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Name : lysS (MAV_3128) Accession : YP_882312.1 Strain : Mycobacterium avium 104 Genome accession: NC_008595 Putative virulence/resistance : Unknown Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 3209782 - 3213009 bp Length : 3228 bp Strand : + Note : catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : GTGATCGCCACGGTGTCGCTGCTGGGCAGCGTGTCCCCGCTGATCCGGTACCTGATCAAGGTCCCGCGCGAGTTCATCAA CGACTACCTGTTCAACTTCCCCGACACCAGCATCGCCTGGTCGTTCGTGCTGGCCCTGCTGGCGGCGGCGCTGACGGCAC GCAAGCGGATCGCCTGGCTGCTGTTGCTGGGCAACATGATCCTGGCCGCCGCCCTCAACGTCGCCGACATCGCCGCCGGT GACAACACCGCGGCCGAGATCTTCGGCGAGAACCTGGGTTTCGCCGTCCACATCGTCGCGATCGTCCTGCTGGTGCTGGC GTATCGGGAGTTCTGGGCCAAGGTCCGCAAGGGCGCGTTGGTCAAGGCGGCCGCGGTGCTGGTCGCCGGGGACGTGGTGG GCATCCTGGTGTCGTGGGGCCTGGTCGAGTTGTTCCCCGGCACCCTGGCCCGCCAGGACCGGCTGCCCTACGTGGTCAAC CGGGTGGTCGGCTTCGCGCTGGCCGACCCGGACCTGTTCACCGGCCGCCCGCACGTGTTCCTCAACGCGATCTTCGGGTT GTTCGGCGCGCTCGCGCTGATCATGGCGACCATCGTGCTCTTTCAATCCCAGCGCGCGGAGAACGCGCTGACCGGTGAGG ACGAGTCGGCCATCCGCGGACTGCTGGAGTTGTACGGCAAGAACGACTCGCTGGGCTACTTCGCCACCCGCCGCGACAAG TCGGTGGTCTTCGCCCAGAGCGGACGCGCCGCCATCACCTACCGGGTCGAGATCGGGGTCTGTTTGGCCAGCGGCGACCC GATCGGCGATCCCCGCGCCTGGCCGCAGGCGGTCGACGCCTGGCTGGGCCTGTGCCAGACCTACGGCTGGGCGCCCGGCG TGATGGGCGCCAGCACGCAGGGGGCTCGGACCTATCGCGAGGCCGGCCTCAACGCGCTCGAGCTGGGTGACGAGGCCATC CTGCGCACCTCCGAGTTCAAGCTGTCCGGCCCGGACATGCGCGGCGTCCGCCAGGCGGTGACCCGGGCCCGCCGCGCCGG GTTGACGGTGCGGATCCGCCGGCACCGCGACATCTCCCCCGAGGCGATGGCCGACACCATCGCCCGCGCCGACGCCTGGC GTGACACCCAGACCGAGCGCGGCTTCTCCATGGCGCTGGGCCGACTCGGTGACCCGGCCGACGGGGACTGCCTGCTGGTG GAGGCCATCGACCGGGACGGCAGCGTGGTCGCGATGCTGTCGCTGGTCCCGTGGGGCACCACCGGTGTGTCGCTGGACTT GATGCGCCGGTCGCCGAGTTCACCCAACGGCACCATCGAGCTGATGGTCAGCGAGCTGGCGTTGAATGCTGAAAGCCTTG GTATCACCCGCATTTCGCTGAACTTCGCGATGTTTCGGTCGGCGTTCGAACAGGGCGCCCAGCTGGGCGCCGGCCCGGTC GCGCGGCTGTGGCGGGGGTTGCTGCTGTTCTTCTCCCGGTGGTGGCAGCTGGAGACCCTGTACCGCTCGAACATGAAGTA CCAACCCGATTGGGTTCCGCGCTACGCCTGCTACGAGGATGCCCGGCTGATCCCCCGGGTCGGCGTCGCGTCGGTGATCG CCGAGGGCTTCCTGGTGTTGCCGTTCAGCCGGCGCGACAAGGTGCACACCGGCCACCACCCCGCCGTGCCGGCCCGGCTG GCGCAGTCGGGCCTGCTGCACCACGACGGCTCGGCACCGGACGTGAGCGGGCTGCGCCCGGAGCGCACCGACGCCGAGGA GGCGCGCTCGCGGCTGCCCGAGCAGGTTAGGGTGCGCCTGGCCAAGCTGAAGGTGTTGCAGCGCAACGGTGTTGACGCCT ATCCGGTGGGCTGTCCGCCCAGCCACACCGTCGCGCAGGCGCTGGACGCCGACGACCAGCAGGACATCACCGTCGCCGGC CGGATCCTGCGGATCCGCGACTTCGGTGGGGTGCTGTTCGCCCAGCTGCGGGACTGGTCGGGGGAAATGCAAGTGCTGCT AGACAATTCGCGTCTGGAGCGGGGCCGCACGGCCGACTTCACCGCGGCCATCGATCTCGGCGACCTGGTCGAGGTGTCCG GTCAGATGGGGTTCTCCAAGAAAGGCACCCGGTCGCTGATCGTCACCGACTGGCGGATGATCGGTAAGTGCTTGCGGCCA TTGCCCAATAAGTGGAAGGGGCTCACCGATCCGGAGGCCCGGGTGCGAACCCGCTACGTCGACCTGGCGGTCAACCCCGA