Gene Information

Name : lysS (MAV_0554)
Accession : YP_879834.1
Strain : Mycobacterium avium 104
Genome accession: NC_008595
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 536335 - 537834 bp
Length : 1500 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGAGTCCCGCCCCAGACGCCGACATTCCCGAGCAGTACCGGATCCGCCGGGACAAGCGCGCGCGGCTGCTCGCCGAGGG
GCACGACCCGTACCCGGTCGCCGTCGAACGCACCCACACGCTGGCGCAGGTGCGCGCCGCCCACCCCGACCTGCCCGTCG
ACACCGCGACCGACGACGTGGTCGGCGTCGCCGGCCGGGTGATCTTCGCGCGCAACTCCGGCAAGCTGTGCTTCGCCACG
CTGCAGGAGGGCGACGGCACCACCCTGCAGGTGATGGTCAGCCTGGACAAGGTGGGCCGCGAAGCCCTGGACGCGTGGAA
GGCCGACGTCGACCTGGGCGACATCGTCTCCGTGCACGGCACCCTGATCAGCTCCCGGCGCGGCGAACTGTCCGTGCTCG
CCGACTCGTGGCGGATGGCGTCCAAGTCGTTGCGTCCGCTGCCCGTCGCGCACAAGGAGATGAGCGAAGAGGCGCGGGTG
CGGCAGCGCTACGTCGACCTGATCGTGCGCCCGCAGGCGCGCACGGTCGCCCGGCAGCGGATCGCGGTGATCCGGGCGAT
CCGCAACGCCTTGGAACGGCGCGGGTTTCTCGAAGTCGAAACCCCAATGTTGCAGACGCTGGCCGGGGGCGCGGCTGCAC
GGCCGTTCGTCACCCATTCCAACGCGCTCGACATCGATCTCTACCTGCGGATCGCCCCGGAACTGTTCCTCAAGCGCTGC
GTCGTCGGTGGTTTCGATAAGGTTTTCGAACTAAATCGCGTGTTCCGAAACGAAGGTGCGGATTCCACCCATTCTCCGGA
ATTCTCCATGCTGGAGACCTACCAGGCCTACGGAACGTATGACGATTCGGCGGTGGTGACGCGCGAGCTTATTCAAGAGG
TGGCCGACGAGGCCATCGGAACCCGACAACTACCGCTGCCCGACGGCAGCGTCTACGACATAGACGGAGAATGGGCTTCT
ATAGAAATGTACCCGTCGCTGTCGGCGGCGCTCGGTGAGGAGATCACCCCGCAGACCACGGTGGAAAAGCTGCTCGGCAT
CGCCGAGCGGCTGGGCGTCGAGATCCCCCGCGACCGCGGCTACGGGCACGGCAAGATCGTCGAGGAGCTGTGGGAGCACA
CCGTGGGCGACACGCTCACCGCGCCCACGTTCGTGCGGGATTTCCCGGTCGAGACAACGCCTTTGACGCGTCAGCACCGC
AGCATCGACGGCGTCACCGAGAAATGGGACCTGTACGTGCGTGGGGTCGAGCTGGCCACCGGCTACTCGGAGTTGACCGA
TCCCGTGGTGCAGCGCGAGCGGTTCGCCGCCCAGGCGCGTGCGGCGGCCGCCGGCGACGACGAGGCCATGGTGCTCGACG
AAGACTTTCTCGCCGCGCTCGAGTATGGGATGCCGCCCTGCACCGGAACGGGAATGGGTATCGACCGGTTGTTGATGACA
TTGACCGGGCTGTCAATTCGGGAGACAGTTTTGTTCCCCATCGTTCGGCCGCATTCGTAG

Protein sequence :
MSPAPDADIPEQYRIRRDKRARLLAEGHDPYPVAVERTHTLAQVRAAHPDLPVDTATDDVVGVAGRVIFARNSGKLCFAT
LQEGDGTTLQVMVSLDKVGREALDAWKADVDLGDIVSVHGTLISSRRGELSVLADSWRMASKSLRPLPVAHKEMSEEARV
RQRYVDLIVRPQARTVARQRIAVIRAIRNALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDIDLYLRIAPELFLKRC
VVGGFDKVFELNRVFRNEGADSTHSPEFSMLETYQAYGTYDDSAVVTRELIQEVADEAIGTRQLPLPDGSVYDIDGEWAS
IEMYPSLSAALGEEITPQTTVEKLLGIAERLGVEIPRDRGYGHGKIVEELWEHTVGDTLTAPTFVRDFPVETTPLTRQHR
SIDGVTEKWDLYVRGVELATGYSELTDPVVQRERFAAQARAAAAGDDEAMVLDEDFLAALEYGMPPCTGTGMGIDRLLMT
LTGLSIRETVLFPIVRPHS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 5e-142 64