Gene Information

Name : MSMEG_2488 (MSMEG_2488)
Accession : YP_886827.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_008596
Putative virulence/resistance : Unknown
Product : [NADP+] succinate-semialdehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.16
Position : 2571561 - 2573021 bp
Length : 1461 bp
Strand : +
Note : identified by match to protein family HMM PF00171

DNA sequence :
ATGACGGAGCACGAGAACCGCGTGGTGAGCGGCGTTCAGAAGCGGCTCTTCATCGACGGCAAGTGGGTGGACGCGACAGA
TGGCGCCACATTCGACGTCCTCGATCCGGCGACCGGCGAGGTGTTGTGCGCGGTCGCCGACGCCTCGCCGCAGGACGGCC
GTGCGGCACTCGACGCCGCCGTCGCCGCGCAACCGGAGTTCGCCGCTCTTCCGCCGCGTGAACGCGCCGACATGCTCACC
GGGGCGTTCGAACTGCTGCACGAGCGCATCGACGACCTGGCGCTGCTGATGACGCTCGAGATGGGCAAGCCCCTCGCCGA
GGCGCGCGGTGAGATCACCTACGCCGCAGAGTTCTTCCGGCACTTCGCCGCCGAGGCGGTCCGTATCGACGGCGGCTACC
AGACCGCGCCCGCGGGCGGGTCGCGCTTCTTGATCGCGCGGCAGCCGGTGGGGCCGTGCCTGCTCATCACGCCGTGGAAC
TTCCCCATGGCGATGGGCACCCGCAAGCTGGGGCCCGCCATCGCGGCCGGGTGCACGAGCGTCATCAAACCTGCCCACCA
GACCCCGTTGTCGATGCTGGCGCTCATGGACATCCTCTCGGAGGTCGGCGTGCCCGCCGGCGCCGTCAACTGCGTCACCG
CCATGGACGCCGGCGGCGTGATGGAACCTCTCATAAGGTCCGGTCTGGCACGCAAGCTCTCGTTCACCGGGTCCACCAAG
GTGGGGCGCATGCTGCTGGAGCAGTGCGCCGAGAAGATTCTGCGCACCTCACTCGAACTCGGCGGCAACGCACCGTTGAT
CGTGTTCGAGGACGCCGATCTCGACGAGGCCGTCGAGGGCGCGATCCTCGCCAAGATGCGCAACATGGGGGAGGCCTGCA
CGGCCGCCAACCGGCTGTTCGTGCACTCGTCGGTGATCGACGAATTCGGCAGGCGCCTTGCCGAGCGCATGGCGGAGATG
CCCGTCGGGCGCGGTACCGAGGACGGTGTGCGGGTGGGGCCGCTGATCGACGAGGCCGCACTGCAGAAGGTCACGTCGCT
GGTCGACGACGCGGTCAAGCGCGGCGCCACCGTGCTGACCGGTGGCTCGGCGCCGTCGGGTCCCGGGTTCTTCTATCCGC
CGACGGTGCTCAGCGGTGTGCCGCGCGACGCGGAGATGGTGGGCCAGGAGATCTTCGGGCCGGTCGCGCCGCTGACGCCG
TTCGATACCGAGGAAGAGGCCGTGGCCGCCGCCAACGACACCGAATACGGGCTCGTCTCTTACGTTTTCACCAATGACCT
GCGTCGCGCGCTGCGCGTCGCGGAGGCACTCGAAACCGGCATGGTCGGGCTCAACCAGGGCATCGTCTCCAACCCCGCGG
CGCCGTTCGGCGGCATCAAGGAATCCGGCCTCGGACGGGAAGGCGGCGCGGTCGGTATCGACGAGTTCCTGGAGACCAAG
TACGTCGGTATCAAGATGTGA

Protein sequence :
MTEHENRVVSGVQKRLFIDGKWVDATDGATFDVLDPATGEVLCAVADASPQDGRAALDAAVAAQPEFAALPPRERADMLT
GAFELLHERIDDLALLMTLEMGKPLAEARGEITYAAEFFRHFAAEAVRIDGGYQTAPAGGSRFLIARQPVGPCLLITPWN
FPMAMGTRKLGPAIAAGCTSVIKPAHQTPLSMLALMDILSEVGVPAGAVNCVTAMDAGGVMEPLIRSGLARKLSFTGSTK
VGRMLLEQCAEKILRTSLELGGNAPLIVFEDADLDEAVEGAILAKMRNMGEACTAANRLFVHSSVIDEFGRRLAERMAEM
PVGRGTEDGVRVGPLIDEAALQKVTSLVDDAVKRGATVLTGGSAPSGPGFFYPPTVLSGVPRDAEMVGQEIFGPVAPLTP
FDTEEEAVAAANDTEYGLVSYVFTNDLRRALRVAEALETGMVGLNQGIVSNPAAPFGGIKESGLGREGGAVGIDEFLETK
YVGIKM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
orf17 AAO17183.1 Orf17 Not tested tcd island Protein 7e-100 48
cur_1509 YP_001800903.1 NAD-dependent aldehyde dehydrogenase Not tested Not named Protein 5e-99 46