Gene Information

Name : guaA (Mmc1_3014)
Accession : YP_866911.1
Strain : Magnetococcus marinus MC-1
Genome accession: NC_008576
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3769216 - 3770817 bp
Length : 1602 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGTCACCCTTAGCCTTCACTCTGGATATTGCTATGTCAGACGCGCTGCATTCGGAAAAGATCCTTATTCTGGATTACGG
TTCTCAGTATACCCAGCTTATTGCGCGGCGGGTGCGGGAGACCCAGGTCTATTGTGAAATCCATGGTCATGAGATGGCAG
CGGAGGCCGTTAGAGCCTTTAATCCGCAGGGGGTTATCCTCTCTGGTGGGCATCAATCGGTCTATGATGTTGGTGCCGCT
GAGCTGAATGATGCGGTGATGGCTTTGGGTGTGCCGGTATTGGGCATTTGTTATGGCATGCAGTTGTTGGGGCGTCATTT
TGGCGGCACTGTGGCCCCCAGCGATAAGCGCGAGTATGGTCGTGCGGAAATTCAGGCGTGTGCGGGGCAGGTTGGAGCAT
TGTTTGAGGGGTTTGTTGAAGCCGGCGCCAAAAGCACCGTGTGGATGAGCCACGGCGACCATGTTGAGATGCTGCCCAAG
GGGTTTGTGACCACCGCATCGACCCTGAATGCCCCCCTTGCGGCCATGGCGAATGAGGCGACCCATATGTATGGGGTGCA
GTTTCATCCCGAGGTCAACCATACCGATAATGGTGAGCGTTTGATCCATAATTTTGTGCGCACCATTTGTGGGTGTCACG
GTTTGTGGACATCGGATGGGTTTATTGAGTATGAGGTGGAGCGGGTTCGGGCCTTGGTGGGGGATGACAAGGTTATTTTG
GGTCTATCGGGTGGGGTAGATAGCTCGGTGGTGGCGGCGCTGCTGCACCGGGCCATTGGCGAGCAGCTGACCTGTGTGTT
TGTGGATAATGGCCTGTTGCGCTTGAATGAGGGGGATCAGGTGATGGAGACCTTTGCCCAAAATATGGGGGTAAAGGTGA
TCCGTGTGGATGCTGAGGCGCGTTTTTTGGGCAAGTTGGCGGGGGTGTCTGATCCAGAGAAGAAGCGCAAGATCATTGGT
CACACTTTTATTGAGATCTTTGATGAGGAGGCGGGCAAGATCGAGAATGCCAAATGGCTGGCGCAGGGCACGATCTATCC
GGATGTGGTGGAGTCGGCGGGTACCAAAACCGGCAAGGCGACCAATATTAAGTCTCATCACAATGTAGGGGGCTTGCCGG
AGGATATGCAGCTCAAGCTGTTGGAGCCGCTGCGGGAGCTGTTTAAGGATGAGGTGCGTAAGGTTGGCTTGGAGTTGGGT
TTGCCGCATCGCATGGTGTTTCGTCATCCCTTTCCGGGTCCTGGTTTAGGGGTACGGATTTTGGGTGAGGTTAAAAAGGA
GTATGCGGATCTGTTACGCCGGGCGGATGCCATTTATATGGATGAGCTCTATGCATCGGGCCACTATGAGCGTATTTCTC
AGGCGTTTACAGTGTTTTTGCCGGTGAAGAGTGTTGGGGTGATGGGGGATGGTCGCACCTATGATTATGTGGTGGCTTTG
CGTGCGGTGGAGACCAAGGATTTTATGACCGCCACTTGGTACCCTATGCCCCATGATCTGCTGAGCCACATTGCCAACCG
CATCATCAACGAGATTGACGGCATTAACCGCGTCACCTACGACATTACCAGCAAGCCCCCCGGCACCATTGAGTGGGAGT
AG

Protein sequence :
MSPLAFTLDIAMSDALHSEKILILDYGSQYTQLIARRVRETQVYCEIHGHEMAAEAVRAFNPQGVILSGGHQSVYDVGAA
ELNDAVMALGVPVLGICYGMQLLGRHFGGTVAPSDKREYGRAEIQACAGQVGALFEGFVEAGAKSTVWMSHGDHVEMLPK
GFVTTASTLNAPLAAMANEATHMYGVQFHPEVNHTDNGERLIHNFVRTICGCHGLWTSDGFIEYEVERVRALVGDDKVIL
GLSGGVDSSVVAALLHRAIGEQLTCVFVDNGLLRLNEGDQVMETFAQNMGVKVIRVDAEARFLGKLAGVSDPEKKRKIIG
HTFIEIFDEEAGKIENAKWLAQGTIYPDVVESAGTKTGKATNIKSHHNVGGLPEDMQLKLLEPLRELFKDEVRKVGLELG
LPHRMVFRHPFPGPGLGVRILGEVKKEYADLLRRADAIYMDELYASGHYERISQAFTVFLPVKSVGVMGDGRTYDYVVAL
RAVETKDFMTATWYPMPHDLLSHIANRIINEIDGINRVTYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-136 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-136 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-136 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-118 51