Gene Information

Name : NT01CX_1087 (NT01CX_1087)
Accession : YP_877171.1
Strain : Clostridium novyi NT
Genome accession: NC_008593
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence clpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 204994 - 207435 bp
Length : 2442 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861

DNA sequence :
ATGATATTTGGAAGATTTACAGAAAGAGCGCAGAATATTCTTTACTATGCAAAGCAAGCAGCACAAGAATTTAGGCATGG
ATATATTGGAACTGAACATATATTGCTTGGACTTTTAAAAGAAGATAAGGGAATGTCCAAAAATCTTTTAAATGATATGA
ATGTAAATGAAGAAAATGTTAAGAATTTAATTGCCCAATATGAATCTTTTGGAGAATTTGAATTAAATCAAAAAGAGATA
CCGCTAACTCCAAGAACAAAAAGATTATTGGAGCTTAGTTTACTTGAGGCAAGGGATAAAGGACATAATTATATTACTCC
TGAACATATGCTTTTAGCTTTAATAAAAAAGGAAGACGGACTTGCTTATACTATACTAAATGATTTAGGAGTTAACTTTG
AAAAACTTGAAGCCCAACTAGAAAATGATCCTAATTTGAAACAAGGAAAACAAGTTTCAGGAGAAAGTAATGAAAGAGTG
TCTCATAATACACCTACTTTAGATAAGCATGGTCGTGATTTAACTAAGATGGCTGAGGAAGGAAAACTAGATCCTGTAAT
AGGTAGAGGTGCTGAAACGGAAAGAGTCCTTGAGATTTTATGTAGAAGAATTAAAAATAATCCTTGCTTAATAGGAGATC
CTGGAGTTGGAAAAACTGCTATTGCTGAAGGACTTGCACAAAAGATAGTGCAAGGTAATATACCAGAAATACTCAAAAAT
AAAAGAGTTATAGCACTAGACATATCATCTATGGTAGCTGGTTCTAAGTATAGAGGTGAATTTGAAGAAAGAGTTAAGAA
AATAATGGATGAAATATACAAAGACAAAAATGTAATTTTATTTATTGATGAAATTCACACTATAGTAGGAGCTGGTGGAG
CTGAAGGGGCCATTGATGCTTCTAATATATTAAAACCTGCACTTGCAAGAGGTGAAATTCAATGCATAGGAGCTACAACT
ATAGATGAATATAGAAAATATATAGAAAAGGATTCTGCACTGGAGAGAAGATTTCAACCAGTTAATGTAGGAGAGCCTAC
AAAGGAAGAATCTATAGAAATATTAAAGGGACTTAGAGATAAGTATGAAGCTCATCATGGAGTTAAAATAACAGATGATG
CAATAGTTGCAGCAGTTGAACTTTCAGATAGGTATATAACAGATAGATTTCTACCAGATAAAGCTATAGATTTAATAGAT
GAAGCTGGTGCGAAGGTTAGAATAAAAAATCTAACAGCCCCACCAAGTTTAAAAGACATGGAAGCAGAACTTGAGAAGGT
TGTTAAGGAAAAAGAAGATGCTGTTATAGTTCAAGATTTTGAGAAAGCTGCATCTTTGAGAGATAAGGAGAAAAACTTAA
AGCAACAGTTAAAAGATTTTACTGACAACTGGAAAAAACAAAGCCACATGGTAACTGAAATTGTGTCTGAAGATCAAATA
GCTGAGGTAGTATCTACTTGGAGCAATGTGCCAGTTGAAAAATTGACAGAAAAAGAAGCAGATAGATTATTAAAATTAGA
AGAAACTCTTCACAAAAGGGTAATTGGTCAAAATGAAGCAGTTAAATCCATAGCAAGAGCTGTAAGACGTGCGAGAGTTG
GACTTAAAGATTCTAAAAGACCAATAGGTTCATTTATATTTTTAGGACCTACTGGAGTTGGAAAGACAGAGCTATCAAAG
GCACTTGCAGAAGCTATGTTTGGTGATGAAAATAATATGATAAGAATTGATATGTCAGAATACATGGAGAAACATGCAGT
TTCAAGACTTGTTGGTTCTCCTCCAGGATATGTAGGACATGATGAGGGTGGACAATTAACAGAACAAGTAAGACGTCATC
CTTATTCAGTAATTTTATTTGATGAAATTGAAAAAGCTCATCCAGAGGTATTTAACATACTACTTCAAATTTTAGAAGAT
GGAAGACTTACTGATTCAAAAGGAAAGACTGTTGATTTTAAAAATACAATAATAATATTAACTTCAAATGTAGGTGCTTC
AAGAATAAATAAGCAAAATACTTTAGGATTTTCAAGAAGTGAAGATGAAGCGGAAGATGAATATGAAAAGATGAAAGATA
ATGTAATGGAAGAATTAAAAAATAGTTTTAGACCAGAATTTTTAAATAGAATTGACGATATTATTGTATTCCATTCATTA
GATGAAGAAAACTTAAAGGAAATAGTTAAACTTATGCTAGATGAAGTATCAAATAGATTAAAAGATAAAGATATATATAT
TGATTTTGATGATGAAACAGAAAAGCTTCTAGTTAAAAAAGGTATAGATGTAACTTATGGTGCAAGACCATTAAGAAGAA
CTATAACAAGAATAATAGAAGATAAATTATCAGAAGAAATATTAAAGGGTGTTATAAAAAAAGGCGATAAAGTATATACT
ACAGTTGAAAATAATGAGTTAATATTTAAGAAAATCAACTAA

