Gene Information

Name : NT01CX_1905 (NT01CX_1905)
Accession : YP_877978.1
Strain : Clostridium novyi NT
Genome accession: NC_008593
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 1113073 - 1114389 bp
Length : 1317 bp
Strand : +
Note : identified by match to protein family HMM PF00006; match to protein family HMM PF02874; match to protein family HMM TIGR01026

DNA sequence :
GTGGGGATAGAGATAAATTTTGAGAATATAAAAAATAAGATAGCCAAGTGTGACTTTAAGTATACAGAAGGATTAGTAAA
GCAAGTTATAGGTCTTACTATAGAAGTTGAAGGTATAAAGGCTTTCGTTGGAGAAGTTTGCACTATATACAATAAGGAAA
ACGAACCTATAATGTGTGAAGTAGTTGGTTTTAAAGAGGATAATGTAATATTAATGCCTCTTGGAGAACTTATTGGTATA
GGTCCTGGATGCAAGGTTGTTCCCTCTAAAAAATATCTAAGTGTTAAATGTTCAGATGATCTTTTAGGAAAGGTATTAAA
TGGACTTGGAAAACCACTAAAATCTGAGGAAGAACTTCCAATAGGAGTAGACTATCCACTAGATACTGCACCACCAGATC
CATTAAAAAGAAGAAGAATAAAAGATGAAATTGCAACTGGAGTTAGAGCAGTTGATGGATTTTTAACTTGTGGAGAAGGA
CAAAGAATAGGTATTTTTGCAGGTAGTGGAGTTGGAAAGAGTACAACACTTGGAATGATAGCAAGAGAAGCTAAAGCAGA
TATAAATGTAATTGCACTAATTGGTGAAAGAGGACGTGAAGTTCTAGATTTTATTGAAAAAGATTTAGGTGAGGAAGGCC
TTAAAAAATCAGTTATAGTTTGTGCAACATCAGATCAACCTGCACTTGTAAGATTAAAAGGAGCTTTTACAGCCACAGCT
ATAGCAGAATATTTTAGGGATAAAGGAAAAAAAGTAATTCTTATGATGGACTCTGTAACAAGATTTGCCATGGCTCAAAG
AGAAGTTGGACTAGCAATAGGAGAACCGCCAGCAACAAAAGGATACACTCCTTCAGTGTTTGCAATGCTTCCAAGACTTA
TGGAAAGATCAGGAATGTCAGATAAGGGTTCGATTACAGCTTTTTATACAGTATTAGTTGATGGTGATGACTTTAATGAA
CCAATTGCAGATGCTGTTCGTGGTATCCTTGATGGTCACATTGTATTATCAAGAGCACTAGCTGGTAAAAATCATTATCC
AGCAATAGATATTTTAAATAGTGTAAGCAGACTTATGAGCGAAATTGCAACAGATGAACATAAAAAAGCTGCATCACTTG
CAAGAGACTTACTTGCAACATATAAGAATTCTGAAGACCTTATAAATATAGGAGCATATGTTAGAGGAAGTAATCCTAAA
GTTGATATGGCAATACAATATAATGATGAATTAAATGATTATTTAAGACAGGGAATTAAAGAACATAGCGAATTTCAAGA
AAGTGTTACAAGACTTGTAAATATGTTTAATAATTAA

Protein sequence :
MGIEINFENIKNKIAKCDFKYTEGLVKQVIGLTIEVEGIKAFVGEVCTIYNKENEPIMCEVVGFKEDNVILMPLGELIGI
GPGCKVVPSKKYLSVKCSDDLLGKVLNGLGKPLKSEEELPIGVDYPLDTAPPDPLKRRRIKDEIATGVRAVDGFLTCGEG
QRIGIFAGSGVGKSTTLGMIAREAKADINVIALIGERGREVLDFIEKDLGEEGLKKSVIVCATSDQPALVRLKGAFTATA
IAEYFRDKGKKVILMMDSVTRFAMAQREVGLAIGEPPATKGYTPSVFAMLPRLMERSGMSDKGSITAFYTVLVDGDDFNE
PIADAVRGILDGHIVLSRALAGKNHYPAIDILNSVSRLMSEIATDEHKKAASLARDLLATYKNSEDLINIGAYVRGSNPK
VDMAIQYNDELNDYLRQGIKEHSEFQESVTRLVNMFNN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 5e-105 54
escN AAK26715.1 EscN Virulence LEE Protein 1e-86 51
escN YP_003223475.1 translocator EscN Virulence LEE Protein 6e-87 51
escN AAL57542.1 EscN Virulence LEE Protein 1e-86 51
escN NP_290268.1 hypothetical protein Virulence LEE Protein 6e-87 51
escN AAC38383.1 EscN Virulence LEE Protein 7e-87 51
ECs4568 NP_312595.1 EscN Virulence LEE Protein 6e-87 51
escN CAC81862.1 EscN protein Virulence LEE II Protein 6e-87 51
escN CAI43874.1 EscN protein Virulence LEE Protein 4e-87 51
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-85 51
escN AAC31513.1 L0034 Virulence LEE Protein 4e-87 51
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 4e-87 51
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-86 51
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 7e-87 51
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 3e-84 51
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 6e-102 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 8e-103 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 8e-103 50
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-100 50
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-101 50
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 8e-101 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-102 50
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-86 50
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-86 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-100 49
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-100 49
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-84 48
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 5e-85 48
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 9e-85 48
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 9e-85 48
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-85 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-75 45
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 9e-76 45
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-75 45
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-75 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 5e-77 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-77 45
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 6e-82 45
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 1e-71 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-79 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 3e-80 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-79 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 1e-85 44
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-69 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-71 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 6e-71 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-71 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-71 42
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-69 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NT01CX_1905 YP_877978.1 flagellum-specific ATP synthase VFG2144 Protein 4e-113 57
NT01CX_1905 YP_877978.1 flagellum-specific ATP synthase VFG0390 Protein 3e-101 52
NT01CX_1905 YP_877978.1 flagellum-specific ATP synthase VFG0192 Protein 9e-106 52
NT01CX_1905 YP_877978.1 flagellum-specific ATP synthase VFG0048 Protein 1e-103 52
NT01CX_1905 YP_877978.1 flagellum-specific ATP synthase VFG1254 Protein 1e-99 51
NT01CX_1905 YP_877978.1 flagellum-specific ATP synthase VFG0730 Protein 4e-87 51
NT01CX_1905 YP_877978.1 flagellum-specific ATP synthase VFG0812 Protein 2e-87 51
NT01CX_1905 YP_877978.1 flagellum-specific ATP synthase VFG2331 Protein 2e-86 48
NT01CX_1905 YP_877978.1 flagellum-specific ATP synthase VFG0515 Protein 3e-85 48
NT01CX_1905 YP_877978.1 flagellum-specific ATP synthase VFG2499 Protein 3e-89 47
NT01CX_1905 YP_877978.1 flagellum-specific ATP synthase VFG1778 Protein 7e-71 44
NT01CX_1905 YP_877978.1 flagellum-specific ATP synthase VFG2459 Protein 1e-72 42
NT01CX_1905 YP_877978.1 flagellum-specific ATP synthase VFG0555 Protein 3e-71 42
NT01CX_1905 YP_877978.1 flagellum-specific ATP synthase VFG1008 Protein 3e-66 41