Gene Information

Name : leuS (GFO_3032)
Accession : YP_863043.1
Strain : Gramella forsetii KT0803
Genome accession: NC_008571
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 3191901 - 3194789 bp
Length : 2889 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGTTACCACTTTAATAAGATCGAAGAGAAATGGCAGAAATACTGGGCAGATAACCAGACATTCAAAGCCTCAAACGA
TTCTGAAAAACCGAAATATTATGTGTTGGACATGTTTCCTTATCCTTCGGGGGCGGGATTGCATGTGGGACATCCGCTGG
GGTATATTGCCAGTGATATCTATGCTCGTTTCAAAAGGCATAAAGGTTTTAATGTGTTGCACCCTCAGGGGTATGACAGT
TTCGGACTTCCGGCTGAGCAATACGCTATTCAAACCGGTCAGCATCCCGCGGTAACTACTGAAAATAATATTGCCCGTTA
TCGGGAGCAACTGGATAAGATTGGCTTTTCGTTCGATTGGAGCCGGGAAGTGAGAACCAGTGAACCCGATTATTATAAGT
GGACGCAGTGGATCTTTATTCAGCTTTTTGAAAGCTGGTATGATCAGGAAGCGGAGAAATCCCGTGCAATCACTGAGCTT
GAAGAGATTTTTACTTCGGAAGGGAACTCAAGAATAAATGCAGCTAGTGATGATGATGTCGAAAAATTTTCTGCAGATGA
CTGGAACGCTTGTTCTGAAGATGAAAAAGAGCAAATTCTTTTAAAATACCGACTTACCTATTTGGCGGAAGCTGAGGTGA
ACTGGTGCCCGCAACTTGGGACTGTACTCGCAAATGATGAGATCGTAAACGGAGTTTCAGAGCGCGGAGGATATCCGGTA
GTAAGAAAGAAAATGACCCAGTGGAGTATGAGGATTTCAGCATTTTCTGAAAGATTACTCCAGGATCTTAATAAAATTGA
CTGGACCGAAAGTTTAAAGGAAAGTCAGCGTAACTGGATCGGGAAATCGGTAGGAGCACACGTCGATTTCAAAATTGAAA
ATTCAAAATTCAAAATTGGTGTATTTACAACCAGACCCGATACCATTTTTGGAGTTAGTTTTATGACGCTTGCTCCGGAA
CATGAACTTGTTGAAAAGATTACTACGGAAGACAGAAAAGAAGAAGTTCAGGCCTATATCGAAGCTAGTGCGAAACGAAG
TGAGCGCGAGCGTATGGCCGATGTGAAGACCATTAGTGGTGCATTTACCGGCGCTTATGCTGAACATCCCTTTACCAAAA
AGCCGGTGCCGATCTGGATCGGTGATTATGTACTTGCAGGCTATGGAACCGGAGCGGTGATGGCCGTACCTTGCGGAGAT
CAGCGTGATCATGATTTCGCAAGACATTTTGACCTGCTAATTCCTAATATTTTCGAGAATGTAGATGTTTCTCAGGAAGC
TTATGCGGGAAAAGAAGGCACGGTAATCGCAAATTCAGATTTCCTTAGCGGACTAGAATATAAAGAGGCTTTAAATAAAG
TGATTCTGGAACTTGAGAAGACAGGTCAGGGTTACGGAAAAACGAATTACAGACTTAGAGACGCGGTGTTTAGTCGCCAG
AGATATTGGGGAGAGCCATTTCCGGTATATTATGTAAACGGTCTTCCAAAAATGATCGATGAAAAATACCTTCCACTAAA
GTTACCGGAAGTGGAAAAATACCTCCCAACTGAAACCGGTGAACCGCCTTTAGGAAATGCAACTGACTGGGCCTGGGATT
CCAAAAATAATAAAGTAGTTTCAAATAAGGTGCTGAAACAATCCCGAAAGCTTTCGGGACAGCATGACGAACCTAATTCG
AATGTCACCCCGAGCGCAGTCGAGGGGTCAGACGATAACGGAATTTATCCTTTAGAACTGAACACCATGCCCGGATGGGC
GGGAAGCAGCTGGTATCTATTCAGATATATGGGTGCCGGGAACCCTGACAGATTTGTTTCTGAAGAAGCACAGAAATACT
