCAACCACCTCGTTCCGTTCGGCGGCTACAAGCAGTCCGGTTACGGG
CGCGAGGGCGGACAGGCCGTGATGGAGCACTACACCCGGATCAAGTCGGTGTGGGTGGACATGCAGGACGACCTGCCGAA
CTGGTACGCCGACTGA

Protein sequence :
MTVTTFRPSDVATLTNPDAASDVADLSMFIAGEAVSAADGATFDSYEPRSGRVWARLPRANSTDIDRAVRAARAAFEGPW
GAVSPADRGRFLMKIAAVVDRHRDQLTVIESRDNGKPVREVRAEIDAVVRYFEYFAGVCQTTVGETHPQAATAFSYTRRE
PVGVVGAIVPWNSPLLMLAWKLSPALAGGNTIILKPAEETSVSAVVFAQLIAEVGLPDGVFNVVTGIGEEAGAALVAHPD
VDKIAFTGSTEVGKQIAATAASDLKLVTFELGGKSPTVIFDDADLDAAVHRTAYGIFSAAGQTCQAASRIFVQDTIHDEF
LDRFAALARRIRVGDPLSERTQMGAQISAQHRERIAGYVASGIQEGANLVCGGTQPTEAPLAQGYYYSPTILDGVNRDMR
MIREEIFGPVTGVMSFTDEADAVAKANDTEYGLAGSVWTRDVSRAHRVAASIAAGLIWVNTTRTINHLVPFGGYKQSGYG
REGGQAVMEHYTRIKSVWVDMQDDLPNWYAD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-86 42
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 4e-83 42
unnamed AAK01506.1 putative aldehyde dehydrogenase Not tested PAGI-1 Protein 2e-77 41
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-86 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 5e-87 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 5e-87 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 5e-87 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-86 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MSMEG_6297 YP_890515.1 aldehyde dehydrogenase VFG0082 Protein 1e-86 41