Gene Information

Name : lysS (GFO_2926)
Accession : YP_862940.1
Strain : Gramella forsetii KT0803
Genome accession: NC_008571
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 3061282 - 3062991 bp
Length : 1710 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGCATAAAAAAAATTATATGCAGCAGTTATCAGAACAGGAACAAATTAGACGAGATAAATTAACGGCTATAAGAAAAGC
CGGTATCAATCCATATCCTGCAGATCTTTTTCCAGTAGACCATACCACTACCGGTATCAAGGAAAATTTTGAAGAAGGTA
AGAACGTAGTAATCGCTGGCCGGCTCATGTCCAGAAGGATTCAGGGTAAGGCTTCTTTTGCCGAACTTCAGGATTCCAAA
GGAAGAATTCAAGTGTATTTTAACAGAGATGAGATCTGTACCGGAGAAGACAAGTCTAAGTATAACGACCTTTATAAAAA
ATTGCTGGATATAGGTGATTTTATTGGAATTGAAGGAGAGCTTTTTAAAACTCAGGTTGGAGAGATGACCGTGATGGTAA
AAGATTTCCACCTGTTAAGTAAGGCTTTAAGACCACTTCCACTTCCAAAAACTGATAAAGAAGGAAATACGCATGATGGA
TTTAATGATCCTGAACAAAGATACCGCCAGCGTTACGCTGATCTTGCGGTAAACCCAAAGGTGAAAGAGATTTTTGTGAA
GCGCACAAAGCTTTTTAATGCAATGCGAAATTTCTTTAATGAAAGAGAATATTTTGAAGTAGAAACACCAATTCTTCAGT
CTATCCCTGGTGGTGCCGCGGCAAGGCCTTTCGTTACTCATCACAATGCGCTGGATATTCCATTATACCTTAGAATTGCG
AACGAACTTTATTTAAAAAGATTGATCGTTGGTGGTTTTGATGGTGTTTATGAATTCTCTAAAAACTTCAGAAATGAAGG
AATGGACAGGACTCATAATCCTGAATTTACGGCCATGGAAATCTATGTAGCATATAAAGACTACAACTGGATGATGGAGT
TCACCGAGCAATTGCTGGAACATTGCGCAGAGGCTGTGAATGGAACTACCGATGCTACTTTTGGAGAACATAAGATAAAC
TTTAAAGCACCGTATAAGCGTCTTAGTATGACAGATGCTATTATAGAATACACAGGTTTTGATATCACCGGAAAGTCTGA
AAAAGAACTTTACGAGGCTGCAAAAGGTATGGATATCGAAGTTGATGATACCATGGGGAAAGGAAAGCTGATCGATGAGA
TCTTCGGCGAGAAGTGCGAAGGGAAATTTATCCAGCCAACTTTTATTACAGATTATCCTAAAGAAATGAGCCCGTTATGT
AAGGAACACAGAGATAACCCTGAACTTACCGAGCGTTTTGAATTGATGGTCTGCGGAAAAGAGATCGCTAATGCTTATTC
TGAGCTGAATGATCCTTTGGATCAAAGAGAACGTTTTGAAGAGCAGCTGAAACTTTCAGAAAAAGGCGATGATGAAGCAA
TGTTCATTGATAACGACTTTCTTCGATCATTGGAATATGGTATGCCGCCAACATCAGGCCTAGGAATTGGAATGGACAGA
TTGATCATGTTTTTAACGAACAAGCAGTCTATTCAGGAAGTTCTCTTTTTCCCCCAAATGAAACCGGAGAAGAAAGCAGT
TGAACTAAGCGAAGAAGAAAAAGAAGTTTTCAAATTACTTAAAAATGATAGCGTTCATGAACTTAATGACATTAAGGAGC
AGTCAGGTTTAAGCAATAAAAAATGGGATAAAGCAGTAAAAGGACTTAGAAAACATAAAATGATAGATGTTTTTAAAGAA
GGAGAAACATTGAATATGAAGATTTCATAA

Protein sequence :
MHKKNYMQQLSEQEQIRRDKLTAIRKAGINPYPADLFPVDHTTTGIKENFEEGKNVVIAGRLMSRRIQGKASFAELQDSK
GRIQVYFNRDEICTGEDKSKYNDLYKKLLDIGDFIGIEGELFKTQVGEMTVMVKDFHLLSKALRPLPLPKTDKEGNTHDG
FNDPEQRYRQRYADLAVNPKVKEIFVKRTKLFNAMRNFFNEREYFEVETPILQSIPGGAAARPFVTHHNALDIPLYLRIA
NELYLKRLIVGGFDGVYEFSKNFRNEGMDRTHNPEFTAMEIYVAYKDYNWMMEFTEQLLEHCAEAVNGTTDATFGEHKIN
FKAPYKRLSMTDAIIEYTGFDITGKSEKELYEAAKGMDIEVDDTMGKGKLIDEIFGEKCEGKFIQPTFITDYPKEMSPLC
KEHRDNPELTERFELMVCGKEIANAYSELNDPLDQRERFEEQLKLSEKGDDEAMFIDNDFLRSLEYGMPPTSGLGIGMDR
LIMFLTNKQSIQEVLFFPQMKPEKKAVELSEEEKEVFKLLKNDSVHELNDIKEQSGLSNKKWDKAVKGLRKHKMIDVFKE
GETLNMKIS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-104 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_862940.1 lysyl-tRNA synthetase VFG1668 Protein 8e-105 46