Gene Information

Name : lysS (MSMEG_6094)
Accession : YP_890315.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_008596
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 6156246 - 6157769 bp
Length : 1524 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGACCCCAGCCGATCGTGACGACACGTCCCAGCCCCAGGCCGATATCCCCGAGCAGTTCCGAATCCGTCAGGAGAAGCG
GGAGCGGCTGCTGGCGCAGGGGCACGATCCGTACCCGGTGAAGGTCGATCGCACCCACACGCTGGCCGAACTGCGCCGCG
CCCACCCCGACCTGGCCGCCGACACCGCGACCGGCCAGATCGTCGGGGTCTCCGGCCGCGTGGTGTTTGCCCGCAACTCG
GGCAAGTTGTGCTTCGCGACCCTGCAGGAGGGCGACGGCACCCAACTGCAGGTGATGATCAGCCTCGCTCAGGTGGGCCA
GGAGGCACTCGACTCCTGGAAGAGTGACGTGGACCTCGGTGACATCGTGTTCGTCCACGGCGAAGTCATCAGTTCCAAGC
GTGGCGAATTGTCGGTGCTGGCCGACAGATGGCAGATGGCGGCAAAGGCGCTGCGGCCACTTCCGGTTGCTCACAAAGAA
ATGAGCGAAGAAGCGCGCGTGCGTCAGCGCTATGTCGACCTCATCGTCCGGCCCGAGGCCCGCACCATCGCCCGCCAGCG
CGTCGCGGTGGTCCGCGCTGTGCGTTCGGCGCTCGAACGGCGCGGATTCCTCGAGGTCGAGACCCCGATGCTGCAGACGC
TCGCCGGCGGTGCCGCCGCGCGCCCGTTCATCACGCACTCCAATGCGCTCGACATCGATCTGTACCTGAGGATCGCGCCG
GAACTGTTCCTCAAGCGCTGCCTCGTGGGCGGATTTGAGAAGGTTTTCGAGTTGAATCGCAACTTTCGCAATGAGGGTGT
GGATTCCACACACTCGCCGGAATTCGCGATGTTGGAGACATATCAGGCTTACGGTGACTACAACGATTCCGCGACCGTCA
CCCGAGAACTTATTCAAGAGGTCGCCGACGAAGCGATCGGCACGCGTCAGGTGCCATTGCCCGATGGCACGGTCTACGAT
CTCGACGGTGAATGGGACACGGTGGAAATGTACCCATCGCTGTCGGAGGCACTCGGTGACGAGATCACTCCCGAGACCCC
GGTCGAGAAGTTGTGGCAGATTGCGGATCGACTTGAGGTCGAGATTCCGCGTGACCGCGGTTACGGTCACGGGAAATTGA
TCGAAGAACTATGGGAACACACGGTCGGTGACAAGTTGTGGGCCCCGACGTTCGTGCGCGACTTCCCCGTCGAGACGACT
CCACTCACCCGAGCGCATCGCAGCATTCCAGGGGTCACCGAGAAGTGGGACCTGTATGTGAGGAAATTCGAACTCGCCAC
GGGATACTCCGAACTCATCGACCCGGTAATCCAGCGCGAGCGTTTCGAGGCCCAGGCCCGCGCCGCCGCCGCCGGCGACG
ACGAGGCAATGGTTCTCGACGAGGATTTCCTGGCCGCATTGGAGTTCGCGATGCCGCCGACCACGGGAACCGGAATGGGC
ATCGATAGGTTGATGATGGCGTTGACAGGGTTGTCTATTAGGGAGACCGTTTTGTTCCCGATTGTTCGGCGTCACAGCAA
CTGA

Protein sequence :
MTPADRDDTSQPQADIPEQFRIRQEKRERLLAQGHDPYPVKVDRTHTLAELRRAHPDLAADTATGQIVGVSGRVVFARNS
GKLCFATLQEGDGTQLQVMISLAQVGQEALDSWKSDVDLGDIVFVHGEVISSKRGELSVLADRWQMAAKALRPLPVAHKE
MSEEARVRQRYVDLIVRPEARTIARQRVAVVRAVRSALERRGFLEVETPMLQTLAGGAAARPFITHSNALDIDLYLRIAP
ELFLKRCLVGGFEKVFELNRNFRNEGVDSTHSPEFAMLETYQAYGDYNDSATVTRELIQEVADEAIGTRQVPLPDGTVYD
LDGEWDTVEMYPSLSEALGDEITPETPVEKLWQIADRLEVEIPRDRGYGHGKLIEELWEHTVGDKLWAPTFVRDFPVETT
PLTRAHRSIPGVTEKWDLYVRKFELATGYSELIDPVIQRERFEAQARAAAAGDDEAMVLDEDFLAALEFAMPPTTGTGMG
IDRLMMALTGLSIRETVLFPIVRRHSN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 5e-146 65