Gene Information

Name : mtrA (MSMEG_1874)
Accession : YP_886240.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_008596
Putative virulence/resistance : Virulence
Product : DNA-binding response regulator MtrA
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 1950437 - 1951123 bp
Length : 687 bp
Strand : +
Note : identified by similarity to SP:Q50447; match to protein family HMM PF00072; match to protein family HMM PF00486

DNA sequence : 
ATGGACACCATGAGGCAAAGGATCCTTGTCGTCGATGACGACCCGTCACTGGCCGAGATGCTCACCATCGTTCTGCGTGG
TGAGGGTTTCGACACCGCGGTCATCGGCGACGGCAGCCAGGCACTCACCGCTGTCCGGGAGCTCAGGCCGGACCTGGTCC
TGCTCGATTTGATGCTGCCTGGGATGAACGGCATCGATGTGTGCCGTGTGCTGCGCGCCGACTCCGGCGTGCCGATCGTC
ATGCTGACCGCCAAGACCGACACCGTCGACGTGGTGCTGGGCCTGGAATCCGGAGCCGACGACTATGTGATGAAGCCGTT
CAAGCCGAAGGAGCTCGTCGCGCGCGTGCGGGCCCGGCTGCGGCGCAACGAGGACGAGCCCGCCGAGATGCTGTCGATCG
GTGACGTCGAGATCGACGTGCCCGCGCACAAGGTGACCCGGCAAGGCGAGCAGATTTCGCTGACACCGCTGGAGTTCGAC
CTGCTGGTGGCCCTGGCACGCAAACCACGGCAGGTGTTTACTCGGGATGTGCTGCTCGAACAGGTGTGGGGATACCGTCA
CCCCGCTGACACCCGTTTGGTGAACGTGCATGTCCAGCGGTTGCGGGCAAAGGTGGAGAAAGACCCGGAGAACCCGCAGG
TGGTCCTGACCGTTCGAGGAGTGGGATACAAGGCCGGACCCCCGTGA

Protein sequence : 
MDTMRQRILVVDDDPSLAEMLTIVLRGEGFDTAVIGDGSQALTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIV
MLTAKTDTVDVVLGLESGADDYVMKPFKPKELVARVRARLRRNEDEPAEMLSIGDVEIDVPAHKVTRQGEQISLTPLEFD
LLVALARKPRQVFTRDVLLEQVWGYRHPADTRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 8e-29 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mtrA YP_886240.1 DNA-binding response regulator MtrA AE000516.2.gene3505. Protein 2e-85 97
mtrA YP_886240.1 DNA-binding response regulator MtrA NC_002952.2859905.p0 Protein 3e-37 46
mtrA YP_886240.1 DNA-binding response regulator MtrA NC_002951.3237708.p0 Protein 3e-37 46
mtrA YP_886240.1 DNA-binding response regulator MtrA NC_003923.1003749.p0 Protein 2e-37 46
mtrA YP_886240.1 DNA-binding response regulator MtrA NC_002758.1121668.p0 Protein 3e-37 46
mtrA YP_886240.1 DNA-binding response regulator MtrA NC_009641.5332272.p0 Protein 3e-37 46
mtrA YP_886240.1 DNA-binding response regulator MtrA NC_013450.8614421.p0 Protein 3e-37 46
mtrA YP_886240.1 DNA-binding response regulator MtrA NC_007793.3914279.p0 Protein 3e-37 46
mtrA YP_886240.1 DNA-binding response regulator MtrA NC_007622.3794472.p0 Protein 3e-37 46
mtrA YP_886240.1 DNA-binding response regulator MtrA NC_002745.1124361.p0 Protein 3e-37 46
mtrA YP_886240.1 DNA-binding response regulator MtrA NC_009782.5559369.p0 Protein 3e-37 46
mtrA YP_886240.1 DNA-binding response regulator MtrA HE999704.1.gene2815. Protein 3e-31 44
mtrA YP_886240.1 DNA-binding response regulator MtrA AE015929.1.gene1106. Protein 3e-25 43
mtrA YP_886240.1 DNA-binding response regulator MtrA BAC0125 Protein 6e-26 43
mtrA YP_886240.1 DNA-binding response regulator MtrA NC_012469.1.7685629. Protein 7e-32 43
mtrA YP_886240.1 DNA-binding response regulator MtrA BAC0197 Protein 4e-24 42
mtrA YP_886240.1 DNA-binding response regulator MtrA CP001918.1.gene3444. Protein 2e-26 42
mtrA YP_886240.1 DNA-binding response regulator MtrA BAC0039 Protein 1e-26 42
mtrA YP_886240.1 DNA-binding response regulator MtrA CP000034.1.gene2186. Protein 1e-26 42
mtrA YP_886240.1 DNA-binding response regulator MtrA NC_002695.1.916589.p Protein 9e-27 42
mtrA YP_886240.1 DNA-binding response regulator MtrA BAC0111 Protein 6e-22 41
mtrA YP_886240.1 DNA-binding response regulator MtrA NC_012469.1.7686381. Protein 2e-33 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mtrA YP_886240.1 DNA-binding response regulator MtrA VFG1390 Protein 6e-27 43
mtrA YP_886240.1 DNA-binding response regulator MtrA VFG1389 Protein 5e-24 43
mtrA YP_886240.1 DNA-binding response regulator MtrA VFG1702 Protein 3e-29 41