Gene Information

Name : pyk (MAV_3170)
Accession : YP_882353.1
Strain : Mycobacterium avium 104
Genome accession: NC_008595
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 3264144 - 3265499 bp
Length : 1356 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
TTGGCGCTGGTCGAGGCCGGAATGGACGTCGCCCGACTGAACTTCAGCCACGGCGACTACGCCGACCACAAAGCCGCCTA
CGAACGGGTGCGGGTGGCCTCCGACGCCACCGGCCGCGCCGTCGGCGTGCTCGCCGATCTGCAGGGCCCCAAGATCCGCC
TAGGGCGCTTTGCCACCGGGCCCACCTACTGGGCCGACGGCGAAACGGTCCGCATCACCGTCGCCGACTGCGAAGGCAGC
CACGACCGGGTGTCGACCACCTACAAACAACTCGCCCAGGACGCCGCGGTCGGGGACCGGGTCCTGGTCGACGACGGCAA
GGTCGGCCTGGTGGTCGACGGCATCGAGGGCGACGACGTCATCTGCACCGTGGTCGAGGGCGGCCCGGTCAGCAACAACA
AGGGCATCTCGCTGCCCGGCATGAACGTCTCCGCACCGGCCTTGTCCGACAAGGACATCGAGGACCTCACCTTCGCGCTC
GAGCTGGGCGTCGACCTGGTCGCGCTGTCCTTCGTGCGTTCGCCCTCCGACGTCGAGCTGGTGCACGAGGTGATGGACCG
CGTCGGCCGGCGGGTGCCCGTGATCGCCAAACTGGAAAAGCCGGAGGCCGTCGACAACCTGGAAGCCATCGTGCTGGCCT
TCGACGCCATCATGGTGGCCCGCGGCGACCTCGGTGTCGAACTTCCCCTGGAAGAGGTTCCGCTGGTGCAGAAGCGGGCC
ATCCAGATGGCCCGGGAGAACGCCAAACCCGTCATCGTGGCAACCCAGATGCTCGATTCGATGATCGAGAACTCACGGCC
GACCCGGGCCGAGGCCTCCGACGTCGCCAACGCCGTGCTGGACGGCGCGGACGCCGTGATGCTGTCCGGGGAGACCTCGG
TGGGCAAGTACCCGCTGGCGGCCGTGCGGACCATGGCGCGCATCATCTGCGCGGTCGAGGACAACTCCACGGCCGCCCCG
CCGCTCACCCACGTGCCCCGCACCAAACGCGGGGTGATCTCGTATGCGGCCCGCGACATCGGCGAACGCCTGGACGCCAA
GGCGCTGGTCGCGTTCACCCAGTCCGGCGACACCGTCAAGCGGCTGGCGCGGTTGCACACCCCGCTGCCGCTGCTGGCCT
TCACGGCATGGCCGGAGGTGCGCAGCCAGCTGGCCATGACCTGGGGCACCGAGACGTTCATCGTGCCGATGATGACCTCC
ACCGACGGCATGATCCGCCAGGTGGACAAGTCGCTGCTGGAACTCGGTCGGTACCGGCGTGGTGACCTGGTGGTGATCGT
CGCCGGTGCGCCACCTGGCACAGTAGGGTCAACCAACCTGATCCACGTGCACCGGATCGGCGAGGACGACGTCTAG

Protein sequence :
MALVEAGMDVARLNFSHGDYADHKAAYERVRVASDATGRAVGVLADLQGPKIRLGRFATGPTYWADGETVRITVADCEGS
HDRVSTTYKQLAQDAAVGDRVLVDDGKVGLVVDGIEGDDVICTVVEGGPVSNNKGISLPGMNVSAPALSDKDIEDLTFAL
ELGVDLVALSFVRSPSDVELVHEVMDRVGRRVPVIAKLEKPEAVDNLEAIVLAFDAIMVARGDLGVELPLEEVPLVQKRA
IQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKYPLAAVRTMARIICAVEDNSTAAP
PLTHVPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVKRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPMMTS
TDGMIRQVDKSLLELGRYRRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-59 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-59 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-59 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-59 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_882353.1 pyruvate kinase VFG0479 Protein 6e-60 42