Gene Information

Name : MAV_0556 (MAV_0556)
Accession : YP_879836.1
Strain : Mycobacterium avium 104
Genome accession: NC_008595
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 538716 - 541184 bp
Length : 2469 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
ATGCTCAACCACAACTACATCGGCACCGAGCACATCCTGCTGGGTTTGATCCACGAGGGCGAGGGCGTGGCGGCCAAGTC
GCTGGAGTCGCTGGGCATCTCGCTGGAGGGCGTCCGCAGCCAGGTCGAGGAGATCATCGGCCAGGGCCAGCAGGCGCCGT
CCGGACACATCCCGTTCACCCCGCGCGCCAAGAAGGTGCTCGAGCTGAGCCTGCGCGAGGCGCTGCAGCTCGGCCACAAC
TACATCGGCACCGAGCACATTCTGCTGGGCCTGATCCGCGAGGGTGAGGGCGTGGCCGCCCAGGTGCTGGTCAAGCTGGG
CGCCGAGCTGACCCGGGTGCGCCAGCAGGTGATCCAGCTGCTCTCCGGCTACCAGGGTAAGGAGGCCGCCGAGGCCGGCA
CCGGTGGGCGCGGCGGCGAGTCCGGCAGCCCATCCACGTCGTTGGTGCTCGACCAGTTCGGCCGCAACCTGACCGCCGCC
GCGATGGAGGGCAAGCTGGACCCGGTCATCGGCCGCGAGAAGGAAATCGAGCGGGTGATGCAGGTGCTGAGCCGGCGCAC
CAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCGGCAAGACGGCCGTCGTCGAGGGCCTGGCGCAGGCCATCGTGC
ACGGCCAGGTGCCCGAGACGCTGAAGGACAAGCAGCTCTACACCCTGGACCTGGGTTCGCTGGTGGCGGGCTCGCGCTAC
CGCGGTGACTTCGAGGAGCGCCTGAAGAAGGTGCTCAAGGAGATCAACACCCGCGGCGACATCATCCTGTTCATCGACGA
GCTGCACACGCTGGTCGGTGCGGGTGCCGCCGAGGGCGCGATCGACGCGGCCAGCATCCTCAAGCCGAAGCTGGCTCGCG
GCGAGCTGCAGACCATCGGCGCCACCACGCTCGACGAGTACCGCAAGTACATCGAGAAGGACGCCGCGCTGGAGCGTCGG
TTCCAGCCGGTGCAGGTGGGTGAGCCGACGGTGGAGCACACCATCGAGATCCTCAAGGGGCTGCGCGACCGCTACGAGGC
GCACCACCGGGTGTCCATCACCGACTCGGCGATGGTGGCGGCCGCGACGCTGGCGGACCGCTACATCAATGACCGCTACC
TGCCGGACAAGGCGATCGACCTGATCGATGAGGCGGGGGCGCGGATGCGGATCCGCCGGATGACCGCGCCGCCGGACCTG
CGCGAGTTCGACGAGAAGATCGCCGAGGCGCGCCGGGAGAAGGAATCGGCGATAGACGCCCAGGACTTCGAGAAGGCGGC
CAGCCTGCGCGACCGGGAGAAGCAGCTCGTCGCGCAGCGCGCCGAGCGCGAAAAGCAGTGGCGCTCCGGCGACCTCGACG
TGGTCGCCGAGGTGGACGACGAGCAGATCGCCGAGGTGCTGGGCAACTGGACCGGCATCCCGGTGTTCAAGCTGACCGAG
GCCGAGACCACGCGCCTGCTGCGCATGGAGGACGAGCTGCACAAGCGGATCATCGGCCAGGAGGACGCCGTCAAAGCGGT
CTCCAAGGCGATCCGCCGCACCCGCGCCGGGTTGAAGGACCCCAAGCGGCCGTCGGGCTCGTTCATCTTCGCCGGCCCGT
CCGGTGTCGGTAAGACCGAGCTGTCCAAGGCGCTGGCCAACTTCCTGTTCGGCGACGACGACGCGCTCATCCAGATCGAC
ATGGGCGAGTTCCACGACCGGTTCACCGCCTCGCGGCTGTTCGGCGCCCCGCCGGGATACGTCGGCTACGAGGAGGGCGG
CCAGCTCACCGAGAAGGTGCGGCGCAAGCCGTTCTCGGTGGTGCTGTTCGACGAGATCGAGAAGGCTCACCAGGAGATCT
ACAACAGCCTGTTGCAGGTCCTCGAGGACGGCCGGCTCACCGACGGCCAGGGCCGCACGGTCGACTTCAAGAACACCGTG
CTGATCTTCACCTCGAACCTCGGCACGTCCGACATCTCCAAGCCGGTCGGCCTGGGCTTCACCCAGGGTGGCGGTGAGAA
CAACTACGAGCGGATGAAGCAGAAGGTCAACGACGAGCTGAAGAAGCACTTCCGCCCGGAGTTCCTCAACCGCATCGACG
ACATCATCGTCTTCCACCAGCTGACTCGCGACGAGATCATCCGGATGGTCGACCTGATGATCACCCGGGTCGCCGGCCAG
CTCAAGAGCAAGGACATGGACCTGGTGCTCACCGACAAGGCCAAGGCCCTGCTGGCCAAGCGCGGCTTCGACCCGGTGCT
GGGTGCCCGCCCGCTGCGGCGCACCATCCAGCGCGAGATCGAGGACCAGCTCTCCGAGAAGATCCTCTTCGAGGAGGTCG
GGCCCGGTCAGATCGTCACGGTCGACGTCGACAACTGGGACGGCGAAAGCGCCGGCGAGGACGCGGTGTTCACCTTCACC
GGTACCCGCAAGCCGCCGGCCGAGCCGGACCTGGCCAAGGCCGGGGCGCACAGCGCCGACCCGCAGTAG

Protein sequence :
MLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHN
YIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEAAEAGTGGRGGESGSPSTSLVLDQFGRNLTAA
AMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGQVPETLKDKQLYTLDLGSLVAGSRY
RGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERR
FQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRYLPDKAIDLIDEAGARMRIRRMTAPPDL
REFDEKIAEARREKESAIDAQDFEKAASLRDREKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLTE
AETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSKALANFLFGDDDALIQID
MGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDGQGRTVDFKNTV
LIFTSNLGTSDISKPVGLGFTQGGGENNYERMKQKVNDELKKHFRPEFLNRIDDIIVFHQLTRDEIIRMVDLMITRVAGQ
LKSKDMDLVLTDKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQIVTVDVDNWDGESAGEDAVFTFT
GTRKPPAEPDLAKAGAHSADPQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 81

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MAV_0556 YP_879836.1 negative regulator of genetic competence ClpC/mecB VFG0079 Protein 0.0 60
MAV_0556 YP_879836.1 negative regulator of genetic competence ClpC/mecB VFG0080 Protein 8e-148 50