Gene Information

Name : lysS (Acel_0216)
Accession : YP_871976.1
Strain : Acidothermus cellulolyticus 11B
Genome accession: NC_008578
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 230220 - 231725 bp
Length : 1506 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGACCAGTCACAGCCAACCACTCGAGCCGGACGATTTCGACGTCCCGGAGCAGTTTCGGGTCCGCCGGGAAAAGCTTGC
GCGGATCCGCGCGGAGGGCCTGGATCCGTATCCGGTCGGCTTTCCCCGGACCGCCTTTATTGCAGAGATTCGCGCGGCGT
ACGGCGATCTGCCGCCCGATACCTTCACCGGTCAACACGCCTCGATCGCCGGGCGGTTGATGCTGTCCCGGATCGGCGGC
AAACTCTGCTTCGGCGTGCTGCGGGATGGTTCCGGTGACCTGCAAATAATGCTCTCGGCACAGAAGGTGGGTGACCGCGC
GCTGGCGCTCTGGAAGAGCCTTGTCGATCTCGGCGATCACATCGGCGTGCACGGTGAGATCATCACCTCGCGGAGCGGCG
AGTTGTCGATTCTCGCCGACTCGTGGTCGTTCACGAGCAAGGCGCTCCGGCCGTTGCCGGAGAAGCACAAGGGTTTGACC
GATCCCGAGGCGCGGATTCGCCGTCGGTACGTCGATCTCATCGTGAATTCCCGGGCGCGGTCGATGGTCCACATCCGTGC
CGCCGTGTTGCGCTCCCTCCGGGACACTCTGAGCCGGCGCGGATACCTCGAGGTCGAGACCCCTGTCCTCCAGCTGGTGC
ACGGAGGCGCGGCTGCGCGGCCGTTCCGCACCCATCTCAATGCCTTCGACCTGCCCTTGTATCTGCGGATCGCCCTCGAG
CTGCCGCTCAAACGCCTGGTCGTCGGCGGCTTGGAACGCGTCTACGAAATCGGCCGGGTCTTTCGCAACGAAGGGGTCGA
TTCGTCGCACAGCCCGGAATTCACCGAACTGGAGGCGTACGAGGCCTACGGTGATTACGACACGATGGCTGACCTCGTTC
GTGAGCTCGTACTTGACGCGGCGAAGGCAATCGACGCGGTTCAGGTGCTGGGTTCATCCGGTGATGTCATCGATCTGGCC
GGTCCGTGGCGCACCGTCACGGTGCATCAGGCGGTCTCCGAGGCCGTCGGTGAAGAAATCACCGTCGACACCCCGGCTGC
GGTGCTCCATCAGATCGCGGCGCGATACAACGTACCGGTTCCTCCGGCGGCGGAGCATGGCGAGGTTGTCTGCGAGCTCT
TCGAGAAGGTCGCCCAGCCGGCGATCGTCCAGCCGACATTCGTTCGTGACTTTCCGGCTTCCGTTCGCCCATTGGCCCGG
CCGCATCGGACGGATCCTCGGCTGGCCGAAGCGTGGGATCTCATCATCAACGGCATAGAGCTGGCCCCGGCCTACTCCGA
GCTTGTCGATCCGGTCGAGCAGCGCCGGCGGTTGACCGAGCAGTCGGTCCGTGCCGCCGGTGGAGATCCGGAGGCAATGC
AATTGGACGAGGATTTCCTGCAGGCCCTGGAGTACGGCGCGCCGCCGATGGGCGGGTTGGGGCTTGGGGTGGACCGCCTG
CTGATGCTGCTCACCGGATCGGGTATCCGGGACGTCATCCTCTTCCCCCTCGTCCGGCCCGAATAG

Protein sequence :
MTSHSQPLEPDDFDVPEQFRVRREKLARIRAEGLDPYPVGFPRTAFIAEIRAAYGDLPPDTFTGQHASIAGRLMLSRIGG
KLCFGVLRDGSGDLQIMLSAQKVGDRALALWKSLVDLGDHIGVHGEIITSRSGELSILADSWSFTSKALRPLPEKHKGLT
DPEARIRRRYVDLIVNSRARSMVHIRAAVLRSLRDTLSRRGYLEVETPVLQLVHGGAAARPFRTHLNAFDLPLYLRIALE
LPLKRLVVGGLERVYEIGRVFRNEGVDSSHSPEFTELEAYEAYGDYDTMADLVRELVLDAAKAIDAVQVLGSSGDVIDLA
GPWRTVTVHQAVSEAVGEEITVDTPAAVLHQIAARYNVPVPPAAEHGEVVCELFEKVAQPAIVQPTFVRDFPASVRPLAR
PHRTDPRLAEAWDLIINGIELAPAYSELVDPVEQRRRLTEQSVRAAGGDPEAMQLDEDFLQALEYGAPPMGGLGLGVDRL
LMLLTGSGIRDVILFPLVRPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 6e-102 48