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Name : leuS (MAV_0055) Accession : YP_879355.1 Strain : Mycobacterium avium 104 Genome accession: NC_008595 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 53575 - 56553 bp Length : 2979 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : GTGCGCAACGCAACCGAGACCAACCTGTGGCCGGCGAAGCCGCCGCGTCGGCCCTTATACCCTGTTCAGGTGACCGAATC CCCGACCACTTCGCCCGCCACCGGCTCCGGTGCCGCCGCGCCGGACTCCGACGCGCCGCCGTATCGCTACACCGCGGCGC TGGCGGGCCGGATCGAGGGCAGCTGGCAGGACACCTGGGCCAAGCTCGGGACGTTCAACGTGCCCAACCCGGTCGGTTCG TTGGCCCCGACGGACGGGACCCCGGTCCCCGAGGACAAGCTGTTCGTGCAGGACATGTTCCCCTACCCGTCGGGGGAGGG GCTGCACGTCGGCCACCCGCTGGGCTACATCGCCACCGACGTATACGCCCGCTACTTCCGGATGACCGGCCGTAACGTGT TGCATGCGTTGGGTTTTGACGCTTTCGGCCTGCCCGCCGAGCAATACGCGGTGCAGACCGGCACCCACCCGCGCACCAGG ACCGAGGCCAACGTGGTCAACTTCCGCCGCCAGCTGGGCCGGCTGGGGCTGGGCCACGACAGCAGGCGCAGCTTCTCCAC CACCGACGTCGAGTTCTACAAGTGGACGCAGTGGATCTTCCTGCAGATCTACAACGCCTGGTTCGACCCCGCCGCCAACA AGGCCCGACCCATCGCCGAGCTGGTCGCCGAATTCGATTCCGGCGCGCGCAGCCTCGACGACGGGCGCAACTGGTCCGAG TTGTCGGCGGGGGAGCGAGCCGACGTGATCGACAGCCACCGGCTGGTCTACCGCGCGGACTCGATGGTCAACTGGTGTCC CGGACTGGGCACCGTGCTGGCCAACGAGGAGGTCACCGCCGACGGGCGCAGCGACCGCGGCAACTTCCCGGTGTTCCGAA AGCGGTTGCGGCAGTGGATGATGCGGATCACCGCCTACTCCGACCGGCTGCTCGACGACCTCGACCTGCTGGACTGGCCG GAGCCGGTGAAGACCATGCAGCGCAACTGGATCGGCCGTTCCACCGGCGCCAAGGCCCTGTTCGCGGCGACCGGCGCCGA CGGCGCGGCGCTCGACATCGAGGTGTTCACCACCCGACCGGACACGCTGTTCGGCGCCACCTATATGGTGCTGGCCCCCG AGCACGAGCTGGTCGACGAGCTGGTCGCGCCCGCCTGGCCGGACGGCACCGACCCGCGCTGGACATACGGCGCCGCCACT CCGGGCGAGGCGGTCGCCGCCTACCGGCGGGCGATCGCCTCGAAGTCGGACCTCGAGCGCCAGGAGAGCAAGGCCAAAAC CGGTGTCTTCCTGGGCAGCTACGCCACCAACCCCACCAATGGCAAGCCGGTTCCGATCTTCATCGCCGACTACGTGCTGG CCGGATACGGCACCGGCGCGATCATGGCAGTGCCCGGCCACGACCAGCGCGACTGGGACTTCGCGCACGAATTCGGCCTG CCCATCGTGGAAGTCATTGCCGGAGGCGATATTTCGGAGGGGGCCTACGCCGGCGACGGGCTATTGGTGAACTCCGGCTA CCTGGACGGACTGGATGTGGCGGCGGCCAAGGAGGCGATCACCGCCCGGCTGGAAGCCGAAGGCCGTGGCTGCGCGCGGG TCGAATTCAAGTTGCGTGACTGGCTTTTCGCCCGGCAACGGTACTGGGGCGAGCCGTTCCCGATCGTCTACGACAGCGAC GGGCGTCCGCATGCCCTCGACGAAGCCGCTCTGCCGGTGGAACTGCCCGACGTGCCGGACTATTCGCCGGTGCTGTTCGA CCCCGACGACGCCGACAGCGAACCGTCGCCACCGTTGGCCAAGGCGACCGACTGGGTGCACGTCGAGCTGGACCTCGGCG ACGGCCTGAAGCCCTACAGCCGCGACACCAACGTGATGCCGCAATGGGCCGGCAGCTCCTGGTACGAACTGCGCTACACC