Gene Information

Name : MSMEG_1306 (MSMEG_1306)
Accession : YP_885696.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_008596
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 1398000 - 1399523 bp
Length : 1524 bp
Strand : -
Note : identified by match to protein family HMM PF00171

DNA sequence :
ATGACCCGCTACTCCGCACCCGGCACCACCGGAAGTGTCGTGACCTTCGCCGACCGCTATGAGCACTTCATCGGAGGAGA
GTTCGTCGCGCCGGCCAAAGGCGAGTACTTCGAGAACGAATCCCCGGTCAACGGTGTCGTGTTCACCGAGGCCGCACGAG
GCACGGCCGACGACATCGAACGCGCACTCGACGCCGCCGAAGCGGCCGCCACCACATGGGGCCGCACCTCACCGTCCGAA
CGGGCCGCGGTGCTGCTGAAGATCGCCGACCGGATGGAAGCCGACCTGGAGAAGCTCGCCGTTGCCGAATCCTGGGACAA
CGGCAAGCCCGTGCGTGAGACCCTCGCGGCCGACCTCCCCCTGGCCATCGACCACCTGCGCTACTTCGCCGGAGCGATCC
GCGCCCAGGAAGGTGGCCTCTCCCAGATCGACGACGACACGGTCGCCTACCACTTCCACGAACCGTTCGGCGTGGTGGGT
TTGATCATCCCGTGGAATTTCCCTCTGCTGCTGGCGATGTGGAAGCTCGCACCGGCACTTGCGGCCGGCAACACCGTCGT
CCTCAAACCTGCAGAGCAGACACCGGCTTCGATCCACGTGCTGCTCGAACTGATCGCCGACGTGGTTCCCGCGGGTGTGA
TCAATGTGGTCACCGGATTCGGACTCGAAGCCGGCAAGCCGCTCGCCGGTAGTCCCCGCATCGCCAAAGTGTCGTTCACC
GGTGAGACCAGCACGGGCCGCGCCATCATGCAATACGCCTCGCAGAACCTGATTCCCGTGACGCTGGAGTTGGGCGGCAA
GAGCCCCAACATCTTCTTCGCCGACGTCGCCGACACGAACGACGACTTCTACGATCGCACGCTGGAGGGCTTCACCATGT
TCGCCCTCAACCAGGGCGAAACCTGCACCTGTCCGTCGCGTGCTTTGATCCAGGCCGACATCTACGACGAGTTCCTCCAA
CGGGCGGTGGCGCGCGTCGGAAAGATCGTCCAGGGCAACCCGCTGGACACCGCCACGATGATCGGGGCCCAAGCGTCACG
CACGCAGTTCGAGAAGATCGTGCAGTACTTCGAGATCGCGAAAGACGAAGGGGCCGTGGTCCGTACGGGCGGGCAGGCCG
CCACCGTGGACGCCGACATCGCGGGCGGGTACTACATCGAGCCCACCATCATCGAAGGGTCGAACTCGATGCGGGTGTTC
CAGGAGGAGATCTTCGGTCCGGTGGTGTGTGCGACGTCGTTCGACCACTATGCCGACGCCATCAAGATCGCCAACGACTC
GCTGTACGGCCTGGCGGGCGGGGTGTGGACCAGAAACGGCACGGTCGCCTATCGCGCGAGCCGGGACATCCAGGCCGGCC
GGATCTTCGTCAACGACTATCACAACTACCCGGCGCACGCGGCGTTCGGCGGTTACAAGCAGTCCGGCATCGGTCGCGAG
AACCACAAGATGATGCTCGAGCACTACCAGCAGACCAAGTGCGTCCTGACCAGTTACGCGACCACCGCGAAGGGCTTCTT
CTGA

Protein sequence :
MTRYSAPGTTGSVVTFADRYEHFIGGEFVAPAKGEYFENESPVNGVVFTEAARGTADDIERALDAAEAAATTWGRTSPSE
RAAVLLKIADRMEADLEKLAVAESWDNGKPVRETLAADLPLAIDHLRYFAGAIRAQEGGLSQIDDDTVAYHFHEPFGVVG
LIIPWNFPLLLAMWKLAPALAAGNTVVLKPAEQTPASIHVLLELIADVVPAGVINVVTGFGLEAGKPLAGSPRIAKVSFT
GETSTGRAIMQYASQNLIPVTLELGGKSPNIFFADVADTNDDFYDRTLEGFTMFALNQGETCTCPSRALIQADIYDEFLQ
RAVARVGKIVQGNPLDTATMIGAQASRTQFEKIVQYFEIAKDEGAVVRTGGQAATVDADIAGGYYIEPTIIEGSNSMRVF
QEEIFGPVVCATSFDHYADAIKIANDSLYGLAGGVWTRNGTVAYRASRDIQAGRIFVNDYHNYPAHAAFGGYKQSGIGRE
NHKMMLEHYQQTKCVLTSYATTAKGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-136 59
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-142 58
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-142 58
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-142 58
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-141 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MSMEG_1306 YP_885696.1 aldehyde dehydrogenase VFG0082 Protein 3e-136 59