Gene Information

Name : MSMEG_1543 (MSMEG_1543)
Accession : YP_885925.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_008596
Putative virulence/resistance : Virulence
Product : eptc-inducible aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 1633314 - 1634858 bp
Length : 1545 bp
Strand : +
Note : identified by match to protein family HMM PF00171

DNA sequence :
GTGTCCGAACAGGAGAAAGCCATGACTGTTTACGCACGTCCGGGCGCAGACGGCGCCAAGATGTCGTTCCAGGCCCGCTA
CGACAACTACATCGGCGGCGAGTGGGTCGCCCCGGTCGAGGGCCGCTACTTCGAGAATCCGACGCCGGTGACCGGTCAGG
TGTTCTGCGAGGTGGCCCGCTCCAGCGAGGCCGACATCGACAAGGCTCTCGACGCCGCACACGCCGCGGCGCCCGCGTGG
GGCAAGACCGCCCCGGCCGAGCGCGCGCTGATCCTCAACCGCATCGCCGATCGCATGGAGGAGAACCTCGAATCCATCGC
GCTGGCCGAGTCGTGGGACAACGGCAAGCCGATCCGCGAGACGCTCAACGCCGACATCCCGCTGGCCATCGACCACTTCC
GCTACTTCGCGGGCGTGCTGCGTGCCCAGGAAGGCTCGCTGAGCCAGATCGACGAGGACACCGTCGCCTACCACTTCCAC
GAGCCGCTGGGCGTGGTCGGGCAGATCATCCCGTGGAACTTCCCGATCCTGATGGCGGTGTGGAAGCTGGCCCCGGCCCT
GGCTGCGGGCAACGCCGTCGTCCTCAAGCCCGCCGAGCAGACCCCTGTCTCGGTGCTCTACCTGTTCTCACTCATCGGCG
ACCTGCTGCCCGCCGGTGTGGTCAACATCGTCAACGGGTTCGGTGTGGAGGCCGGCAAGCCGCTGGCGTCGAGCAACCGC
ATCGCCAAGATCGCGTTCACCGGTGAGACCACCACGGGCCGGCTGATCATGCAGTACGCGTCGCAGAACCTGATCCCGGT
GACCCTGGAACTCGGCGGCAAGAGCCCCAACATCTTCTTCAACAACGTGCTCGCGCAGGCCGACGACTACCAGGACAAGG
CGCTGGAGGGCTTCACGATGTTCGCCCTCAACCAGGGTGAGGTGTGCACGTGCCCGTCGCGGTCGCTGATCCAGTCCGAC
ATCTTCGACGAGTTCCTCGAGCTCGCCGCGATCCGCACCAAGGCCGTGCGCCAGGGCGATCCGCTGGACACCGAGACCAT
GATCGGTGCGCAGGCGTCCAACGATCAGCTGGAGAAGATCCTGTCCTACATCGAGATCGGCAAATCCGAAGGGGCCAAGC
TGATCACGGGGGGAGAGCGTGCGCAGCTCGGCGGCGATCTCAACGGCGGCTACTACGTGGCGCCGACGATCTTCACGGGC
AACAACAAGATGCGCATCTTCCAGGAGGAGATCTTCGGCCCGGTCGTGGCGGTCACGTCGTTCAGCGACTACGACGACGC
CATCTCGATCGCCAATGACACGCTCTACGGTCTGGGTGCCGGTGTGTGGAGCCGCGACGGCAACATCGCCTACCGCGCGG
GCCGCGACATCAAGGCCGGCCGGGTGTGGACCAACTGCTACCACCAGTACCCCGCGCACGCCGCGTTCGGTGGCTACAAG
CAGTCCGGCATCGGGCGTGAGACCCACAAGATGATGCTCGACCACTACCAGCAGACCAAGAACCTGCTGGTTTCGTACAG
CAACAAGGCCCAGGGATTCTTCTGA

Protein sequence :
MSEQEKAMTVYARPGADGAKMSFQARYDNYIGGEWVAPVEGRYFENPTPVTGQVFCEVARSSEADIDKALDAAHAAAPAW
GKTAPAERALILNRIADRMEENLESIALAESWDNGKPIRETLNADIPLAIDHFRYFAGVLRAQEGSLSQIDEDTVAYHFH
EPLGVVGQIIPWNFPILMAVWKLAPALAAGNAVVLKPAEQTPVSVLYLFSLIGDLLPAGVVNIVNGFGVEAGKPLASSNR
IAKIAFTGETTTGRLIMQYASQNLIPVTLELGGKSPNIFFNNVLAQADDYQDKALEGFTMFALNQGEVCTCPSRSLIQSD
IFDEFLELAAIRTKAVRQGDPLDTETMIGAQASNDQLEKILSYIEIGKSEGAKLITGGERAQLGGDLNGGYYVAPTIFTG
NNKMRIFQEEIFGPVVAVTSFSDYDDAISIANDTLYGLGAGVWSRDGNIAYRAGRDIKAGRVWTNCYHQYPAHAAFGGYK
QSGIGRETHKMMLDHYQQTKNLLVSYSNKAQGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-144 62
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-152 61
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-152 61
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-152 61
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-151 61
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 4e-69 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MSMEG_1543 YP_885925.1 eptc-inducible aldehyde dehydrogenase VFG0082 Protein 3e-144 62