Gene Information

Name : tpx (MAV_2770)
Accession : YP_881959.1
Strain : Mycobacterium avium 104
Genome accession: NC_008595
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 2801551 - 2802045 bp
Length : 495 bp
Strand : -
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence :
ATGGCACAGATAACGTTGCGTGGAAACCCGATCAACACCGTCGGCGAGCTGCCCTCCGTCGGCTCCAAGGCCCCGGCCTT
CAGCCTGACGGGCGGCGACCTGAGCCCGGTCACCAGTGATCAATTCAGCGGTAAGCCGTTGGTGCTCAACATCTTTCCGT
CCATCGACACGCCGGTGTGCGCGACCAGCGTGCGCACCTTCAACGAGCGGGCCGCCGGCGCCGGCGCCACCGTGCTGAAC
GTGTCCAAGGACCTGCCGTTCGCGCAGGCGCGATTCTGCGGCGCCGAGGGCATCGAGAACGTCAAGACCGCGTCGGCCTT
CCGGGACAGCTTCGGCGACGACTACGGGGTCACCATCGCCGACGGGCCGATGGCCGGGCTGCTGGCCCGGGCCATCGTGG
TGGTCGGCGCCGACGGCAACGTCGCCTACACCGAGCTGGTGCCCGAGATCGCCCAGGAGCCCAACTACGACGCGGCGCTG
GCCGCGGCGGGCTAG

Protein sequence :
MAQITLRGNPINTVGELPSVGSKAPAFSLTGGDLSPVTSDQFSGKPLVLNIFPSIDTPVCATSVRTFNERAAGAGATVLN
VSKDLPFAQARFCGAEGIENVKTASAFRDSFGDDYGVTIADGPMAGLLARAIVVVGADGNVAYTELVPEIAQEPNYDAAL
AAAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 3e-33 43
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 5e-33 43
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 4e-33 43
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 3e-33 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_881959.1 thiol peroxidase VFG0087 Protein 1e-33 43