Gene Information

Name : MSMEG_2299 (MSMEG_2299)
Accession : YP_886648.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_008596
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 2381113 - 2383233 bp
Length : 2121 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
GTGTTGCCGGGGGAGGCGGATTACCACGCGCTCAACGCGATGCTGAATCTGTACGACGCCGACGGCAAGATTCAGTTCGA
AAAGGACAGGGAAGCCGCCAAGCAGTACTTCCTGCAGCACGTCAACCAGAACACGGTCTTCTTCCACAGCCAGGACGAGA
AGCTCGACTACCTGATCGAGAACGAGTACTACGAGCGCGAGGTGCTCGACCAGTACTCCCGCGACTTCATCAAGAGCCTG
CTGGACCGCGCGTACGCCAAGAAGTTTCGGTTCCCCACGTTCCTCGGTGCGTTCAAGTACTACACGTCCTACACGCTGAA
GACCTTCGACGGTAAGCGCTACCTGGAGCGTTTCGAGGACCGCGTCGTCATGGTCGCGTTGACCCTGGCCGCAGGCGACA
CCGAACTCGCCGAGAAACTCGTCGACGAGATCATCGACGGCCGGTTCCAGCCGGCCACCCCCACGTTCCTCAACTCGGGC
AAGAAGCAGCGCGGCGAGCCGGTGTCCTGCTTCCTGTTGCGCATCGAGGACAACATGGAGTCCATCGGGCGTTCCATCAA
CTCGGCGCTGCAGCTGTCCAAGCGCGGCGGCGGAGTCGCGCTGCTGCTGAGCAACATCCGCGAGCACGGCGCGCCCATCA
AGAACATCGAGAACCAGAGCTCGGGCGTCATCCCCATCATGAAGCTGCTGGAGGACTCGTTCTCCTACGCCAATCAGCTG
GGTGCCCGTCAGGGCGCGGGCGCGGTGTACCTGCACGCCCACCACCCCGACATCTACCGGTTCCTGGACACCAAGCGCGA
GAACGCCGACGAGAAGATCCGGATCAAGACGCTCTCGCTGGGTGTCGTGATCCCCGACATCACCTTCGAGCTGGCCAAGA
AGAACGAGGACATGTACCTGTTCTCGCCGTACGACGTCGAGCGCGTCTACGGGGTGCCGTTCGCCGACGTCTCGGTCACC
GAGAAGTACTACGAGATGGTCGACGACGCGCGGATCCGCAAGACCAAGATCAACGCGCGCGAGTTCTTCCAGACGCTGGC
CGAGCTGCAGTTCGAATCGGGCTACCCGTACATCATGTTCGAGGACACCGTGAACCGGTCCAACCCGATCGCGGGCAAGA
TCACGCACTCGAACCTGTGCTCGGAGATCCTGCAGGTCTCCACGCCGTCGGAGTTCAACGACGACCTGTCCTACGCCAAG
GTGGGCAAGGACATCTCCTGCAACCTCGGCTCGCTCAACATCGCCAAGGCCATGGACTCGCCGGACTTCGCGCAGACCAT
CGAGGTGGCGATCCGTGCGCTCACCGCGGTGAGCGATCAGACCCACATCACGTCCGTGCCGTCGATCGAGCAGGGCAACA
ACGATTCCCACGCCATCGGCCTGGGGCAGATGAACCTGCACGGATACCTTGCGCGGGAACGCATCTACTACGGTTCCGAA
GAGGGCATCGACTTCACGAACATCTACTTCTACACGGTGCTGTTCCACGCGCTGCGCGCGTCGAACAAGATCGCGATCGA
GCGCGGGACGCACTTCAAGGGATTCGAGAAGTCCAAGTACGCCTCGGGCGAGTTCTTCGACAAGTACACCGATCAGGTGT
GGGAGCCCAAGACCGACAAGGTGCGCCGGCTGTTCGCCGACGCCGATATCCACATCCCCACGCAGGACGACTGGAAGCAG
TTGAAGGAGTCGGTGCAGAAGCACGGCATCTACAACCAGAACCTGCAGGCCGTCCCGCCGACGGGGTCGATCTCCTACAT
CAACCACTCGACGTCGTCGATCCACCCGGTCGCGTCGAAGATCGAGATCCGCAAGGAAGGCAAGATCGGTCGCGTCTACT
ACCCGGCGCCGTACATGACCAACGACAACCTGGACTACTACCAGGACGCGTATGAGATCGGGTACGAGAAGATCATCGAC
ACCTACGCCGCGGCCACCCAGCACGTGGACCAGGGTCTGAGCCTGACGTTGTTCTTCAAGGACACCGCCACCACGCGTGA
CGTGAACAAGGCCCAGATCTACGCATGGCGCAAGGGCATCAAGACGCTCTACTACATCCGCCTGCGCCAGATGGCCTTGG
AGGGAACCGAAGTCGAGGGTTGCGTCAGCTGCATGCTGTGA

Protein sequence :
MLPGEADYHALNAMLNLYDADGKIQFEKDREAAKQYFLQHVNQNTVFFHSQDEKLDYLIENEYYEREVLDQYSRDFIKSL
LDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLERFEDRVVMVALTLAAGDTELAEKLVDEIIDGRFQPATPTFLNSG
KKQRGEPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLSNIREHGAPIKNIENQSSGVIPIMKLLEDSFSYANQL
GARQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKKNEDMYLFSPYDVERVYGVPFADVSVT
EKYYEMVDDARIRKTKINAREFFQTLAELQFESGYPYIMFEDTVNRSNPIAGKITHSNLCSEILQVSTPSEFNDDLSYAK
VGKDISCNLGSLNIAKAMDSPDFAQTIEVAIRALTAVSDQTHITSVPSIEQGNNDSHAIGLGQMNLHGYLARERIYYGSE
EGIDFTNIYFYTVLFHALRASNKIAIERGTHFKGFEKSKYASGEFFDKYTDQVWEPKTDKVRRLFADADIHIPTQDDWKQ
LKESVQKHGIYNQNLQAVPPTGSISYINHSTSSIHPVASKIEIRKEGKIGRVYYPAPYMTNDNLDYYQDAYEIGYEKIID
TYAAATQHVDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKTLYYIRLRQMALEGTEVEGCVSCML

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 80