Gene Information

Name : trpE (MAV_3177)
Accession : YP_882360.1
Strain : Mycobacterium avium 104
Genome accession: NC_008595
Putative virulence/resistance : Unknown
Product : anthranilate synthase component I
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0147
EC number : 4.1.3.27
Position : 3271173 - 3272705 bp
Length : 1533 bp
Strand : -
Note : with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine

DNA sequence :
GTGCACGCCCACCTCGCCGCGACGACCTCACGAGAGGATTTCCGCCAGCTGGCGGCCGAGCACCGCGTGGTCCCGGTGAC
CCGCAAGGTGCTGGCCGACAGCGAGACGCCGCTGTCGGCCTACCGCAAACTCGCCGCCAACCGCCCGGGCACCTTCCTGC
TGGAGTCGGCCGAGCACGGCCGGTCCTGGTCGCGGTGGTCGTTCATCGGCGCCGGGTCGCCGTCGGCGCTGACCGTGCGC
GACGGGGAAGCCGGCTGGCTGGGGGTGGTGCCGCAGGACGCACCGACCGGCGGCGATCCGCTGCAGGCACTGCGCGCCAC
CCTGGACCTGCTGGCCACCGGGCCGCTGAGCGGGCTGCCGCCGTTGTCGGGCGGCATGGTCGGCTTCTTCGCCTACGACC
TGGTGCGGCGCCTGGAGCGGCTGCCCGAGCTGGCCGTCGACGACCTGGGCCTGCCGGACATGCTGCTGCTGCTGGCCACC
GATCTGGCGGCCGTCGACCACCACGAGGGCACCATCACGCTGATCGCCAACGCGGTGAACTGGAACGGGACCGACGAACG
GGTCGACGAGGCCTACGACGACGCCGTCGCCCGGCTGGACGTGATGACCGCGGCGCTGGGCCAGCCGCTGGCCTCCACCG
TAGCCACCTTCGAGCGGCCCGAGCCGCGCTACCGCGCGCAGCGCAGCGTCGAGGAGTACGGCAAGATCGTCGACTACCTC
GTCGAGCAGATCGCCGCCGGTGAGGCGTTTCAGGTGGTGCCCTCGCAGCGGTTCGAAATGGACACCGACGTCGACCCGAT
CGACGTGTACCGGATGTTGCGGGTCACCAACCCCAGCCCCTACATGTATCTGCTGCATGTACCGAATGATGCTGGGGGAA
CGGACTTTTCAATCGTCGGGTCCAGCCCGGAGGCTCTGGTCACGGTGGCCGACGGCGTCGCGACCACCCACCCGATCGCC
GGGACCCGGTGGCGCGGGCAGACCGACGAAGAGGACCAGCTGCTGGAAAAGGAGCTGCTGGCCGACGAGAAGGAACGCGC
CGAGCATCTGATGCTGGTCGATCTGGGCCGCAACGATCTGGGCCGGGTGTGCGCGCCGGGCACCGTCCGGGTCGACGACT
ACAGCCACATCGAGCGCTACAGCCACGTCATGCATCTGGTCTCGACGGTGACCGGCGTGCTCGACGCGGGCAGGACCGCC
CTGGACGCGGTGACGGCCTGCTTCCCGGCCGGCACCCTATCGGGTGCGCCGAAGGTGCGGGCGATGGAGCTGATCGAAGA
GGTGGAGAAGACGCGCCGCGGCCTCTACGGCGGCGTGGTCGGCTACCTGGACTTCGCCGGCAACGCCGACTTCGCCATCG
CCATCCGCACGGCGCTGATGCGTGGCGGCACCGCCTACGTGCAATCGGGTGGCGGGGTGGTGGCGGACTCCAACGGCCCC
TACGAATACACGGAGGCCACCAACAAGGCGCGCGCGGTGCTCGGCGCGATCGCGGCCGCCGAGACGCTGACCGAACCGGG
CGCGCGGCGATGA

Protein sequence :
MHAHLAATTSREDFRQLAAEHRVVPVTRKVLADSETPLSAYRKLAANRPGTFLLESAEHGRSWSRWSFIGAGSPSALTVR
DGEAGWLGVVPQDAPTGGDPLQALRATLDLLATGPLSGLPPLSGGMVGFFAYDLVRRLERLPELAVDDLGLPDMLLLLAT
DLAAVDHHEGTITLIANAVNWNGTDERVDEAYDDAVARLDVMTAALGQPLASTVATFERPEPRYRAQRSVEEYGKIVDYL
VEQIAAGEAFQVVPSQRFEMDTDVDPIDVYRMLRVTNPSPYMYLLHVPNDAGGTDFSIVGSSPEALVTVADGVATTHPIA
GTRWRGQTDEEDQLLEKELLADEKERAEHLMLVDLGRNDLGRVCAPGTVRVDDYSHIERYSHVMHLVSTVTGVLDAGRTA
LDAVTACFPAGTLSGAPKVRAMELIEEVEKTRRGLYGGVVGYLDFAGNADFAIAIRTALMRGGTAYVQSGGGVVADSNGP
YEYTEATNKARAVLGAIAAAETLTEPGARR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00338 YP_008207803.1 Anthranilate/para-aminobenzoate synthases component I Not tested AbaR25 Protein 7e-63 44
BJAB0868_00342 YP_008211668.1 Anthranilate/para-aminobenzoate synthases component I Not tested AbaR26 Protein 7e-63 44