Gene Information

Name : nrdF2 (MSMEG_2313)
Accession : YP_886661.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_008596
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 2393815 - 2394789 bp
Length : 975 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
GTGTCCGACGGAATCAAGCTGATCGACCGTGTCTCAGCCATCAACTGGAACCGGCTCCAGGATGAGAAGGACGCCGAGGT
GTGGCACCGGCTCACCGGCAATTTCTGGTTGCCGGAGAAGGTGCCGGTGTCCAACGACATCCAGTCCTGGCACACCCTCA
CCGACAACGAGAAGCAGCTGACAATGCGGGTGTTCACCGGCCTGACGCTGCTCGACACCATCCAGGGCACCGTCGGCGCG
GTCAGCCTGATCCCTGACGCGGTCACCCCGCACGAGGAGGCCGTGCTCACCAACATCGCGTTCATGGAGTCGGTGCACGC
CAAGAGCTACAGCAACATCTTCTCGACGCTGTGCTCGACCGCCGAGATCGACGACGCGTTCCGCTGGTCCGAGGAGAACC
CGAACCTGCAGCGCAAGGCCGCGATCGTGATGCAGTACTACCGCGGCGACGAGCCGCTCAAGCGCAAGGTGGCCTCGACG
CTGCTGGAGAGCTTCCTGTTCTACTCGGGCTTCTACCTGCCGATGTACTGGTCCAGCCGCGCCAAGCTGACCAACACCGC
CGACATGATCCGCCTGATCATCCGCGACGAGGCCGTGCACGGCTACTACATCGGCTACAAGTACCAGCGCGGGCTCGCCC
TCGTCGACGAGGAAAAGAAGCAGGAGCTCAAGGACTACACCTACGAACTGCTCTTCGAGCTCTACGACAACGAGGTCGAG
TACACCCAGGACCTCTACGACAGCGTCGGCCTGACCGAGGACGTCAAGAAGTTCCTGCGCTACAACGCCAACAAGGCCCT
GATGAACCTCGGCTACGAGGCGCTGTTCCCGCGCGACGAGACCGACGTCAACCCGGCGATCCTCTCGGCGCTGGCGCCCA
ACGCCGACGAGAACCACGACTTCTTCTCCGGCTCGGGGTCGAGCTACGTGATCGGCAAGGCCGTCAACACCGAAGACGAG
GACTGGGACTTCTAG

Protein sequence :
MSDGIKLIDRVSAINWNRLQDEKDAEVWHRLTGNFWLPEKVPVSNDIQSWHTLTDNEKQLTMRVFTGLTLLDTIQGTVGA
VSLIPDAVTPHEEAVLTNIAFMESVHAKSYSNIFSTLCSTAEIDDAFRWSEENPNLQRKAAIVMQYYRGDEPLKRKVAST
LLESFLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKYQRGLALVDEEKKQELKDYTYELLFELYDNEVE
YTQDLYDSVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAILSALAPNADENHDFFSGSGSSYVIGKAVNTEDE
DWDF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 3e-114 75