Gene Information

Name : thyA (GFO_0288)
Accession : YP_956876.1
Strain : Gramella forsetii KT0803
Genome accession: NC_008571
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 334583 - 335407 bp
Length : 825 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAGTATCATGATCTCTTAAAACACGTACTAGAGCAAGGAGCACAAAAAGGGGACCGTACCGGCACGGGAACTAA
AAGTGTATTTGGCTACCAGATGAGATTTGACCTTAGCGAAGGTTTCCCTATGGTAACTACAAAAAAATTACACCTTAAAT
CTATCATTTACGAATTATTATGGTTTCTTAAAGGTGATACCAATATTGAATATTTGAAGGAAAACGGTGTTCGTATTTGG
AATGAATGGGCAGATGACAATGGAGATCTTGGACCGGTATATGGCCACCAGTGGAGAAACTGGAATGGTGAAGAAATAGA
TCAGATTAAAGAAATTGTACACTCCTTGAAGCATAATCCCAATAGCCGAAGAATGCTGGTTTCAGCCTGGAATCCTTCGG
TGCTTCCAGATACAAGTGTTTCATTTTCGGAAAATGTTGCCAACGGAAAGGCCGCCCTTCCCCCCTGTCACGCGTTTTTT
CAGTTTTATGTAGCCGATGGAAAATTATCCTGCCAGCTTTACCAGAGAAGTGCCGATATATTTCTGGGAGTACCTTTTAA
CATTGCTTCATATGCCCTGCTCACCATGATGATGGCTCAAGTTTGCGGTTACGAAGCGGGTGATTTTATACATACTTTTG
GAGATGCCCATATTTACAGCAATCATATGGAACAGGTAGAATTACAATTAAGCAGGGAGCCAAGGCAACTACCAATCATG
AAGATTAACCCTGAAGTTAAAGATATTTTTGATTTTAAGTTTGAAGATTTTACATTAGAGGATTACGATCCGCACCCGGG
TATAAAAGCCAAGGTTGCGATTTAG

Protein sequence :
MKQYHDLLKHVLEQGAQKGDRTGTGTKSVFGYQMRFDLSEGFPMVTTKKLHLKSIIYELLWFLKGDTNIEYLKENGVRIW
NEWADDNGDLGPVYGHQWRNWNGEEIDQIKEIVHSLKHNPNSRRMLVSAWNPSVLPDTSVSFSENVANGKAALPPCHAFF
QFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTMMMAQVCGYEAGDFIHTFGDAHIYSNHMEQVELQLSREPRQLPIM
KINPEVKDIFDFKFEDFTLEDYDPHPGIKAKVAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 5e-77 61