Protein sequence :
MIFGRFTERAQNILYYAKQAAQEFRHGYIGTEHILLGLLKEDKGMSKNLLNDMNVNEENVKNLIAQYESFGEFELNQKEI
PLTPRTKRLLELSLLEARDKGHNYITPEHMLLALIKKEDGLAYTILNDLGVNFEKLEAQLENDPNLKQGKQVSGESNERV
SHNTPTLDKHGRDLTKMAEEGKLDPVIGRGAETERVLEILCRRIKNNPCLIGDPGVGKTAIAEGLAQKIVQGNIPEILKN
KRVIALDISSMVAGSKYRGEFEERVKKIMDEIYKDKNVILFIDEIHTIVGAGGAEGAIDASNILKPALARGEIQCIGATT
IDEYRKYIEKDSALERRFQPVNVGEPTKEESIEILKGLRDKYEAHHGVKITDDAIVAAVELSDRYITDRFLPDKAIDLID
EAGAKVRIKNLTAPPSLKDMEAELEKVVKEKEDAVIVQDFEKAASLRDKEKNLKQQLKDFTDNWKKQSHMVTEIVSEDQI
AEVVSTWSNVPVEKLTEKEADRLLKLEETLHKRVIGQNEAVKSIARAVRRARVGLKDSKRPIGSFIFLGPTGVGKTELSK
ALAEAMFGDENNMIRIDMSEYMEKHAVSRLVGSPPGYVGHDEGGQLTEQVRRHPYSVILFDEIEKAHPEVFNILLQILED
GRLTDSKGKTVDFKNTIIILTSNVGASRINKQNTLGFSRSEDEAEDEYEKMKDNVMEELKNSFRPEFLNRIDDIIVFHSL
DEENLKEIVKLMLDEVSNRLKDKDIYIDFDDETEKLLVKKGIDVTYGARPLRRTITRIIEDKLSEEILKGVIKKGDKVYT
TVENNELIFKKIN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NT01CX_1087 YP_877171.1 negative regulator of genetic competence clpC/mecB VFG0079 Protein 0.0 58
NT01CX_1087 YP_877171.1 negative regulator of genetic competence clpC/mecB VFG0080 Protein 5e-153 50