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Name : smpB (MSMEG_2091) Accession : YP_886451.1 Strain : Mycobacterium smegmatis MC2 155 Genome accession: NC_008596 Putative virulence/resistance : Unknown Product : SsrA-binding protein Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0691 EC number : - Position : 2167390 - 2167875 bp Length : 486 bp Strand : + Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca DNA sequence : GTGACCAAGAAGAGCGCCTCCAGCAACAACAAGGTGGTCGCCACCAACCGCAAGGCGCGACACAACTACACGATCCTCGA CACCTACGAGGCCGGGATCGTGTTGATGGGCACGGAGGTCAAGAGCCTGCGCGAAGGTCAGGCCTCGCTGGCCGACGCGT TCGCCACGGTCGACGACGGCGAGATCTGGCTGCGCAACGTCCACATCGCCGAATATCACCACGGCACCTGGACCAACCAC GCGCCGCGGCGCAACCGCAAACTGCTGCTGCACCGCAAGCAGATCGACAACCTCATCGGCAAGATCCGCGACGGCAACCT CACGCTGGTGCCGCTGTCGATCTACTTCACCGACGGCAAGGTCAAGGTCGAGTTGGCGCTCGCCCGCGGCAAGCAGGCCC ACGACAAGCGCCAGGACCTCGCCCGTCGAGACGCTCAACGCGAGGTGATCCGCGAGCTGGGCCGCCGGGCCAAGGGCAAG ATCTGA Protein sequence : MTKKSASSNNKVVATNRKARHNYTILDTYEAGIVLMGTEVKSLREGQASLADAFATVDDGEIWLRNVHIAEYHHGTWTNH APRRNRKLLLHRKQIDNLIGKIRDGNLTLVPLSIYFTDGKVKVELALARGKQAHDKRQDLARRDAQREVIRELGRRAKGK I |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| smpB | YP_001800894.1 | SsrA-binding protein | Not tested | Not named | Protein | 5e-50 | 68 |
| unnamed | AET14351.1 | SsrA-binding protein | Not tested | SaPI68111 | Protein | 2e-31 | 51 |
| smpB | NP_230495.1 | SsrA-binding protein | Not tested | VPI-1 | Protein | 8e-24 | 42 |
