Gene Information

Name : NT01CX_1473 (NT01CX_1473)
Accession : YP_877554.1
Strain : Clostridium novyi NT
Genome accession: NC_008593
Putative virulence/resistance : Virulence
Product : tetanolysin O
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 643628 - 645430 bp
Length : 1803 bp
Strand : +
Note : identified by match to protein family HMM PF01289

DNA sequence :
ATGGCAGTTTTGAAACTAGACAATAAAACATTAGAATCTAAGAAGAATAACAATGCTATAGTAAAAGAAAGCACAAATGT
TAATAAAAAACTTAATACAGAACCTAATAAAAAACTTAACGCAAAACCCAGTATAGAACCTAATATAAAACAAAACATTA
TACCTAAAGTTACATGTGATGAAAAGTCTGAAAAATCAGAACAAGGTTTATTATCAAGCTTAAAATCAGATAATAAAAAA
TTTAGAAAAATATCTAGAATACCACAACTAGAAAAGAAATCTAAATTAACTAAATTAGTAACTAATAAATATTTGTTAGA
TACTACATTTAGTAATTATACTGTACCTTATGGTGAAATAATGCCAACAAGTGTAGGAGCACTTGAGGATGAAAACCCCA
ATGGTAATGAAATTGATGATGCTATTTATGATTTGAAATATGATCCTCGTAAAATTTTAGCCTTTAATGGTGAAGCTGTA
GAAAACTTTACACCAGCAGAAGGTTTTGAAAATCCAGATAAATATATAGTAATAAAGCGTGAAAAGAAAAGCATATCAGA
TTCAACAGCAGACATATCAGTTATAGATTCTATAAATGATAGAACATATCCAGGTGCAATACAACTTGCAAATAGAAATC
TTGTAGAAAACAAGCCAGATATAATTTCATGCAAGAGAAAGCCAATAACTATAAGTGTTGACCTTCCGGGTATGGCTGAT
GATGGCAGAAAAGTAGTTACATCGCCAACATATTCTTCAGTTAAATCAGCTGTTAATTCTTTATTAGATGAATGGAATAC
TAAATATTCATCAAAATATGCTATTCCTGCTAGGGTTAGTTATAGTGATTCTATGGTGTATAGTAAATCACAATTATCTA
CTGCATTTGGATGTAATTTTAAAGCTTTAGATAAAGCATTAAATATAGATTTTAATTCTATATATAAAGGTGAAAAGCAA
GTAATGCTTCTTGCGTATAAACAAATATTTTATACTGTAAGTGTAGATGCACCAGAAAATCCTTCAGATTTATTTGATGA
TAGTGTAACACTTAAACAATTAAAGGCAAAAGGATTAAATAAGGACAATCCACCTGCATATGTTTCTAATGTTGCTTATG
GAAGAACTATATATGTTAAGTTAGAAACTACTTCTAAGAGTTTAAATGTAAAAGCTGCTTTTAAAGCATTAATTAAAAAT
CAAGATATAAGTGGAAATACAGAATATAAAGACATATTAAATCAAAGTTCTTTTACTGCTACTGTTTTAGGTGGTGGAGC
TAAAGAGCACAATAAAGTAATAACTAAGAATTTTGATGAGATAAGAGAAGTTATAAAAAATAATGCAGAATATAGTCCTA
GAAATCCAGGATACCCTATATCATATACAACTACATTCTTAAAAGATAATGCAGTTGCAACTATTAATAGCAAAACAGAT
TATATAGAAACTACAGCTACAGAATACACTAATGGAAAATTAGTACTTGATCATAAAGGTGGATATGTTGCTCAGTATGA
TATAAGCTGGGATGAAGTTAATTATGATAAGAATGGTAAAGAAATAGTTACTCACAAAACTTGGGATGGAAACTATAAGG
ATAGAACAAGTCATTTTAACACTGAAATATATCTAAAAGGAAATTCTAGAAATATTAATGTTAAAGTTAGAGAGTGCACA
GGGCTTGCATGGGAATGGTGGAGAACTATAATAGATGATAAAAATTTACCTTTAGTTAAGAAAAGAACTATTAACATATG
GGGTACAACATTATATCCACGTCATTCAGTAGAAATTCAATAA

Protein sequence :
MAVLKLDNKTLESKKNNNAIVKESTNVNKKLNTEPNKKLNAKPSIEPNIKQNIIPKVTCDEKSEKSEQGLLSSLKSDNKK
FRKISRIPQLEKKSKLTKLVTNKYLLDTTFSNYTVPYGEIMPTSVGALEDENPNGNEIDDAIYDLKYDPRKILAFNGEAV
ENFTPAEGFENPDKYIVIKREKKSISDSTADISVIDSINDRTYPGAIQLANRNLVENKPDIISCKRKPITISVDLPGMAD
DGRKVVTSPTYSSVKSAVNSLLDEWNTKYSSKYAIPARVSYSDSMVYSKSQLSTAFGCNFKALDKALNIDFNSIYKGEKQ
VMLLAYKQIFYTVSVDAPENPSDLFDDSVTLKQLKAKGLNKDNPPAYVSNVAYGRTIYVKLETTSKSLNVKAAFKALIKN
QDISGNTEYKDILNQSSFTATVLGGGAKEHNKVITKNFDEIREVIKNNAEYSPRNPGYPISYTTTFLKDNAVATINSKTD
YIETTATEYTNGKLVLDHKGGYVAQYDISWDEVNYDKNGKEIVTHKTWDGNYKDRTSHFNTEIYLKGNSRNINVKVRECT
GLAWEWWRTIIDDKNLPLVKKRTINIWGTTLYPRHSVEIQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
slo YP_281505.1 streptolysin O Virulence Not named Protein 6e-134 56
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 5e-125 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NT01CX_1473 YP_877554.1 tetanolysin O VFG2275 Protein 1e-144 60
NT01CX_1473 YP_877554.1 tetanolysin O VFG0976 Protein 2e-134 57
NT01CX_1473 YP_877554.1 tetanolysin O VFG0074 Protein 4e-125 50
NT01CX_1473 YP_877554.1 tetanolysin O VFG1363 Protein 4e-116 49