GATCCGCACAACTCGGAACGCTTCTGCGCCAAGGAGAATGAGGCCTACTGGATGGGGCCGCGGCCCGCCGAGCACGGGCC GCAGGATCCCGGCGGCGTCGACCTGTACGTCGGTGGGGCCGAACACGCGGTGTTGCATCTGCTCTACGCCCGGTTCTGGC ACAAGGTGCTCTACGACCTGGGCCACGTCAGCTCCCGCGAGCCGTACCGCCGGCTGGTCAACCAGGGCTACATTCAGGCG TTCGCCTACACCGACTCGCGCGGCTCGTACGTGCCGGCCGAGGAGGTCGTCGAACGCGACGGCCGGTTTTTCTACCGCGG TCCCGACGGGGAGATCGAGGTCTTCCAGGAATTCGGGAAAATCGGGAAGAGCCTGAAGAATTCGATCTCACCCGACGAGA TCTGCGACGACTACGGCGCCGACACGCTGCGGGTCTACGAGATGTCGATGGGCCCGCTGGAGGCGTCCCGCCCCTGGGCG ACCAAGGATGTGGTGGGCGCTCACCGGTTCCTGCAGCGGGTGTGGCGACTGGTCGTCGACGAGCAGACGGGCGAGACGCG GGTGGTCGACGGGGCCGGACGGGATCTGCCCACCGGTACCCTGCGGCTGCTGCACCGCACCATCGCCGGAGTCTCGGAAG ACTATGCGGGACTGCGCAATAACACCGCCGTGGCCAAGTTGATCGAGTACACGAACCATCTCACCAAGGAACATCGCGAC GCGGTGCCCCGCGCGGCGGTCGAGCCGCTGGTGCTGATGCTGGCGCCGTTGGCGCCGCACATGGCCGAGGAGTTGTGGCT GCGGCTGGGCCACACCACCTCGCTGGCGCACGGCCCGTTCCCGGTGGCGGACCCGGCGTACCTCGTCGAGGACACCGTCG AATACCCGGTGCAGGTGAACGGCAAGGTGCGCGGGAGGGTGACGGTGGCGGCCGACGCCGATCGGGACACCCTCGAGGCC GCCGCGCTGGCCGACGAGAAGGTGCTGGCGTTCCTGGCCGGCGCCCAGCCGCGCAAGGTGATCGTGGTCCCGGGCCGGCT GGTCAACCTGGTGGTGTAG Protein sequence : MRNATETNLWPAKPPRRPLYPVQVTESPTTSPATGSGAAAPDSDAPPYRYTAALAGRIEGSWQDTWAKLGTFNVPNPVGS LAPTDGTPVPEDKLFVQDMFPYPSGEGLHVGHPLGYIATDVYARYFRMTGRNVLHALGFDAFGLPAEQYAVQTGTHPRTR TEANVVNFRRQLGRLGLGHDSRRSFSTTDVEFYKWTQWIFLQIYNAWFDPAANKARPIAELVAEFDSGARSLDDGRNWSE LSAGERADVIDSHRLVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYSDRLLDDLDLLDWP EPVKTMQRNWIGRSTGAKALFAATGADGAALDIEVFTTRPDTLFGATYMVLAPEHELVDELVAPAWPDGTDPRWTYGAAT PGEAVAAYRRAIASKSDLERQESKAKTGVFLGSYATNPTNGKPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFAHEFGL PIVEVIAGGDISEGAYAGDGLLVNSGYLDGLDVAAAKEAITARLEAEGRGCARVEFKLRDWLFARQRYWGEPFPIVYDSD GRPHALDEAALPVELPDVPDYSPVLFDPDDADSEPSPPLAKATDWVHVELDLGDGLKPYSRDTNVMPQWAGSSWYELRYT DPHNSERFCAKENEAYWMGPRPAEHGPQDPGGVDLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLVNQGYIQA FAYTDSRGSYVPAEEVVERDGRFFYRGPDGEIEVFQEFGKIGKSLKNSISPDEICDDYGADTLRVYEMSMGPLEASRPWA TKDVVGAHRFLQRVWRLVVDEQTGETRVVDGAGRDLPTGTLRLLHRTIAGVSEDYAGLRNNTAVAKLIEYTNHLTKEHRD AVPRAAVEPLVLMLAPLAPHMAEELWLRLGHTTSLAHGPFPVADPAYLVEDTVEYPVQVNGKVRGRVTVAADADRDTLEA AALADEKVLAFLAGAQPRKVIVVPGRLVNLVV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 4e-149 | 49 |
