Gene Information

Name : Shewana3_4311 (Shewana3_4311)
Accession : YP_863826.1
Strain :
Genome accession: NC_008573
Putative virulence/resistance : Resistance
Product : putative mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 200669 - 202324 bp
Length : 1656 bp
Strand : -
Note : TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; Heavy metal transport/detoxification protein; KEGG: tbd:Tbd_13

DNA sequence : 
ATGATCTTACTATCGATAGAAGGGATGACCTGTCCAAGTTGCGTCGCTCACGTTAAAGAAGCGCTCGATGCGATCGAAGG
CGTGAATAAGGTTGAAATATCTTATGAAAACGCCAGCGCAACGATCACCACAAACGGTGGGGTCAGCGTAACCGATCTCA
TTGGAGCGATTGAAGCCCTGGGTTATAACCCCTTAGCGGAAAACACAGCACCGAACGCCTACTGTGACAACGAAAATACC
AGCAACACAGAAAGCAACCGAACTCAACATGTGGCGATTATCGGTACGGGTTCCGGCGCTTTTGCCTGTGCTATCAAAGC
CGCTGAAGGTGGTGCCAAGGTCACTCTTATTGAGGGAGCCGATGTGATTGGCGGCTGTTGCGTGAATGTCGGCTGCGTAC
CCTCAAAAATTTTGATCCGCGCCGCTCAATTGGCACAGCAGCAACGCAATAATCCCTTTGCCGGACTGGAAAATCATGCG
CCCCAATTGAGTCGAGCCTTGTTGGCTCAGCAGCAGACCGCTCGAGTCGAAGAGCTGCGCGCTGCAAAGTATCAGAATAT
TCTAGAGACAAATCCTGCGCTTAGTTTACTTAAAGGTTGGGCGCAATTTAAAAATGCAAACACCCTGATAGTCAGAAAAA
ATGATGGCACTGAGCAGGAAATCTTTGCTGATAAAATCCTGATCGCCACTGGCTCCACGCCAACCATTCCTCCCATCGAG
GGGCTGGCCGAAACGCCTTACTGGACCTCTACCGAAGCGCTGTTTGCCGAGGAATTGCCGCAGCACCTGGTGGTGATTGG
TTCATCGGTCGTGGCGCTAGAAATTGCCCAGGCTTACCGACGATTGGGCAGTGAAGTCACCGTGTTGGCAAGACACTCAC
TACTTTACAGTGAAGACCCCATAATCGGTGAAAAACTGGCAGGCTGTTTTGAAAAAGAAGGCATTCGAGTTTTAAACAAC
ACGCAAGCCACCCAAGTGACCCACGATGGAAATCAATTCACCCTGAACACTAATGCAGGCGAGCTCAGTTGTGATCGTTT
GCTGGTAAGCACCGGGCGACACGCCAATACCAGCCAACTCAATCTGGACGCGGTGGGTGTCACCACCAACAAAAAGGGCG
AAATCGTTGTTAACGAACGCATGGAAACCAATGTTGCTGGTATTTACGCTGCCGGTGACTGCTCTAACATGCCGCAATTT
GTCTATGTCGCCGCGGCCGCCGGTAGCCGTGCTGGTATCAATATGACGGGCGGCGACGCCAAACTGGATCTGTCCACCAT
GCCCGCCGTGATCTTTACCGATCCACAGGTGGCTACCGTCGGACTGACCGAGGAACAAGCCAGGGCTCAGGATATTGAGA
CCGACAGCCGCGTACTGGGTATGGAAAATGTCCCACGTGCGTTAGCCAACTTTGAAACCGACGGTTTTATCAAACTGGTC
ACAGAGAAGGAAACGGGGTTGTTGCTAGGCGCGCAGATCCTGGCTCACGAAGGCGGCGAACTGATCCAGAGTGCGGCTTT
AGCCATCCGCAACCGTATGACGGTGACGGAATTAGCCGACCAGCTTTTCCCTTACCTCACCATGGTGGAAGGTTTGAAGC
TCTGCGCGCAAACCTTTAACAAGGATGTCAAAGAACTGTCCTGTTGTGCAGGATAA

Protein sequence : 
MILLSIEGMTCPSCVAHVKEALDAIEGVNKVEISYENASATITTNGGVSVTDLIGAIEALGYNPLAENTAPNAYCDNENT
SNTESNRTQHVAIIGTGSGAFACAIKAAEGGAKVTLIEGADVIGGCCVNVGCVPSKILIRAAQLAQQQRNNPFAGLENHA
PQLSRALLAQQQTARVEELRAAKYQNILETNPALSLLKGWAQFKNANTLIVRKNDGTEQEIFADKILIATGSTPTIPPIE
GLAETPYWTSTEALFAEELPQHLVVIGSSVVALEIAQAYRRLGSEVTVLARHSLLYSEDPIIGEKLAGCFEKEGIRVLNN
TQATQVTHDGNQFTLNTNAGELSCDRLLVSTGRHANTSQLNLDAVGVTTNKKGEIVVNERMETNVAGIYAAGDCSNMPQF
VYVAAAAGSRAGINMTGGDAKLDLSTMPAVIFTDPQVATVGLTEEQARAQDIETDSRVLGMENVPRALANFETDGFIKLV
TEKETGLLLGAQILAHEGGELIQSAALAIRNRMTVTELADQLFPYLTMVEGLKLCAQTFNKDVKELSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA ABQ57371.1 MerA Not tested SGI1 Protein 6e-134 58
merA AGK07021.1 MerA Not tested SGI1 Protein 6e-134 58
merA AGK07079.1 MerA Not tested SGI1 Protein 6e-134 58
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 1e-131 58
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 2e-131 57
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 2e-131 57
merA AFG30120.1 MerA Not tested PAGI-2 Protein 2e-131 57
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 9e-129 56
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 1e-131 56
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 2e-131 56

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Shewana3_4311 YP_863826.1 putative mercuric reductase BAC0652 Protein 8e-131 56
Shewana3_4311 YP_863826.1 putative mercuric reductase BAC0653 Protein 2e-131 56
Shewana3_4311 YP_863826.1 putative mercuric reductase BAC0650 Protein 2e-126 55