Gene Information

Name : thyA (AHA_0675)
Accession : YP_855217.1
Strain : Aeromonas hydrophila ATCC 7966
Genome accession: NC_008570
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 722497 - 723291 bp
Length : 795 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCGAGCCTATCTCGACCTGATGCAGAAGATCCTCGATGAAGGGACCGTCAAATCCGACCGTACCGGTACCGGCACCAT
CTCCCTGTTCGGCCATCAGATGCGCTTCAATCTGGCGGAAGGCTTCCCGCTGGTCACCACCAAGAAGTGCCACCTGCGCT
CCATCATTCACGAGCTGCTGTGGTTCCTCAATGGCGATACCAACACCGCCTACCTAAAAGAGCACGGCGTCAGCATCTGG
GATGAGTGGGCCGACGAGAACGGCGATCTGGGGCCGGTGTATGGTGCCCAGTGGCGCTCCTGGCCGGCGGCTGACGGGTC
TGTCATCGATCAGATCCAGAAGGCAGTGGACGACATCAAGCACAATCCGGATTCGCGCCGCATCATCGTCTCCGCCTGGA
ACGTGGGCGAGCTGGACAAGATGGCGCTGGCTCCCTGCCACGCCTTCTTCCAGTTCTACGTGGCCGACGGCAAGCTCTCC
TGCCAGCTCTACCAGCGCAGCTGTGACGTGTTCCTCGGCCTGCCGTTCAACATCGCCAGCTACGCACTGCTGACCCACAT
GATGGCCCAGCAGTGTGACCTGGAAGTGGGCGACTTCGTCTGGACCGGTGGTGATGTGCACCTCTACTCCAACCACATGG
AGCAGACCGCGCTGCAGCTCACCCGCGAGCCGCGCCCGCTGCCGACTCTGGTGATCAAACGCAAGCCGGACTCCATCTTC
GATTACAAGTTCGAGGATTTCGAAATAGAGGGTTACGACCCCCATCCCGGCATCAAGGCGCCCGTCGCCATCTGA

Protein sequence :
MRAYLDLMQKILDEGTVKSDRTGTGTISLFGHQMRFNLAEGFPLVTTKKCHLRSIIHELLWFLNGDTNTAYLKEHGVSIW
DEWADENGDLGPVYGAQWRSWPAADGSVIDQIQKAVDDIKHNPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
CQLYQRSCDVFLGLPFNIASYALLTHMMAQQCDLEVGDFVWTGGDVHLYSNHMEQTALQLTREPRPLPTLVIKRKPDSIF
DYKFEDFEIEGYDPHPGIKAPVAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 6e-88 67