Gene Information

Name : thiC (MAV_4731)
Accession : YP_883858.1
Strain : Mycobacterium avium 104
Genome accession: NC_008595
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 4856213 - 4857835 bp
Length : 1623 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGACCGCAATTGTCGAACCGAGCGTGACCACCGGGCCCATCGCGGGCAGCAGCAAGGTCTACCGCGAACTGGACGGGGT
GCCCGGTGCCCGGGTTCCGTTCCGCCGCGTCCACCTGTCCACAGGCGACCACTTCGACCTCTACGACACCTCCGGCCCCT
ACACCGATCCGGACGCGACGATCGACCTGACGGCCGGGCTGCCGGCGCGGCCGGGCCGGGTGCGCGACCGCGGCACCCAG
CTGCAGCGGGCCCGGGCCGGCGAGATCACCGCGGAGATGGCGTTCATCGCCGCCCGCGAGGGCATGCCGGCGGAGTTGGT
GCGCGACGAGGTCGCCCGCGGCCGCGCCGTGATCCCGGCCAACCACAACCATCCCGAGATCGAGCCGATGATCATCGGCA
AGGCATTCGCCACCAAGGTCAACGCGAACATCGGCAACTCGGCGGTGACCAGCTCGATCGCCGAGGAGGTCGACAAGATG
GTGTGGGCCACCCGGTGGGGTGCGGACACCATCATGGACCTGTCCACCGGCAAGAACATCCACGAGACCCGCGAATGGAT
CCTGCGCAATTCGCCGGTGCCGGTCGGCACCGTACCGATCTATCAGGCGCTGGAGAAGGTCAAGGGCGATCCGACCCTGC
TGACCTGGGAGATCTACCGCGACACCGTGATCGAGCAGTGCGAGCAGGGCGTGGACTACATGACCGTGCACGCCGGTGTG
CTGCTGCGCTACGTGCCGCTGACCGCCAAGAGGGTCACCGGCATCGTGTCCCGCGGCGGGTCGATCATGGCCGCCTGGTG
CCTGGCGCATCACCGAGAGTCGTTCCTGTACACCAACTTCGACGAGCTGTGCGAGATCTTCGCCCGCTATGACGTCACCT
TCTCCCTGGGCGACGGCCTGCGGCCCGGCTCGATCGCCGACGCCAACGACGCCGCGCAGTTCGCCGAGCTGCGCACCCTG
GGCGAGCTGACCAAGATCGCGAAATCCCATGGCGTGCAAGTGATGATCGAAGGCCCCGGGCACGTTCCGATGCACAAGAT
CGTCGAGAACGTGCGGCTGGAGGAGGAGTGGTGCGAGGAGGCCCCGTTCTACACGCTGGGTCCGCTGGCCACCGACATCG
CCCCGGCCTACGACCACATCACCTCGGCGATCGGCGCGGCCATCATCGCCCAGGCGGGCACCGCGATGCTGTGCTACGTG
ACCCCGAAGGAGCACCTGGGGCTGCCGGACCGCAAGGACGTCAAGGACGGCGTGATCGCCTACAAGATCGCCGCGCACGC
CGGCGACCTGGCCAAGGGGCACCCGCACGCGCAGGAGCGCGATAATGCGTTGAGCCAGGCGCGTTTCGAGTTCCGCTGGA
ACGACCAGTTCGCGCTGTCGCTGGATCCCGACACCGCGCGGGAGTATCACGACGAGACGCTGCCCGCCGAGCCCGCCAAG
ACCGCGCACTTCTGCTCGATGTGCGGGCCGAAGTTCTGCTCGATGCGCATCACCCAGGACGTCCGCGACTATGCGGCCAA
GCACGGGCTGGACAGCGAGGAAGCGATCGAGGCGGCCATGGCCGACAAGTCTCGCGAGTTCGCCGAGCACGGCAACCGGG
TGTATCTACCGCTGGCACAGTGA

Protein sequence :
MTAIVEPSVTTGPIAGSSKVYRELDGVPGARVPFRRVHLSTGDHFDLYDTSGPYTDPDATIDLTAGLPARPGRVRDRGTQ
LQRARAGEITAEMAFIAAREGMPAELVRDEVARGRAVIPANHNHPEIEPMIIGKAFATKVNANIGNSAVTSSIAEEVDKM
VWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTLLTWEIYRDTVIEQCEQGVDYMTVHAGV
LLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFDELCEIFARYDVTFSLGDGLRPGSIADANDAAQFAELRTL
GELTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEEWCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYV
TPKEHLGLPDRKDVKDGVIAYKIAAHAGDLAKGHPHAQERDNALSQARFEFRWNDQFALSLDPDTAREYHDETLPAEPAK
TAHFCSMCGPKFCSMRITQDVRDYAAKHGLDSEEAIEAAMADKSREFAEHGNRVYLPLAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 3e-158 61
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 3e-158 61