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Name : MAV_1203 (MAV_1203) Accession : YP_880449.1 Strain : Mycobacterium avium 104 Genome accession: NC_008595 Putative virulence/resistance : Resistance Product : cystathionine gamma-synthase Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0626 EC number : 2.5.1.48 Position : 1150063 - 1151229 bp Length : 1167 bp Strand : + Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine DNA sequence : ATGAGCGACGACGGCAACGCACACCCCGAGTTCAGCGGACTGGCCACCAAGGCGATTCACGCCGGCTACCGGCCGGACCC GGCGACCGGAGCGGTCAACACGCCGATCTACGCCAGCAGCACCTTCGCCCAGGACGGGGTGGGCGCGCTGCGCGGCGGGT ACGAGTACGCCCGCACCGGCAACCCGACCCGGGCCGCGCTGGAGGCCACGCTGGCCGCGGTGGAGGCCGGCAGCCACGGG CGGGCCTTCGCCTCCGGCATGGCCGCCACCGACTGCGCGCTGCGGGCGGTGCTGCGGCCCGGCGACCACGTGGTGATCCC GAATGACGCCTACGGCGGCACCTTTCGGTTGATCGACAAGGTGTTCACCCGCTGGAACGTCGAATACACGCCGGTGCCGT TGCATCAGCTCGACGCCGTGGCCGCCGCGATCACGCCGCGCACCCGGCTGATCTGGGTGGAAACCCCGACCAACCCGTTG CTGTCGATCGCCGACATCGCCGCGCTGGCCCAGCTGGGCCACCAGCACTCGGCAAAGGTGTTGGTGGACAACACCTTTGC CTCGCCGGCGCTGCAGCAGCCGTTGACGCTGGGCGCCGACATCGTGCTGCATTCCACCACCAAGTACATCGGCGGGCACT CCGACGTGGTGGGCGGTGCGCTGGTCACCAACGACGCCGAGCTGGACGACGCGTTCGGGTTCTTACAGAACGGGGCGGGC GCGGTGCCCGGCCCGTTCGACGCCTACCTGACCATGCGCGGGCTGAAGACGCTGGTGCTGCGGATGCAGCGGCACACCGA AAACGCCTCTGCCGTAGCGCAATTCCTCGCCGGGCACCCCGCGGTGAGCGCGGTGCTCTATCCCGGCCTGCCCGGCCATC CGGGCCACGACGTCGCCGCCCGGCAGATGTCGGGCTTCGGCGGCATGGTCTCGGTGCGGATGCGCGGCGGCCGGCAGGCC GCCCGAAAGCTGTGCGCCAACACCCGGGTGTTCATCCTGGCCGAGTCGCTGGGCGGGGTCGAGTCGCTGATCGAGCACCC CAGCGCGATGACGCACGCGTCGACGGCGGGGTCGCAACTGGAGGTGCCCGACGATCTGGTGCGGCTGTCGGTCGGCATCG AGGACGTCGACGACCTGCTGGCCGACCTCGATCGGGCGCTCAGTTGA Protein sequence : MSDDGNAHPEFSGLATKAIHAGYRPDPATGAVNTPIYASSTFAQDGVGALRGGYEYARTGNPTRAALEATLAAVEAGSHG RAFASGMAATDCALRAVLRPGDHVVIPNDAYGGTFRLIDKVFTRWNVEYTPVPLHQLDAVAAAITPRTRLIWVETPTNPL LSIADIAALAQLGHQHSAKVLVDNTFASPALQQPLTLGADIVLHSTTKYIGGHSDVVGGALVTNDAELDDAFGFLQNGAG AVPGPFDAYLTMRGLKTLVLRMQRHTENASAVAQFLAGHPAVSAVLYPGLPGHPGHDVAARQMSGFGGMVSVRMRGGRQA ARKLCANTRVFILAESLGGVESLIEHPSAMTHASTAGSQLEVPDDLVRLSVGIEDVDDLLADLDRALS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAR0460 | YP_039909.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 1e-69 | 47 |
| SAS0418 | YP_042545.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 1e-70 | 47 |
| metB | YP_281510.1 | cystathionine beta-lyase | Not tested | Not named | Protein | 4e-49 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| MAV_1203 | YP_880449.1 | cystathionine gamma-synthase | BAC0207 | Protein | 2e-56 | 43 |