GTCGCGGGAGTTGATCGCGGCGCGCAGCGAGGTGCTGCGCTCGGTCCGGCAGACCCTGTTCGCCAAGGGATTCATCGAGG TCGAGACCCCGATCCTGCAGCAGATCCACGGCGGCGCCACCGCCCGACCGTTCGTCACGCACATCAACACCTACGACATG GACCTGTTCCTGCGCATCGCGCCGGAGCTGTATCTGAAGCGGCTGTGCGTCGGCGGCGTGGAGCGCGTCTTCGAGTTGGG CCGGGCGTTCCGCAACGAGGGGGTCGACTTCAGCCACAACCCGGAATTCACCCTGCTGGAGGCCTACCAGGCGCACGCCG ACTATCGGGTGTGGATCGACGGGTGCCGCGAGCTGATCCAGAACGCCGCCCAGGCCGCGCACGGCGAGCAGACCGTGCTG CGGCCCGGCGCCGACGGCCGGCTGCAACCGGTCGACATCTCCGGGATCTGGGCGGTCAAGACCGTGCACGACGCGGTGTC CGAGGCGCTCGGCGAGCAGGTCGACCCCGGCACGTCGCTGTCCACCCTGCGCAAACTGTCCGACGCGGCGCGCATCCCCT ACCGCGCGCACTGGGACGCCGGCGCGGTGGTGCTCGAGCTCTACGAGCACCTGGTCGAGGACCGGACCGAGGAGCCGACG TTCTACGTCGACTTCCCCACCTCTGTGTCACCGCTGACCCGGCCGCACCGCAGCCGGCCCGGGGTCGCGGAGCGGTGGGA CCTGGTGGCCTGGGGTGTCGAACTGGCCACCGCCTACAGCGAGCTGACCGATCCGGTGGAGCAGCGCCGCCGCCTGCAGG AGCAGTCGCTGTTAGCTGCCGGCGGGGATCCCGAGGCGATGGAACTCGACGAGGACTTCCTGCAGGCGATGGAGTACGCG ATGCCGCCGACGGGCGGGCTGGGCATGGGCGTCGATCGCCTCGTCATGCTCATAACGGGCCGCAGCATCCGCGAAACCTT GCCGTTTCCGCTGGCCAAGCCGCATTAG Protein sequence : MIATVSLLGSVSPLIRYLIKVPREFINDYLFNFPDTSIAWSFVLALLAAALTARKRIAWLLLLGNMILAAALNVADIAAG DNTAAEIFGENLGFAVHIVAIVLLVLAYREFWAKVRKGALVKAAAVLVAGDVVGILVSWGLVELFPGTLARQDRLPYVVN RVVGFALADPDLFTGRPHVFLNAIFGLFGALALIMATIVLFQSQRAENALTGEDESAIRGLLELYGKNDSLGYFATRRDK SVVFAQSGRAAITYRVEIGVCLASGDPIGDPRAWPQAVDAWLGLCQTYGWAPGVMGASTQGARTYREAGLNALELGDEAI LRTSEFKLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISPEAMADTIARADAWRDTQTERGFSMALGRLGDPADGDCLLV EAIDRDGSVVAMLSLVPWGTTGVSLDLMRRSPSSPNGTIELMVSELALNAESLGITRISLNFAMFRSAFEQGAQLGAGPV ARLWRGLLLFFSRWWQLETLYRSNMKYQPDWVPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRDKVHTGHHPAVPARL AQSGLLHHDGSAPDVSGLRPERTDAEEARSRLPEQVRVRLAKLKVLQRNGVDAYPVGCPPSHTVAQALDADDQQDITVAG RILRIRDFGGVLFAQLRDWSGEMQVLLDNSRLERGRTADFTAAIDLGDLVEVSGQMGFSKKGTRSLIVTDWRMIGKCLRP LPNKWKGLTDPEARVRTRYVDLAVNPESRELIAARSEVLRSVRQTLFAKGFIEVETPILQQIHGGATARPFVTHINTYDM DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYRVWIDGCRELIQNAAQAAHGEQTVL RPGADGRLQPVDISGIWAVKTVHDAVSEALGEQVDPGTSLSTLRKLSDAARIPYRAHWDAGAVVLELYEHLVEDRTEEPT FYVDFPTSVSPLTRPHRSRPGVAERWDLVAWGVELATAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYA MPPTGGLGMGVDRLVMLITGRSIRETLPFPLAKPH |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| lysX | YP_003784331.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-161 | 44 |
| lysS1 | YP_005686365.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-161 | 44 |
| lysS1 | YP_005682181.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 4e-161 | 44 |
| lysS1 | YP_005684273.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-161 | 44 |
