Gene Information

Name : cvrA; nhaP2; ycgO (Shewana3_0847)
Accession : YP_868491.1
Strain : Shewanella sp. ANA-3
Genome accession: NC_008577
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 983483 - 985207 bp
Length : 1725 bp
Strand : +
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
GTGGATGCAGATTCCATCAATAGTTTTTTTCTGATCGGTGCCTTGCTTGCCGCTGTGAGTGTTTTGTTAAGTCCCGTGTC
TTCGCGCTTGGGTATCCCTATCTTATTAATTTTCCTCGCTGTAGGGATTTTAGCTGGGGAGGATGGTCCCGGCGGTATTC
TGTTTGACGACTACTCAACCGCTTATCTTGTCAGTAACTTAGCCTTAGCCATTATCTTGCTCGATGGCGGTATGCGCACG
CGTGTCGCAAGCTTTAGGGTGGCACTGTGGCCAGCATTGTCGCTGGCGACCTTTGGGGTCGCTATCACCACCAGTATCAC
GGGCGTAATGGCCGCATGGTTATTTGACTTACACTGGTTGCAAGGCTTGCTGGTGGGGGCAATTGTCGGCTCCACCGATG
CGGCGGCGGTATTCTCGCTATTAAAGGGACGTAGTCTTAACGAGCGTGTTGGCGCGACGCTGGAAATCGAATCGGGCAGT
AACGACCCAATGGCGGTGTTTTTAACCGTAACCCTGATTGCCATCCTCGCTAATGTGGACGCCGAGTTATCCGTAAGCTT
TATGCTGATAAGCTTTATCAAGCAGTTTGGTTTGGGGATTTTCCTTGGTCTTGGCGGCGGTTGGCTGCTGTGGAAGTTGG
TGAATTTAAGCAAGCTTGCCGAAGGCTTGTATTCGATTTTAGTGCTCAGTGGCGGTCTGATGATTTATGCCGCCTCGAAC
AAACTCGGCGGTAGCGGCATCCTGTCGATTTATCTCGTCGGTCTCTTCCTCGGCAACAAGCCTACCCGCGGTCGCCATTC
CATCCTAAACGTATTGGATGGCATGACTTGGGTCAGCCAAATCGGTATGTTCCTCGTATTAGGGCTGCTGCTCACACCAT
CTGATTTGTTGGATATTTGGCTACCGGGCTTAGCGTTAGCCTTTGGGATGATCCTGTTTGCCAGACCGTTAGCTGTATGG
CTCAGCTTGCTGCCCTTTAAGAGCTTTAGCAGTCGTGACCGCTGGTTTATCTCTTGGGTCGGGCTTCGTGGCGCCGTGCC
GATTATTTTAGCGGTATTCCCTATGATGGCGGGATTACCAGGCGCTCAGTTGTACTTTAACTTGGCATTCTTCGTGGTGT
TAGTGTCACTGCTTGTGCAGGGGGCGTCACTCACCACGGCGGCGCGTTTAGCTAAGGTGGAGTTACCGCCTAAGCCGTTG
CCGATTTCACGTTCTGGGGTTGAAATATACCCGAGCAGTGAATGGGAAGTGTTTGTGTACCATCTGAGTGAAAACAAATG
GTGCATCGGCGAACCGCTTAAACGCCTCTCAATGCCAGATGGAACAAGGATTGCGGCGGTATTTCGCCATAATACGCTGT
TGCACCCATCGGGCAGTACCTGCCTCGAAGCGGGGGATATTTTGTGTGTGCTTGGGCAAGAGAAGAGCCTAGAAGCCTTA
AGTAACCTGTTTAGTCAGGCGCCCGAAACCAAGGAAGTGCCACGTTTCTTCGGTGACTTCTTTATCGATACCGAGGTTAA
GCTGCTGGATCTGGCGCCGATTTATGGGCTGGAGTTAGACGAAGCAACCGGCGACATGACGGTCGCAGATTTAGTAGCGG
CTGAATTAGGCTCGCATCCGGTACTTGGGGATCAGTTCCTATGGCAGTCGCTGCATTGGGTGGTTGCAGGGCTCAATGAA
GGCAAAGTCACCAATGTGGGTATTCGCTTACCGGCGGAGGCTTAA

Protein sequence :
MDADSINSFFLIGALLAAVSVLLSPVSSRLGIPILLIFLAVGILAGEDGPGGILFDDYSTAYLVSNLALAIILLDGGMRT
RVASFRVALWPALSLATFGVAITTSITGVMAAWLFDLHWLQGLLVGAIVGSTDAAAVFSLLKGRSLNERVGATLEIESGS
NDPMAVFLTVTLIAILANVDAELSVSFMLISFIKQFGLGIFLGLGGGWLLWKLVNLSKLAEGLYSILVLSGGLMIYAASN
KLGGSGILSIYLVGLFLGNKPTRGRHSILNVLDGMTWVSQIGMFLVLGLLLTPSDLLDIWLPGLALAFGMILFARPLAVW
LSLLPFKSFSSRDRWFISWVGLRGAVPIILAVFPMMAGLPGAQLYFNLAFFVVLVSLLVQGASLTTAARLAKVELPPKPL
PISRSGVEIYPSSEWEVFVYHLSENKWCIGEPLKRLSMPDGTRIAAVFRHNTLLHPSGSTCLEAGDILCVLGQEKSLEAL
SNLFSQAPETKEVPRFFGDFFIDTEVKLLDLAPIYGLELDEATGDMTVADLVAAELGSHPVLGDQFLWQSLHWVVAGLNE
GKVTNVGIRLPAEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 1e-116 59
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 1e-116 59