Gene Information

Name : NT01CX_0220 (NT01CX_0220)
Accession : YP_878724.1
Strain : Clostridium novyi NT
Genome accession: NC_008593
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence clpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1885424 - 1887721 bp
Length : 2298 bp
Strand : -
Note : identified by match to protein family HMM PF00004

DNA sequence :
ATGGAAATGTGTTCCATTTGCAAAAAGAATATAGCAACTATATACACAGCAAAGATAGAAGATGGAAAAACAAAAATGGT
TGGAATATGTTTGGAGTGCGCTAAAAAAATGGGTATGCCCATAATGGATCAATTCATGAAGCAAGCGGGAATAACTTCAG
AAGATATGGATAATCTAACAGAACAGATGAATAAAGTATTTGAAGAGACTAATATAGATGATTTAGCAAATAATAATTTT
CTTACTAATGTTTTAAATGGAATATTTCCTAAAAATGATGAAGAAGATTATGCAGATAATTTAGATTCTCTTGAATTTGA
TAAAGAGAAAACATCAGAGAAAGATAAAACTAATAGTGAAGGTATAAGAACTAAAAACATATTTAAGAATAAGAAAAAGA
CAAAATATTTAAATAAATATGGAATAAATTTAACTGATAAGGCAAAAGAGCATAAGGTTGATAAAGTAGTTGGTAGAAAT
AGAGAAATAGATAGAGTAATTCAAATTTTAAATAGAAGAAATAAAAATAATCCAATATTAATAGGTGAACCAGGTGTAGG
TAAAACAGCTATTGCGGAGGGATTGGCAGTTAGAATTTCAGAAAAAAATGTTCCAGCAAAATTATTTGAGACTGAAGTGT
ACTTGTTAGATCTTACAGCAGTTGTTGCAGGGACTCAATTTCGAGGGCAATTTGAAAGTAGAATGAAGTCCATAATTGAT
GAAGCTAAATCAAATGGTAATGTTATATTGGTAATTGATGAGCTTCATAATATAATGGGTGCAGGAGAAGCACAAGGTGG
CTCTATGAATGCTGCAAACATTTTAAAACCTGCTCTTGCAAGAGGTGAGATACAAGTAATAGGAGCAACCACTTTAGATG
AGTATAGAAAATATATAGAAAAAGATTCTGCTCTAGAGAGAAGATTTCAACCTGTCTTAGTAGAAGAACCTACAGTTGAG
GAAACTATAGAAATATTAGAAGGCATAAAAGATTACTATGAACAATATCATCAAGTTAAAATATCTCATGAAGTAATTGA
AAACGCTGTAAATCTATCAGAAAGATATATAAATGATAGATTCTTACCTGACAAAGCTATAGATGTAATTGATGAAGCGA
GTTCCAGAGCTAACTTAAAAAATAAAGGATTAGTTGAATTAAAGTCACTAGAAGATGAACTTGAAAAAGTTCAAAATGAA
AAACAAAAGGCAGCTGATAGTGATGACTATGAAAAAGCAGCAGAATGTAAAGTAGAAGAATGCAGGTTAAAAGATAAAAT
AGATGAATTGAGAAAACAATGTACTGATGTAGAATTAACCACTGAAGATATTGCATTTGTAATAGAAGCTTGGACTAAAA
TACCAGTTCAAAGAATTACAGAAGAAGAAGGGGAAAAACTTATAAACCTAGAAGAAAGACTTCACAAAAGAGTTATAGGG
CAAAATGAAGCAGTAAAATCTTTAGGGAGGGCAATACGTCGTAATAGATTAGGATTTAGAAAAAAGAAAAAACCAGCTTC
ATTTATATTTGTTGGACCTACAGGAGTTGGAAAAACAGAACTTGTAAAAGCACTTGCAAGTGATTTATTTGAAAGTGAAG
ATGCTTTAATTAGAATAGATATGTCTGAGTACATGGAAAAGCACACTGTATCTAAGTTAATTGGAGCGCCTCCAGGATAT
GTAGGATATGATAATGGAGGACAATTAACAGAAAAAGTTAGAAGAAAGCCATATTCAGTAATACTTTTAGATGAAATAGA
AAAAGCTCATCCAGATGTATTTAATATGTTGCTTCAAATACTTGAAGATGGAAGACTTACAGATAGCCAAGGAAGAATGG
TTTCTTTTGAAAACACAGTAATTATAATGACATCAAATGTAGGTACTAACTTTAAAAGTGATAGCATAGGTTTTGGAAAA
GAAGGCTATGATGCTATGGAAATCCGTGTTAAAGAAGCTTTAAAAGAAACATTTAGACCGGAGTTTATAAATAGAATAGA
TGAAATAGTGGTATTTAACAATTTAAATAAAGAAGAATTATATAAAATCATTGATTTAATGATAGATGAAGTTAAAAATG
AGATTAAAGGAAAGAAATTAACATTAACTATTGATGATACAGTAAAAGATTATATCCTAAAAATAGGATATGATAAAAAA
TACGGTGCTAGACCTTTAAGAAGAGCTATACAAAGACATATTGAAGATGAAATAGCAGAAGCATATCTTCTTAAAAAGTT
TAAAGAAGGTTCTAACATAAATGCAAAAGTAGTTGATGATAAAATTGTTTTAGAATAG

Protein sequence :
MEMCSICKKNIATIYTAKIEDGKTKMVGICLECAKKMGMPIMDQFMKQAGITSEDMDNLTEQMNKVFEETNIDDLANNNF
LTNVLNGIFPKNDEEDYADNLDSLEFDKEKTSEKDKTNSEGIRTKNIFKNKKKTKYLNKYGINLTDKAKEHKVDKVVGRN
REIDRVIQILNRRNKNNPILIGEPGVGKTAIAEGLAVRISEKNVPAKLFETEVYLLDLTAVVAGTQFRGQFESRMKSIID
EAKSNGNVILVIDELHNIMGAGEAQGGSMNAANILKPALARGEIQVIGATTLDEYRKYIEKDSALERRFQPVLVEEPTVE
ETIEILEGIKDYYEQYHQVKISHEVIENAVNLSERYINDRFLPDKAIDVIDEASSRANLKNKGLVELKSLEDELEKVQNE
KQKAADSDDYEKAAECKVEECRLKDKIDELRKQCTDVELTTEDIAFVIEAWTKIPVQRITEEEGEKLINLEERLHKRVIG
QNEAVKSLGRAIRRNRLGFRKKKKPASFIFVGPTGVGKTELVKALASDLFESEDALIRIDMSEYMEKHTVSKLIGAPPGY
VGYDNGGQLTEKVRRKPYSVILLDEIEKAHPDVFNMLLQILEDGRLTDSQGRMVSFENTVIIMTSNVGTNFKSDSIGFGK
EGYDAMEIRVKEALKETFRPEFINRIDEIVVFNNLNKEELYKIIDLMIDEVKNEIKGKKLTLTIDDTVKDYILKIGYDKK
YGARPLRRAIQRHIEDEIAEAYLLKKFKEGSNINAKVVDDKIVLE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-151 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NT01CX_0220 YP_878724.1 negative regulator of genetic competence clpC/mecB VFG0079 Protein 1e-157 56
NT01CX_0220 YP_878724.1 negative regulator of genetic competence clpC/mecB VFG0080 Protein 2e-148 55