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Name : tkt (MSMEG_3103) Accession : YP_887418.1 Strain : Mycobacterium smegmatis MC2 155 Genome accession: NC_008596 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : 2.2.1.1 Position : 3177527 - 3179617 bp Length : 2091 bp Strand : - Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo DNA sequence : GTGACCACGGCCGAAGAGATCACCGCTCTCACCCAGCCCAACCACCCCGACGATTGGACCGATCTCGACACGCTCAGCGT CGACACGGCACGGGTGCTCGCGGCTGACGCGGTACAGAAGGTCGGCAACGGCCACCCGGGTACGGCGATGAGCCTCGCGC CGCTCGCGTACACGCTGTTCCAGCGGCAGATGCGCCATGACCCCAGCGACACGCACTGGCTGGGTCGCGACCGCTTCATC CTGTCCTGCGGGCATTCGAGCCTGACGCTGTACATCCAGCTCTACCTCGGTGGCTTCGGTCTGGAGCTCTCCGACATCGA ATCGCTGCGCACGTGGGGTTCCAAGACCCCGGGCCACCCCGAGTTCCGCCACACCAAGGGCGTCGAGATCACCACCGGGC CGCTCGGCCAGGGTCTGGCCTCGGCCGTCGGCATGGCGATGGCCGCTCGCTACGAGCGCGGCCTGTTCGATCCCGACGCC GCACCCGGCACCAGCCCGTTCGACCACTACATCTACGTCGTGGCATCCGACGGCGACATGGAGGAGGGCGTCACCAGCGA GGCGTCGTCGCTGGCGGGAACGCAGCAGCTGGGCAACCTGATCGTCATCTGGGACGACAACAAGATCTCCATCGAGCACA ACACCGACATCGCCTTCAGCGAGGACGTGGTCGCGCGCTACCGCGCCTACGGGTGGCACGTGCAGGAAGTGCAGGGCGGC GAGAACGTCGTCGGCATCGAGCAGGCGCTCGAAGAGGCCCGCAAGGTCACCGACAAGCCGTCGTTCATCGCGCTGCGGAC CATCATCGGCTACCCCGCGCCCAACAAGATGAACACCGGCGGCGTGCACGGGTCGGCGCTCGGCGCCGACGAGGTCGCCG CCACCAAGAAGATCCTCGGCTTCGACCCCGAGAAGAACTTCGAGGTGCGCGACGAGGTGATCGCGCACACCCGCGAGCTC GTCGCCCGCGGCAAGAAGGCCCACGACGAGTGGCAGGTGTCCTTCGACGAGTGGGCCGAGCGTGAGCCCGAGCGCAAGGA GCTGCTCGACCGTCTGCTGGCCGGCAAGTTGCCCGAGGGCTGGGACGCCGACCTGCCGCACTGGGACCTCGACGCCAAGC CCGTCGCGACGCGCGCGGCCTCGGGTGCGGTGCTCTCGGCGGTCGGGCCGAAACTGCCCGAGCTGTGGGGCGGTTCGGCC GACCTCGCGGGCAGCAACAACACCACGATCAAGGGCGCCAACTCGTTCGGTCCCCCGTCGATTTCCACCGAGGACTGGAA CGCCACCTGGTACGGCCGCACGCTGCACTTCGGTGTGCGCGAGCACGCGATGGGCGCGATCCTGTCCGGCATCGTGCTGC ACGGCCCGACACGCGCTTACGGCGGAACCTTCCTGCAGTTCTCGGATTACATGCGGCCCGCGGTGCGTTTGGCCTCATTG ATGGACATCGACCCGATCTACGTGTGGACGCACGATTCGATCGGTCTCGGTGAGGACGGCCCGACCCACCAGCCGATCGA GCATCTCGCGGCACTGCGCGCGATCCCGAACCTGTCGGTGGTGCGCCCGGGTGACCCCAACGAGACCGCCTACGCGTGGA AGAGCGTGCTGGAGCGCGGCTCCAGCAGCGGCCCGGTCGGCATGATCCTGACGCGCCAGCCGATCCCGGTGCTCGAAGGC ACCGACCCCGAGGGTGTGGCTCGCGGCGGATACGTGCTGGGCGGCACGCCCGAGAAGAACCCGGATGTCGTGATCATCGG CACCGGTTCGGAGCTGCAGCTCGCGGTGGGAGCGCAGAAGATCCTGGCGGACAAGGGAATCACCGCCAGCGTGGTGTCGA TGCCGTGCGTCGAGTGGTTCGAGTCGCAGCCCGAGGAATACCGCGACTCGGTGCTCCCGCCCGCGGTGTCGGCGCGTGTG GCGGTCGAGGCCGCCGTGGCGCAGAGTTGGTACAAGCTGGTCGGCGACACCGGCGAGATCGTCTCGATCGAGCACTACGG CGAGTCGGCCGACGACAAGACGTTGTTCCGCGAGTTCGGTTTCACCCCGGAAGCGGTGGCCGCTGCGGCGGAGCGATCGC TCGAGAACTGA Protein sequence : MTTAEEITALTQPNHPDDWTDLDTLSVDTARVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRQMRHDPSDTHWLGRDRFI LSCGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTKGVEITTGPLGQGLASAVGMAMAARYERGLFDPDA APGTSPFDHYIYVVASDGDMEEGVTSEASSLAGTQQLGNLIVIWDDNKISIEHNTDIAFSEDVVARYRAYGWHVQEVQGG ENVVGIEQALEEARKVTDKPSFIALRTIIGYPAPNKMNTGGVHGSALGADEVAATKKILGFDPEKNFEVRDEVIAHTREL VARGKKAHDEWQVSFDEWAEREPERKELLDRLLAGKLPEGWDADLPHWDLDAKPVATRAASGAVLSAVGPKLPELWGGSA DLAGSNNTTIKGANSFGPPSISTEDWNATWYGRTLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLASL MDIDPIYVWTHDSIGLGEDGPTHQPIEHLAALRAIPNLSVVRPGDPNETAYAWKSVLERGSSSGPVGMILTRQPIPVLEG TDPEGVARGGYVLGGTPEKNPDVVIIGTGSELQLAVGAQKILADKGITASVVSMPCVEWFESQPEEYRDSVLPPAVSARV AVEAAVAQSWYKLVGDTGEIVSIEHYGESADDKTLFREFGFTPEAVAAAAERSLEN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 9e-121 | 44 |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 7e-115 | 44 |
