Gene Information

Name : thyA (Shewana3_3039)
Accession : YP_870670.1
Strain : Shewanella sp. ANA-3
Genome accession: NC_008577
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 3643150 - 3643944 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCAACAGTATTTAGACTTGATGAAGCACATCTTAGCCGAAGGTGTGGATAAATCAGACCGCACAGGTACCGGCACTCG
CTCAGTGTTTGGTTATCAAATGCGTTTCGATTTGAGTAAGGGCTTTCCCTTAGTCACTACCAAGAAGTGCCATATGCGCT
CGATTATTCATGAGCTATTGTGGTTCCTGAAAGGCGATACCAACATTGCTTATCTGCGTGAGAATAAAGTCAGTATTTGG
GACGAATGGGCCGATGAAAACGGCGATTTAGGCCCTGTTTATGGTGCGCAGTGGCGCAGCTGGCCGACCCAAAGTGGCGA
TGCTATCGACCAAATCGCTCAGGTAATTGCACAAATCAAATCTCAACCTGATTCACGTCGTTTAATTGTTTCGGCGTGGA
ACGTGGGTGAACTGGATAAAATGGCGCTGGCACCTTGCCATGCCTTTTTCCAATTCTATGTTGCCGATGGCAAATTATCC
TGTCAGCTGTATCAGCGTAGCTGTGATGTGTTCTTAGGCTTACCTTTCAATATCGCCAGTTATGCGCTGCTGACCATGAT
GGTGGCACAGCAATGTGATTTAGCTTTGGGTGACTTTGTGTGGACGGGCGGCGATACCCATTTGTACTCCAACCATATGG
AACAAACGGCGTTGCAGTTAAGCCGTGAGCCAAGACAGTTACCCACCATGACAATCCTGCGTAAACCCGCTTCAATCTTT
GATTATCAATTCGAAGATTTCGAGCTAACTCACTACGATCCACACCCGCATATCAAAGCCCCTGTCGCCGTTTAA

Protein sequence :
MQQYLDLMKHILAEGVDKSDRTGTGTRSVFGYQMRFDLSKGFPLVTTKKCHMRSIIHELLWFLKGDTNIAYLRENKVSIW
DEWADENGDLGPVYGAQWRSWPTQSGDAIDQIAQVIAQIKSQPDSRRLIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
CQLYQRSCDVFLGLPFNIASYALLTMMVAQQCDLALGDFVWTGGDTHLYSNHMEQTALQLSREPRQLPTMTILRKPASIF
DYQFEDFELTHYDPHPHIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 1e-78 64