Gene Information

Name : nrdF (MAV_3913)
Accession : YP_883075.1
Strain : Mycobacterium avium 104
Genome accession: NC_008595
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 4041784 - 4042758 bp
Length : 975 bp
Strand : -
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
GTGAGCGAAAACATGAAGCTGATTGACCGCCTTTCGGCGATCAACTGGAACCGGCTGCAAGACGACAAGGACGCCGAGGT
GTGGGACCGCCTGACCGGCAACTTCTGGCTGCCCGAGAAGGTGCCGGTGTCCAACGACCTGCAGTCGTGGGCCACCCTGA
CCGCCCACGAGAAGCAGATGACCATGCGGGTGTTCACCGGCCTGACGCTGCTGGACACCATCCAGGGCACGGTCGGCGCG
GTCAGCCTAATCCCCGATGCGCTGACCCCGCACGAGGAGGCCGTCTACACCAACATCGCCTTCATGGAGTCGGTGCACGC
GCGCAGCTACAGCAACATCTTCTCCACACTGTGTTCGACCGCCGAGATCGATGACGCGTTCCGCTGGTCGGAGGAGAACC
CCAACCTGCAGCGCAAGGCCGAGATCGTGATGCAGTACTACAAGGGCGACGAGCCGCTCAAGCGCAAGGTCGCCTCCACG
CTGCTGGAGAGCTTCCTGTTCTACTCCGGCTTCTACCTGCCGATGTACTGGTCGAGCCGGGCCAAGCTGACCAACACCGC
CGACATGATCCGGCTGATCATCCGCGACGAGGCCGTGCACGGCTACTACATCGGCTACAAGTACCAGCGCGGCCTGGCGC
TGGTCGACGACGCCAAACGTCAAGAGCTCAAGGACTATACGTACGAATTGCTGTTCGAGCTCTACGACAACGAGGTGGAG
TACACGCAGGATCTCTACGACGAGGTGGGGCTGACCGAGGACGTCAAGAAGTTCCTGCGCTACAACGCCAACAAGGCGCT
GATGAACCTCGGCTACGAGGCGCTGTTCCCGCGCGACGAGACCGACGTGAACCCGGCGATCCTGTCGGCGCTGTCGCCCA
ACGCCGACGAGAACCACGACTTCTTCTCCGGCTCGGGCTCGTCCTACGTGATCGGCAAGGCCGTCGTCACCGAGGATGAG
GACTGGGACTTCTAG

Protein sequence :
MSENMKLIDRLSAINWNRLQDDKDAEVWDRLTGNFWLPEKVPVSNDLQSWATLTAHEKQMTMRVFTGLTLLDTIQGTVGA
VSLIPDALTPHEEAVYTNIAFMESVHARSYSNIFSTLCSTAEIDDAFRWSEENPNLQRKAEIVMQYYKGDEPLKRKVAST
LLESFLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKYQRGLALVDDAKRQELKDYTYELLFELYDNEVE
YTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAILSALSPNADENHDFFSGSGSSYVIGKAVVTEDE
DWDF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 2e-113 75