Gene Information

Name : clpB (AHA_4071)
Accession : YP_858496.1
Strain : Aeromonas hydrophila ATCC 7966
Genome accession: NC_008570
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone protein ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 4505107 - 4507680 bp
Length : 2574 bp
Strand : -
Note : identified by similarity to SP:P63284; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
ATGCGCCTCGATCGCCTGACCAGCAAATTCCAGATTGCTATTTCCGATGCCCAGTCTTTGGCACTGGGTCGTGACCACCA
ATTCATCGAACCCGTTCACCTGATGACCGCCCTGGTCAATCAGGATGGCGGCTCCATCCGTCCGCTGCTCACCCTGACCG
GGATGGACATCAATTCTCTGCGCTCGCGCCTCGGCGAAGAGCTGGATCGGCTGCCCAAGGTGAGCGGCGTGGAGGGCGAT
GTGCAGCTCTCCAACGGCCTCGGCCGGCTGCTCAACGTCTGCGACAAGCTGGCTCAGCAGCGCAAGGATCAGTTCATCTC
ATCCGAACTGTTCGTGCTGGCGGCCCTCGACGAGAAGGGGACGCTGGGTGAGCTGCTGCGTGCCCAGGGGCTGACCAAGG
AGAAACTCGAAGCGGCCATCGACAAGGTGCGTGGCGGCAAGAAGGTGGAAGATGCCAACGCCGAGGAGAATCGCCAGGCG
CTGGAGAAATACACCATCGATCTGACCGAGCGGGCCGAGATCGGCAAGCTCGACCCGGTGATCGGCCGGGATGACGAGAT
CCGCCGCACCATCCAGGTGCTGCAACGCCGTACCAAGAACAACCCTGTGCTGATCGGTGCCCCCGGCGTCGGCAAGACCG
CCATCGTCGAAGGGCTGGCCCAGCGCATCATCAATGGCGAGGTGCCGGAGGGGCTCAAGAACAAGCGGGTGCTGTCGCTC
GACATGGGGGCGCTGGTGGCCGGTGCCAAGTATCGTGGCGAGTTCGAAGAGCGGCTCAAGGCCGTGCTCAACGATCTGGC
CAAGGAGGAGGGCAACGTCATCCTCTTCATCGATGAGCTGCACACCATGGTCGGCGCCGGCAAGGGTGAAGGCGCCATGG
ATGCGGGCAACATGCTCAAACCGGCGCTGGCCCGTGGCGACCTGCACTGCGTCGGCGCCACCACCCTGGACGAGTACCGC
CAGTACATCGAGAAGGATGCAGCCCTCGAGCGCCGCTTCCAGAAGGTGCTGGTGGAGGAGCCGAGCGTGGAGGACACCAT
CGCCATCCTGCGCGGCCTGAAGGAGCGTTACGAACTGCACCACCACGTGCAGATCACCGACCCTGCCATCGTGGCGGCGG
CCCAGCTGTCGCACCGCTACATCGCGGATCGCCAGCTGCCGGACAAGGCCATCGACCTCATCGACGAGGCGGCGGCCAGT
ATCCGGCTGCAGATCGACTCCAAGCCCGAGTCCCTCGATCGGCTCGAGCGGCGCATCATCCAGCTCAAGCTGGAGCAGCA
GGCACTGATGAAAGAGGACGATGACGCCAGCCGCAAACGGCTCGAGCTGATCAATCAGGAAATCAGCGAAAAAGATCGGG
AATACAACGAGCTGGATGAGGTGTGGAAGGCCGAGAAGGCCGCCCTCGCCGGCACCCAGCACATCAAGGCGGCCCTCGAG
CAGGCCCGCCAGGATCTCGACGTGGCGCGCCGCGCAGGCGATCTGGGCCGGATGTCAGAGCTGCAGTACGGCCGCATTCC
GGAACTGGAGAAACAGCTGGATCTCGCCACCCAGGCCGAGATGCAGGAGACCAGTCTGCTGCGCAACCGGGTCACCGACG
TGGAGATAGCCGACGTCCTGGCCCGCTGGACCGGTATTCCGGTGGCCCGCATGCTGGAAGGGGAACGCGACAAGCTGCTG
