Gene Information

Name : NT01CX_2101 (NT01CX_2101)
Accession : YP_878174.1
Strain : Clostridium novyi NT
Genome accession: NC_008593
Putative virulence/resistance : Virulence
Product : tetanolysin O
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1296785 - 1298329 bp
Length : 1545 bp
Strand : +
Note : identified by match to protein family HMM PF01289

DNA sequence :
ATGAAGAAATCTTTAAAAACTATAATTCGTAGCATATCTTTTCTCTCAATATTAACATTAACTTGTAGTTGCAACTTTAT
AACAAGCACCCAGAAAAATGTAAGCTTATTATCGGGACCTAATAAAGTTATTAAACCTAAGAAAACTAAATCCTTAGATG
ATAGGATTTATGGATTAAAATATGATCCTAATAAAATACTATCATTTAATGGAGAAAAAGTTGAAAATTTTGTACCTAAC
GAAGGTTTTTCAACACCCGATAAGTACATCGTTATAAAACGTGAAAAGAAAAGTATATCAGATTCTACAGCAGATATAGC
TGTTATAGACTCGATGAATGACAAAACTTATCCTGGTGCAATACAACTTGCAAATAGAAATCTTATAGAAAACAAGCCTA
ATATAGTATCTTGTGAAAGAAAGCCAATAACAATAAGTATAGATTTACCTGGGATGGGTGAAGAAGGGAAGACAACTATA
ACTTCTCCTACTTATTCTTCTGTTAAAGCAGGAATTGATTCATTGCTAAATAAGTGGAATTCACATTATTCGTCAATATA
TAGCATTCCAACTAGATTTAGCTATTCAGATTCTATGGTTTATAGTAAGTCTCAATTATCAGCTAAATTAGGTTGTAATT
TCAAAGCTTTAAATAAAGCATTGGATATTGATTTTGATTCTATTTATAAAGGACAAAAGAAAGTAATGCTTCTTGCATAT
AAGCAAATTTTTTATACAGTAAATGTAGATGCCCCAAATCATCCATCAGACTTCTTTGGGGATAAAGTAACATTTAATGA
CTTAGCAAAAAAAGGAGTTAATAGTAAGAATCCTCCTGTATACGTTTCAAGTGTATCTTATGGTAGAACTATTTATGTAA
AACTTGAAACTACTTCTAAAAGTGCCAATGTAAAAGCTGCATTTAAAGCACTAATAGAAAATCAAAATATAAGCAGTAAT
TCTGAGTACAAAAATATTTTAAATCAAAGCTCATTTACAGCTACAGTATTAGGTGGTGGAGCTAAAGAACATAACAAAGT
AATAACTAAAAACTTTGATGAAATAAGAAATATAATAACTAACAACTCAGAATATAGTCCTAGAAATCCAGGTTATCCTA
TAGCATATACTACTTCTTTTCTAAAAGATAATAGTGTTGCAACAGTGAACAATAAAACAGATTATATAGAGACAACCTCT
ACAGAATATACTAATGGAAAAATTACTCTTGATCATAGAGGTGCATATGTAGCTAAATTCAATATTACTTGGGATGAAGT
AAGCTATGATAAGAATGGAAAAGAAATAGTAGAACACAAATCATGGGAAGGAAATGACTTCGGTAGAACAGCTCATTTCA
ATACAGAATTATACCTAAAAGGTAACGCTCGAAATATTTGCATAAAAGCTAAAGAATGCACTGGTCTTGCTTGGGAATGG
TGGAGAACTATAATAGATGATAAAAATGTTCCTTTAGTTAAAAACAGAAAAGTCTATATTTGGGGAACAACATTATATCC
TAGAACATTAACAGAAATAGAATAA

Protein sequence :
MKKSLKTIIRSISFLSILTLTCSCNFITSTQKNVSLLSGPNKVIKPKKTKSLDDRIYGLKYDPNKILSFNGEKVENFVPN
EGFSTPDKYIVIKREKKSISDSTADIAVIDSMNDKTYPGAIQLANRNLIENKPNIVSCERKPITISIDLPGMGEEGKTTI
TSPTYSSVKAGIDSLLNKWNSHYSSIYSIPTRFSYSDSMVYSKSQLSAKLGCNFKALNKALDIDFDSIYKGQKKVMLLAY
KQIFYTVNVDAPNHPSDFFGDKVTFNDLAKKGVNSKNPPVYVSSVSYGRTIYVKLETTSKSANVKAAFKALIENQNISSN
SEYKNILNQSSFTATVLGGGAKEHNKVITKNFDEIRNIITNNSEYSPRNPGYPIAYTTSFLKDNSVATVNNKTDYIETTS
TEYTNGKITLDHRGAYVAKFNITWDEVSYDKNGKEIVEHKSWEGNDFGRTAHFNTELYLKGNARNICIKAKECTGLAWEW
WRTIIDDKNVPLVKNRKVYIWGTTLYPRTLTEIE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
slo YP_281505.1 streptolysin O Virulence Not named Protein 1e-132 53
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 6e-120 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NT01CX_2101 YP_878174.1 tetanolysin O VFG2275 Protein 4e-141 59
NT01CX_2101 YP_878174.1 tetanolysin O VFG0976 Protein 3e-133 54
NT01CX_2101 YP_878174.1 tetanolysin O VFG0074 Protein 3e-120 48
NT01CX_2101 YP_878174.1 tetanolysin O VFG1363 Protein 4e-112 45