GGGAAAATGTAGATCTGTATATAGGAGGTAGCGAACACGCAACCGGTCATTTACTGTATTCAAGATTCTGGACCAAATTT
TTATATGACCGTGGCTGGTTAACAGTTGAGGAACCCTTTAAAAAACTGATTAACCAGGGAATGATCCTTGGAACCAGTGC
TTTTGTTTACAGACTGGAAGGAGAGAATGTATTTGTATCGAAAAATCAGATCAATGGAAATAATGTTCAGCCGATTCATG
CCGATGTTTCTTTGGTAAACTCTTCTGATGAACTGGATATCGAGGGCTTTAAAAAATGGCGTCCTGAATTTGCTGATGCA
AAATTTCTTACTGAAGATGGTAAATATATAGTTGGCAGGGAAGTGGAGAAAATGTCCAAATCCAAGTATAATGTTGTAAA
TCCGGATGAGATCTGTCAGGACTATGGCGCAGATACTTTAAGAATGTATGAGATGTTTCTGGGGCCATTAGAGCAGGCGA
AACCATGGAATACGGCAGGGATTACTGGAGTTCATAATTTTCTGAAAAAGCTTTGGAAACTTTATTATGACGGAGAGGAA
TTCTTTGTTTCAGATGAAAAAGCTTCCGCAGATTCATTAAAAACTTTTCATAAGACAATCAAGAAGGTGACTGAAGATAT
TGAAGAATTCAGTTTTAATACTTCGGTATCCACCTTTATGATCTGTGTTAATGAACTAACTGCGCAGAAGTGTAATAGTC
GTGAGATACTGGAGCCTTTAGCTGTTTTGATCGCGCCTTATGCGCCTCACATAGCTGAAGAACTTTGGGAAAAGCTAGGA
AATTCAGAATCGGTTACTACCGCTAAATATCCTGAATTTGAAGAGAAATATCTGGTAGAAAGTATGAAGAACTATCCGGT
TTCCTTCAACGGTAAGATGAGGTTTACGATGGAGCTTTCTTTGGATATGTCTAAAGAGGAAATTGAAAAAACAGTAATGG
CAGATGAGCGTACCCAAAAGCAGCTCGATGGGCGTACACCTAAGAAAGTGATCGTGGTGCCAGGAAAGATCGTGAATATA
GTAGGTTAA

Protein sequence :
MSYHFNKIEEKWQKYWADNQTFKASNDSEKPKYYVLDMFPYPSGAGLHVGHPLGYIASDIYARFKRHKGFNVLHPQGYDS
FGLPAEQYAIQTGQHPAVTTENNIARYREQLDKIGFSFDWSREVRTSEPDYYKWTQWIFIQLFESWYDQEAEKSRAITEL
EEIFTSEGNSRINAASDDDVEKFSADDWNACSEDEKEQILLKYRLTYLAEAEVNWCPQLGTVLANDEIVNGVSERGGYPV
VRKKMTQWSMRISAFSERLLQDLNKIDWTESLKESQRNWIGKSVGAHVDFKIENSKFKIGVFTTRPDTIFGVSFMTLAPE
HELVEKITTEDRKEEVQAYIEASAKRSERERMADVKTISGAFTGAYAEHPFTKKPVPIWIGDYVLAGYGTGAVMAVPCGD
QRDHDFARHFDLLIPNIFENVDVSQEAYAGKEGTVIANSDFLSGLEYKEALNKVILELEKTGQGYGKTNYRLRDAVFSRQ
RYWGEPFPVYYVNGLPKMIDEKYLPLKLPEVEKYLPTETGEPPLGNATDWAWDSKNNKVVSNKVLKQSRKLSGQHDEPNS
NVTPSAVEGSDDNGIYPLELNTMPGWAGSSWYLFRYMGAGNPDRFVSEEAQKYWENVDLYIGGSEHATGHLLYSRFWTKF
LYDRGWLTVEEPFKKLINQGMILGTSAFVYRLEGENVFVSKNQINGNNVQPIHADVSLVNSSDELDIEGFKKWRPEFADA
KFLTEDGKYIVGREVEKMSKSKYNVVNPDEICQDYGADTLRMYEMFLGPLEQAKPWNTAGITGVHNFLKKLWKLYYDGEE
FFVSDEKASADSLKTFHKTIKKVTEDIEEFSFNTSVSTFMICVNELTAQKCNSREILEPLAVLIAPYAPHIAEELWEKLG
NSESVTTAKYPEFEEKYLVESMKNYPVSFNGKMRFTMELSLDMSKEEIEKTVMADERTQKQLDGRTPKKVIVVPGKIVNI
VG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 6e-129 41