Gene Information

Name : murD (Shewana3_3745)
Accession : YP_871369.1
Strain : Shewanella sp. ANA-3
Genome accession: NC_008577
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 4501653 - 4502972 bp
Length : 1320 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGCAAAGTCAGTATTCACACATAGTGTTAGGTTTGGGTGCTACCGGGCTCTCGGTAGTGCGCTATTTGTGTGGAAAAGG
CATTACGCCCTTGGTGATGGATAGTCGTCGCCAACCTCCAGGTGCGGACACCCTTGCCAGCGCATTCCCTGAGGTGCAGC
TGATTGCCGGCGGATTCGATTGCCGTTACTTAGTGCAAGCGACGCAAATCATTATCAGCCCAGGTATTGCGATTGATACG
CCCGAGGTGCGCGCGGCTCTGGATATGGGGATTGAAGTCATTGGCGATGTGGAGCTATTTGCCCGTGAGATTGCCGACCG
TAAACCTTGTGTGATTGGGATTACTGGCTCAAACGGCAAGTCGACCGTCACCACCTTAGTGGGTGAAATGCTGCGTGAAG
CCGGCATGGCGGTGGCCGTGGGGGGCAACATTGGCATTCCGGCGCTCGATCTGCTGACGGAAAATGCCGATATTTTTGTG
CTTGAGCTGTCGAGCTTCCAACTCGAAACCACTCATAGCTTGAATTGCGTGGCGTCGACCTGTTTGAACGTGACCGAAGA
TCATATGGACAGATACAGCGATATGGATGCCTATCGCAAGGCCAAGCTGCGTCTGTACCATCAAAGCCGCTCCATCATCT
TTAACCGTGATGATGCGCTGACTATCCCTACTGAGCCGATGAACCAAAACAGCTTTGGTTTAGCGCCGCCAGAGGGTGAT
GAGTGGGGCATTTGTGATAGCAAGATTTACCACGGTCACAGTGAAATTATGCCGATCACCGAAGTATCGCTGATTGGTAG
TCATAACCATGCCAACTTACTCGCTGCTATGGCGCTGGTGTATGCCGTGGGCGTAGAGAAGCAAGTCATGGCTAAAGTGG
CTCGTACCTTTACTGGCCTTTCTCATCGCTGTGAAGTGGTCGGTGTGAAAGCGGGCGTGACCTATGTGAACGACTCTAAG
GCGACCAATGTTGGCGCCACCGTCGCGGCGCTCGATGGGTTAAGCGATCACTTAGGTGACATTATTTTGATTGCCGGTGG
TGATGGTAAGGGCGCGGATTTCAGCCCGCTAGTCGAGCCGTTAACGAAAGTGACACACCTCATCACCTTAGGTCGCGATG
GTAATAAGATAGCTGCATTGAAGGAAGGGGCCATCAAGGTGGACTCTATGGCTGCTGCAGTGGCTAAGGCCGCCGAGTTA
GCCACCTCGGGCGATATCGTACTCCTATCGCCAGCCTGTGCGAGCCTAGATATGTACAGCAATTTTATGGCTCGTGGGGA
TGATTTTAGAAGCCAAGTGGAGCAACTCGATGGCGAGTGA

Protein sequence :
MQSQYSHIVLGLGATGLSVVRYLCGKGITPLVMDSRRQPPGADTLASAFPEVQLIAGGFDCRYLVQATQIIISPGIAIDT
PEVRAALDMGIEVIGDVELFAREIADRKPCVIGITGSNGKSTVTTLVGEMLREAGMAVAVGGNIGIPALDLLTENADIFV
LELSSFQLETTHSLNCVASTCLNVTEDHMDRYSDMDAYRKAKLRLYHQSRSIIFNRDDALTIPTEPMNQNSFGLAPPEGD
EWGICDSKIYHGHSEIMPITEVSLIGSHNHANLLAAMALVYAVGVEKQVMAKVARTFTGLSHRCEVVGVKAGVTYVNDSK
ATNVGATVAALDGLSDHLGDIILIAGGDGKGADFSPLVEPLTKVTHLITLGRDGNKIAALKEGAIKVDSMAAAVAKAAEL
ATSGDIVLLSPACASLDMYSNFMARGDDFRSQVEQLDGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 8e-59 42
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 8e-59 42