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Name : MAV_4691 (MAV_4691) Accession : YP_883819.1 Strain : Mycobacterium avium 104 Genome accession: NC_008595 Putative virulence/resistance : Virulence Product : eptc-inducible aldehyde dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : 1.2.1.3 Position : 4818420 - 4819943 bp Length : 1524 bp Strand : - Note : identified by match to protein family HMM PF00171 DNA sequence : ATGACTGTCTTCGCACGTCCGGGTTCGGCCGGGGCGTTGATGTCGTACGAATCCCGCTACGACAACTTCATCGGGGGGCA GTGGGTTGCACCGGCGCGCGGGCGCTACTTCGAGAACCCGACACCGGTCACCGGCCAGACGTTCTGCGAGGTGGCCCGCT CGGATGAGGCCGACGTCGACAAGGCGCTCGACGCCGCCCACGCCGCGGCGCCGGCGTGGGGCAAGACCGCGCCGCCGGAG CGGGCCGCGATCCTGAACAAGATCGCCGACCGCATCGAGGAGAACCTGGAATCCCTCGCGGTGGCCGAGGTGTGGGACAA CGGCAAGCCGATCCGCGAGGCGCTGGCCGCCGACATCCCGTTGGCGGCCGACCATTTCCGGTACTTCGCCGGGGCGCTGC GCGCGCAGGAGGGCTCGCTGAGCCAGATCGACGACGACACCGTGGCCTACCACTTCCACGAGCCGCTCGGCGTGGTCGGG CAGATCATCCCGTGGAACTTCCCGATCCTGATGGGTGCCTGGAAATTGGCGCCCGCGCTGGCGGCCGGCAACGCCGTCGT GCTCAAACCCGCGGAGCAGACCCCGGTTTCGGTGCTCTACCTGATGTCGCTGATCGGCGACCTGCTGCCGCCCGGAGTCG TCAACGTGGTCAACGGATTCGGCGCCGAGGCCGGCAAGCCGCTGGCGTCGAGCAACCGAATCGCCAAGATCGCCTTCACC GGCGAGACCACCACCGGGCGGCTGATCATGCAGTACGCCAGCCAGAACCTGATCCCGGTCACCCTGGAGCTCGGCGGCAA GAGCCCCAACATCTTCTTCTCCGACGTGATGGCCAAGGCCGACGACTACCAGGACAAGGCGCTCGAGGGCTTCACCATGT TCGCCCTCAACCAGGGCGAGGTGTGCACCTGCCCGTCGCGCAGCCTGATCCAGGCCGACATCTACGACGAGTTCCTGGAG CTGGCCGCGATCCGCACCAAGGCGGTCCGCCAGGGCGACCCGCTGGATTCCGAGACCATGCTGGGCTCGCAGGCGTCCAA CGATCAGCTGGAAAAGGTGTTGTCCTACATCGCAATCGGCAAGGACGAAGGCGCCACGATCATCACCGGCGGGGAACGCG CCGAACTGGGCGGCGACCTGTCCGGCGGCTTCTACATGCAGCCCACCATCTTCGCCGGCAACAACAAGATGCGCATCTTC CAGGAGGAGATCTTCGGGCCGGTGGTGGCGGTGACGTCGTTCACCGATTACGACGACGCCATCTCCATCGCCAACGACAC CCTGTACGGGCTGGGCGCGGGCGTGTGGTCCCGAGACGGCAACACCGCCTATCGCGCCGGCCGCGACATCCAGGCCGGCC GGGTGTGGGTGAACTGCTATCACGCCTATCCGGCGCACGCGGCGTTCGGCGGCTACAAGCAGTCCGGCATCGGCCGGGAG AACCACAAGATGATGCTCGACCACTACCAGCAGACCAAGAACATGCTGGTGTCCTACAGCAACAAGGCGCAGGGCTTCTT TTAG Protein sequence : MTVFARPGSAGALMSYESRYDNFIGGQWVAPARGRYFENPTPVTGQTFCEVARSDEADVDKALDAAHAAAPAWGKTAPPE RAAILNKIADRIEENLESLAVAEVWDNGKPIREALAADIPLAADHFRYFAGALRAQEGSLSQIDDDTVAYHFHEPLGVVG QIIPWNFPILMGAWKLAPALAAGNAVVLKPAEQTPVSVLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSNRIAKIAFT GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFSDVMAKADDYQDKALEGFTMFALNQGEVCTCPSRSLIQADIYDEFLE LAAIRTKAVRQGDPLDSETMLGSQASNDQLEKVLSYIAIGKDEGATIITGGERAELGGDLSGGFYMQPTIFAGNNKMRIF QEEIFGPVVAVTSFTDYDDAISIANDTLYGLGAGVWSRDGNTAYRAGRDIQAGRVWVNCYHAYPAHAAFGGYKQSGIGRE NHKMMLDHYQQTKNMLVSYSNKAQGFF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 7e-141 | 61 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 8e-148 | 60 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 8e-148 | 60 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 8e-148 | 60 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 4e-147 | 60 |
| ORF SG19 | AAN62241.1 | putative aldehyde dehydrogenase | Not tested | PAGI-3(SG) | Protein | 2e-67 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| MAV_4691 | YP_883819.1 | eptc-inducible aldehyde dehydrogenase | VFG0082 | Protein | 3e-141 | 61 |