CGGATGGAAGATCAGCTGCACAGCCGGGTGATCGGCCAGGAAGAGGCGGTCGAGGCGGTTTCCAACGCCATTCGCCGCTC
CCGCGCCGGGCTGTCCGACCCGAACCGCCCCATCGGCTCCTTCCTGTTCCTGGGGCCCACCGGGGTGGGCAAGACCGAGC
TGTGCAAGGCGCTGGCCGAGTTCCTGTTCGATACCCAGGACGCCATGGTGCGGATCGACATGTCGGAGTTCATGGAGAAA
CACAGCGTGGCCCGTCTGGTGGGGGCGCCTCCGGGATACGTGGGTTACGAGGAGGGTGGTTATCTGACCGAGGCGGTGCG
CCGTCGCCCCTACTCGGTGATCCTGCTGGATGAAGTGGAGAAGGCACACCCGGACGTGTTCAACATCCTGCTGCAGGTGC
TGGACGATGGCCGCCTGACCGATGGTCAGGGTCGTACCGTCGATTTTCGCAACTCGGTGGTGATCATGACCTCCAACCTC
GGGTCGGATCTCATTCAGGAGCACCACTCCGAGAAGGATTACGACGAGATGAAGGGCATGCTGATGGAGGTGCTGACCCG
CAGCTTCCGGCCGGAGTTCATCAACCGGATCGACGAGACCGTGGTGTTCCACCCGCTCGGCGAGGAGCACATCAAGTCCA
TCGCCCGCATCCAGCTCAAGAGCTTGATGGGCCGACTGGAGGCTCAGGGTTACGAGGTGGAGGTGAGCGAGGCGCTGCTC
GAGAAACTGGTGCACGCCGGGTTCGATCCCGTCTACGGGGCGCGTCCCCTCAAGCGGGCGATCCAGCACAAGGTGGAGAA
CCCGCTGGCGCAGGCGCTGCTCTCCGGCCGCATCGTGCCGGGCAAAAAGCTGGTGCTGGGGGCCGACAGCAACGGCCTCA
CCATGACCCAGTAA

Protein sequence :
MRLDRLTSKFQIAISDAQSLALGRDHQFIEPVHLMTALVNQDGGSIRPLLTLTGMDINSLRSRLGEELDRLPKVSGVEGD
VQLSNGLGRLLNVCDKLAQQRKDQFISSELFVLAALDEKGTLGELLRAQGLTKEKLEAAIDKVRGGKKVEDANAEENRQA
LEKYTIDLTERAEIGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGAPGVGKTAIVEGLAQRIINGEVPEGLKNKRVLSL
DMGALVAGAKYRGEFEERLKAVLNDLAKEEGNVILFIDELHTMVGAGKGEGAMDAGNMLKPALARGDLHCVGATTLDEYR
QYIEKDAALERRFQKVLVEEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAAQLSHRYIADRQLPDKAIDLIDEAAAS
IRLQIDSKPESLDRLERRIIQLKLEQQALMKEDDDASRKRLELINQEISEKDREYNELDEVWKAEKAALAGTQHIKAALE
QARQDLDVARRAGDLGRMSELQYGRIPELEKQLDLATQAEMQETSLLRNRVTDVEIADVLARWTGIPVARMLEGERDKLL
RMEDQLHSRVIGQEEAVEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALAEFLFDTQDAMVRIDMSEFMEK
HSVARLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNSVVIMTSNL
GSDLIQEHHSEKDYDEMKGMLMEVLTRSFRPEFINRIDETVVFHPLGEEHIKSIARIQLKSLMGRLEAQGYEVEVSEALL
EKLVHAGFDPVYGARPLKRAIQHKVENPLAQALLSGRIVPGKKLVLGADSNGLTMTQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-156 44
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 7e-107 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_858496.1 ATP-dependent chaperone protein ClpB VFG0079 Protein 1e-142 44