Gene Information

Name : trpE (MSMEG_3217)
Accession : YP_887531.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_008596
Putative virulence/resistance : Unknown
Product : anthranilate synthase component I
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0147
EC number : 4.1.3.27
Position : 3294784 - 3296358 bp
Length : 1575 bp
Strand : +
Note : with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine

DNA sequence :
GTGCAGACCACCGCCAACCATTCCTCACGCTCCACGCAGACCGGCACGCGCGCCCACGGCGCCGCACTCGCCGAGACCAC
GTCGCGCGAGGACTTCCGGGCGCTGGCGACCGAGCACCGTGTGGTCCCCGTCATCCGCAAGGTGCTCGCCGACAGCGAGA
CACCCCTGTCGGCCTACCGCAAGCTCGCCGCCAACCGGCCAGGGACGTTCTTGCTGGAATCCGCGGAGAACGGTCGGTCG
TGGTCGCGATGGTCGTTCATCGGCGCGGGAGCGCCGTCGGCGCTGACCGTGCGCGACAACGCGGCGGCATGGCTGGGCAC
CGCGCCCGAGGGGGCGCCGAGCGGCGGTGATCCGCTCGATGCGCTGCGCGCAACCCTCGATCTGCTCAAGACCGAGGCCA
TGGCGGGTCTGCCGCCCCTGTCGTCGGGTCTGGTCGGCTTCTTCGCCTATGACATGGTGCGCCGGCTCGAACGGCTGCCG
GAACTCGCGGTCGACGATCTCGGGCTGCCGGACATGCTGCTGCTGCTCGCGACCGACATCGCCGCGGTCGACCACCACGA
GGGCACCATCACGCTCATCGCCAACGCGGTGAACTGGAACGGCACCGACGAGCGGGTCGACTGGGCCTACGACGACGCGG
TCGCGCGTCTGGACGTGATGACCAAGGCGCTGGGGCAGCCGTTGACCTCGGCGGTGGCGACGTTCAGCAGGCCCGCGCCC
GATCACCGGGCGCAGCGCACGATGGAGGAGTACACCGAGATCGTCGACAAGCTGGTCGGCGACATCGAGGCCGGCGAGGC
ATTTCAGGTGGTGCCCTCGCAACGGTTCGAGATGGACACCGCGGCCGATCCGTTGGACGTCTACCGCATCCTGCGGGTGA
CCAACCCCAGCCCGTACATGTACCTGCTCAACATCCCCGACGCCGACGGAGGACTGGACTTCTCGATCGTCGGGTCGAGC
CCAGAGGCGCTGGTGACGGTCAAGGACGGACGCGCCACCACGCATCCCATCGCGGGCACGCGGTGGCGCGGCGCCACCGA
GGAAGAGGACGTGCTGCTCGAAAAGGAGCTGCTCGCCGACGAGAAGGAACGCGCCGAGCACCTCATGCTCGTCGACCTGG
GCCGCAACGACCTGGGCCGGGTGTGCCGGCCCGGCACCGTGCGTGTCGACGACTACAGCCACATCGAGCGCTACAGCCAC
GTCATGCATCTGGTGTCGACGGTCACCGGTGAGCTCGCCGAGGACAAGACCGCCCTTGACGCGGTGACGGCGTGCTTCCC
GGCGGGCACGTTGTCGGGTGCGCCGAAGGTGCGTGCCATGGAGCTCATCGAGGAGGTCGAGAAGACACGCCGCGGCCTCT
ACGGCGGTGTCGTCGGGTACCTCGACTTCGCGGGCAACGCCGACTTCGCCATCGCCATCCGCACCGCACTGATGCGCAAC
GGAACCGCCTACGTGCAGGCCGGCGGGGGAGTCGTGGCCGACTCCAACGGCCCGTACGAGTACACCGAGGCCGCCAACAA
GGCCCGTGCGGTGCTCAACGCGATCGCCGCGGCAGCGACCCTGGCGGAACCATGA

Protein sequence :
MQTTANHSSRSTQTGTRAHGAALAETTSREDFRALATEHRVVPVIRKVLADSETPLSAYRKLAANRPGTFLLESAENGRS
WSRWSFIGAGAPSALTVRDNAAAWLGTAPEGAPSGGDPLDALRATLDLLKTEAMAGLPPLSSGLVGFFAYDMVRRLERLP
ELAVDDLGLPDMLLLLATDIAAVDHHEGTITLIANAVNWNGTDERVDWAYDDAVARLDVMTKALGQPLTSAVATFSRPAP
DHRAQRTMEEYTEIVDKLVGDIEAGEAFQVVPSQRFEMDTAADPLDVYRILRVTNPSPYMYLLNIPDADGGLDFSIVGSS
PEALVTVKDGRATTHPIAGTRWRGATEEEDVLLEKELLADEKERAEHLMLVDLGRNDLGRVCRPGTVRVDDYSHIERYSH
VMHLVSTVTGELAEDKTALDAVTACFPAGTLSGAPKVRAMELIEEVEKTRRGLYGGVVGYLDFAGNADFAIAIRTALMRN
GTAYVQAGGGVVADSNGPYEYTEAANKARAVLNAIAAAATLAEP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00338 YP_008207803.1 Anthranilate/para-aminobenzoate synthases component I Not tested AbaR25 Protein 7e-68 43
BJAB0868_00342 YP_008211668.1 Anthranilate/para-aminobenzoate synthases component I Not tested AbaR26 Protein 7e-68 43