Gene Information

Name : rph (MSMEG_4901)
Accession : YP_889156.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_008596
Putative virulence/resistance : Unknown
Product : ribonuclease PH
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0689
EC number : 2.7.7.56
Position : 4994349 - 4995128 bp
Length : 780 bp
Strand : -
Note : RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs

DNA sequence :
GTGTCCAGACGAGAAGACGGGCGGCTTGACGACGAGCTGCGTCCAGTGGTGATCACCCGCGGCTTCACCTCGCATCCGGC
GGGTTCGGTGCTCGTGGAGTTCGGCCAGACCCGGGTCATGTGTACGGCATCGGTGACCGAGGGGGTGCCGCGCTGGCGCA
AGGGCTCCGGGCAGGGCTGGCTCACCGCGGAGTACGCGATGCTGCCCGCCGCCACGCACGACCGCTCGGACCGTGAGTCG
GTCAAGGGCCGCATCGGCGGCCGCACGCAGGAGATCAGCCGGCTGATCGGCCGGTCGCTGCGCGCGTGCATCGACCTCGC
GGCGCTGGGCGAGAACACCATCGCGATCGACTGCGATGTGCTGCAGGCCGACGGCGGCACGCGCACCGCGGCCATCACGG
GCGCCTACGTGGCGCTGTCCGACGCGGTGACGTGGCTCGCCGCGGCGGGCCGGCTGTCGGATCCGCGGCCGCTTTCGTGC
GCGATCGCCGCCGTGTCGGTCGGCGTGGTCGACGGACGCGTGCGGGTCGACCTGCCCTACTCCGAGGATTCGCGTGCCGA
GGTCGACATGAACGTCGTCGCCACCGACACGGGAACGCTCGTCGAGATCCAGGGCACCGGCGAAGGGGCCACGTTCCCGC
GCTCGACGCTCGACAAGATGCTCGACGCCGCGCTCGGGGCCACCGAGCAGTTGTTCGTGCTGCAGCGTGAGGCGCTCGAC
GCGCCGTACCCGGGTGTGCTTCCCGAGGGGCCGGCCCCGAAAAAGGCGTTCGGAAGCTGA

Protein sequence :
MSRREDGRLDDELRPVVITRGFTSHPAGSVLVEFGQTRVMCTASVTEGVPRWRKGSGQGWLTAEYAMLPAATHDRSDRES
VKGRIGGRTQEISRLIGRSLRACIDLAALGENTIAIDCDVLQADGGTRTAAITGAYVALSDAVTWLAAAGRLSDPRPLSC
AIAAVSVGVVDGRVRVDLPYSEDSRAEVDMNVVATDTGTLVEIQGTGEGATFPRSTLDKMLDAALGATEQLFVLQREALD
APYPGVLPEGPAPKKAFGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
rph YP_001800860.1 ribonuclease PH Not tested Not named Protein 9e-64 67