Gene Information

Name : Acel_0690 (Acel_0690)
Accession : YP_872449.1
Strain : Acidothermus cellulolyticus 11B
Genome accession: NC_008578
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 750471 - 751916 bp
Length : 1446 bp
Strand : -
Note : TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: cjk:jk1442 putative mercuric reductase

DNA sequence : 
GTGTTGGTCCGCATATCCGAATATCTCGAGGAGCGTGCCGTGCATTACGACTTAGCAATCATCGGCTCGGGGAGTGCAGC
GTTCGCCGCCGCCATCACCGCGGTCGGCCGCGGCGCGACCGTCGTGATGGTGGAACGGGGACAGATCGGCGGGACCTGCG
TCAACGTCGGATGCGTCCCCTCGAAAGCCCTCCTCGCCGCCGCCGCTGCTCGGCATACCGCCAGCGATTCGCGCTTCCCG
GGTATTGCGACCACCGCTGGTCCGGTGGACGCCGGCGCCCTGAGGGCCGGCACGGATGCCCTCGTCCAGCAGTTGCGCGC
CGAGAAGTACGTCGACCTCGCGGCGGAGTATGGCTGGACGATCGTCCGGGGCACGGCACGTTTTGCACCGGGACCGGTCC
TTACCGTGGCGACCGAGGACGGTCCCGCGCAACTCGAGGCAGACCACTACCTGATCGCCACCGGCGCCTCCCCGTGGGCC
CCGCCGATCGAGGGCCTGGCGGAGTCCGGCTTCCTCACCTCGACGACGGCGATGGAGCTCACCGAGATACCCGACTCCCT
CCTCGTGGTCGGCGGCAACGCCGTCGGCTTGGAGATGGCCCAACTCTTTTCCCGGCTGGGCAGCACCGTCACCGTCGTCG
AAGCCCTTGACCGGATCGCCCCCTTCGAGGAACCGGAGATCAGTGCCGCGCTCCGCGACGTCTTTGCCGACGACGGCATC
ACCGTGCACACGTCGGCGCGGATCCGCCGAGTTCGCCGCGGGCCAGAGGGCTACCTCCTCGAGACCGACCTTCCCGAGGG
TCCGCGTACCCTGAGCGGCCGCGAGCTTCTCATCGCGACCGGCCGGCGGCCCAACACCGCCGATCTCGGTCTTGCAGCCG
TCGGCGTTGCTGCCGGCAGCCGCGGCGAAGTCGTCGTCGACGCCCAGCAGCGGACGACCAACCCGCGGATCTGGGCCGCC
GGCGACGTTACCGGCGGACCGCAGTTCGTCTACGTCGCCGCCGCGCAAGGAAATCTCGCCGCCCGCAACGCCCTCGACGG
CAGCGCAGAAAGCCTGGACTACTCCGCGCTGCCGCGCGTCACCTTCACCGAACCGTCGATCGCTTCGGCCGGCATGACCG
ACGCCCAGGCTGTCGCCGCCGGAATCCGCTGCGACTGCCGGGTCCTGCCGCTGGCGATGGTTCCCCGGGCCTTGGTCAAC
CGCGACACCCGGGGCCTGGTCAAGCTGGTCGCCGATGCGGACAACGGCCGGCTCGTCGGCGTCCACGTGCTGACCGACAA
CGCCGGAGACGTCATCGCCGGGGCGGTGTACGCGCTCACCGCGAAGATGACGGTCCAGCAGCTCGCCGACACCTGGTCGC
CGTACCTCACGATGGCCGAATCGCTCCGGCTCGCCGCCCAGGCCTACACCCGGGACGTCGCCAAACTGTCCTGCTGCGCC
GCGTAA

Protein sequence : 
MLVRISEYLEERAVHYDLAIIGSGSAAFAAAITAVGRGATVVMVERGQIGGTCVNVGCVPSKALLAAAAARHTASDSRFP
GIATTAGPVDAGALRAGTDALVQQLRAEKYVDLAAEYGWTIVRGTARFAPGPVLTVATEDGPAQLEADHYLIATGASPWA
PPIEGLAESGFLTSTTAMELTEIPDSLLVVGGNAVGLEMAQLFSRLGSTVTVVEALDRIAPFEEPEISAALRDVFADDGI
TVHTSARIRRVRRGPEGYLLETDLPEGPRTLSGRELLIATGRRPNTADLGLAAVGVAAGSRGEVVVDAQQRTTNPRIWAA
GDVTGGPQFVYVAAAQGNLAARNALDGSAESLDYSALPRVTFTEPSIASAGMTDAQAVAAGIRCDCRVLPLAMVPRALVN
RDTRGLVKLVADADNGRLVGVHVLTDNAGDVIAGAVYALTAKMTVQQLADTWSPYLTMAESLRLAAQAYTRDVAKLSCCA
A

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA ABQ57371.1 MerA Not tested SGI1 Protein 2e-72 47
merA AGK07021.1 MerA Not tested SGI1 Protein 2e-72 47
merA AGK07079.1 MerA Not tested SGI1 Protein 2e-72 47
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 8e-72 47
merA AFG30120.1 MerA Not tested PAGI-2 Protein 1e-70 46
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 2e-70 46
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 1e-70 46
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 3e-71 46
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 4e-71 46
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 6e-79 45
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 4e-79 45
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 3e-69 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Acel_0690 YP_872449.1 mercuric reductase BAC0652 Protein 2e-73 47
Acel_0690 YP_872449.1 mercuric reductase BAC0653 Protein 3e-71 47
Acel_0690 YP_872449.1 mercuric reductase BAC0651 Protein 3e-79 45
Acel_0690 YP_872449.1 mercuric reductase BAC0650 Protein 2e-67 44