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Name : MSMEG_5265 (MSMEG_5265) Accession : YP_889511.1 Strain : Mycobacterium smegmatis MC2 155 Genome accession: NC_008596 Putative virulence/resistance : Resistance Product : cystathionine gamma-synthase Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0626 EC number : 2.5.1.48 Position : 5356323 - 5357477 bp Length : 1155 bp Strand : - Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine DNA sequence : ATGAGTGAACACCGCAAGTGGCACGGTCTGGCCACGAAAGCCATCCATGCCGGTTACCAGCCTGACCCGGCGACCGGTGC CGTCAACACGCCGATCTACGCCAGCTCGACGTTCGCCCAGGACGGGGTCGGTGGGCTCCGCGGCGGGTTCGAGTACGCCC GCACCGGCAACCCGACGCGGCAGTCCCTCGAGGCCGCGCTGGCCGCGGTCGAGGAGGCCCGCTTCGGCCGGGCGTTCAGC TCGGGCATGGCCGCCACCGACTGCGCGCTGCGTGCGGTGCTGCGTCCGGGCGATCACGTCGTGATCCCCGACGACGCCTA CGGCGGCACGTTCCGGCTCATCGACAAGGTCTTCACGCACTGGGGCATCAGCCACACCCCGGCCGCGCTGAGCGACCTCG ACTCGGTGCGCTCGGCGATCACGCCCAAGACCCGCCTGATCTGGGTCGAGACCCCGACCAACCCGCTGCTGAACGTCGCC GACATCGCGGGCATAGTGCAGATCGCGTCGTCGACGGGTGTGAAGGTGTTGGTGGACAACACGTTTGCCTCACCGGCTCT GCAGCAGCCGCTGCTGCTGGGCGCCGACATCGTGCTGCACTCGACCACCAAGTACATCGGCGGTCACTCCGACGTCGTCG GCGGTGCGCTGCTGACCAACGACGAGGAACTCGACGCCGCGTTCGCGTTCCTGCAGAACGGCGCGGGCGGTGTGCCCGGA CCGTTCGACGCGTACCTGACCATGCGCGGACTGAAGACCCTGGTGCTGCGGATGCGTCAGCACAGCGAGAACGCCGCGCT GATCGCGGAATTCCTCGACGGGCATCCCGCGGTCCAGACCGTGCTGTACCCCGGTCTGCCCAGCCACCCCAACCACGACG TCGCGGCACGGCAGATGACCGGCTTCGGCGGCATGGTGTCGGTGCGGTTGCGTGGTGGCCCACAGGCCGCGCGTGACTTG TGCTCGCGCACAGAGATCTTCATCCTCGCCGAGTCGCTGGGCGGGGTCGAGTCGCTGATCGAGTACCCGGGCGCGATGAC CCACGCGTCGACCGCGGGCTCGCAGCTCGAGGTGCCCGACGACCTGGTGCGGCTGTCGGTCGGCATCGAGCACTCAGCGG ACCTGCTGGCCGACCTGGAGCAGGCCCTGGGCTGA Protein sequence : MSEHRKWHGLATKAIHAGYQPDPATGAVNTPIYASSTFAQDGVGGLRGGFEYARTGNPTRQSLEAALAAVEEARFGRAFS SGMAATDCALRAVLRPGDHVVIPDDAYGGTFRLIDKVFTHWGISHTPAALSDLDSVRSAITPKTRLIWVETPTNPLLNVA DIAGIVQIASSTGVKVLVDNTFASPALQQPLLLGADIVLHSTTKYIGGHSDVVGGALLTNDEELDAAFAFLQNGAGGVPG PFDAYLTMRGLKTLVLRMRQHSENAALIAEFLDGHPAVQTVLYPGLPSHPNHDVAARQMTGFGGMVSVRLRGGPQAARDL CSRTEIFILAESLGGVESLIEYPGAMTHASTAGSQLEVPDDLVRLSVGIEHSADLLADLEQALG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAS0418 | YP_042545.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 2e-74 | 49 |
| SAR0460 | YP_039909.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 3e-73 | 48 |
| metB | YP_281510.1 | cystathionine beta-lyase | Not tested | Not named | Protein | 5e-55 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| MSMEG_5265 | YP_889511.1 | cystathionine gamma-synthase | BAC0207 | Protein | 8e-62 | 42 |
