Gene Information

Name : lysS (AHA_3369)
Accession : YP_857858.1
Strain : Aeromonas hydrophila ATCC 7966
Genome accession: NC_008570
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 3795335 - 3796870 bp
Length : 1536 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCTGAACAAACCACTACTCCGGAAGTCGACCAAACTCTCGATCTGAACAACGAGATGCAGGAGCGTCGTTCCAAGCT
GGCCGCCTTGCGCGCCCAGGGCAACCCCTTCCCCAACGACTTCCGTCGTGACAGCCTTTCCGGCGATCTGCACGCCGAGT
TTGGTGACAAGAGCGCCGACGAACTGGCCGCACTGGGTAAACGGGTGAAGATTGCCGGTCGCATCATGACCCGCCGGATC
ATGGGCAAGGCATCTTTCGCCACCCTGCAGGACATGGCTGGCAAGATCCAGGTCTACGTCACCCGTGACGACCTGCCGGA
AGGCTTCTACAACGAGCAGTTCAAGAAGTGGGATCTGGGCGACATCGTGGGTGTCGAAGGTACCCTGTTCCGCACCAACA
CAGGCGAACTCTCCGTTCATGTCTCCGACATTCGCCTGCTGACCAAGGCCCTGCGCCCGCTGCCCGAGAAGCACAAAGGT
CTGACCGACCAGGAAGCCCGCTGCCGTCAGCGTTACCTGGATCTGATCGCCAACGAAGAGTCCCGCAAGACTTTCGTGAC
CCGTACCAAGGTCGTGGCCGGTATCCGCAAGTTCCTGAACGACAAGCGCTTCATGGAAGTGGAAACCCCCATGATGCAGG
TCATCCCGGGTGGCGCCTCTGCCCGTCCGTTCATCACTCACCACAATGCGCTGGACATCGACATGTACCTGCGTATCGCT
CCGGAACTCTATCTGAAGCGTCTGGTGGTCGGTGGTTTCGAGCGTGTGTACGAGATCAACCGCAACTTCCGTAACGAAGG
TATCTCCGTTCGCCATAACCCCGAGTTCACCATGCTCGAGTTCTATATGGCTTACGCCGACTACATCGATCTGATGGATC
TCACCGAAGAGATGCTGCGCACCCTGGCGCAGGATATCCTGGGCGACACCAAGATCCGTTACGCCAAAGAGGGCGAAGAG
GGTCTGACCATCGATTTCGGTCAGCCGTTCCAGCGCCTCTCCATGGTTGACTCCATCCTGAAGTACAACCCGGATGTGAC
CCGTGACGATCTGGCGACCCTGGAGAAGGCCACCGCCGTCGCCAAGCGCCTGCACATCGAGCTGATGAAGAGCTGGGAAC
TGGGCCACGTGATCACCGCGATCTTCGAAGAGACCGTGGAGCACATGCTGCTGCAACCGACCTTCATTACCGAGTACCCG
GCCGCCGTTTCTCCGCTGGCCCGTCGCAACGACCAGAACCCGGACGTCACCGACCGCTTCGAATTCTTCATCGGCGGCCG
CGAGCTGGCCAACGGCTTCTCCGAGCTGAACGATGCGGAAGATCAGGCCGAGCGCTTCCAGGCTCAGGTTGACCAGAAAG
CCGCAGGCGATGACGAAGCCATGTTCTACGACGCCGACTTCGTGACCGCACTGGAACACGGTCTGCCACCGACTGCCGGT
CAGGGTATCGGTATCGACCGTCTGGTGATGCTGTTCACCAACAGCCACACCATCCGCGACGTCATCCTGTTCCCGGCTCT
GCGTCCACAAAAGTAA

Protein sequence :
MSEQTTTPEVDQTLDLNNEMQERRSKLAALRAQGNPFPNDFRRDSLSGDLHAEFGDKSADELAALGKRVKIAGRIMTRRI
MGKASFATLQDMAGKIQVYVTRDDLPEGFYNEQFKKWDLGDIVGVEGTLFRTNTGELSVHVSDIRLLTKALRPLPEKHKG
LTDQEARCRQRYLDLIANEESRKTFVTRTKVVAGIRKFLNDKRFMEVETPMMQVIPGGASARPFITHHNALDIDMYLRIA
PELYLKRLVVGGFERVYEINRNFRNEGISVRHNPEFTMLEFYMAYADYIDLMDLTEEMLRTLAQDILGDTKIRYAKEGEE
GLTIDFGQPFQRLSMVDSILKYNPDVTRDDLATLEKATAVAKRLHIELMKSWELGHVITAIFEETVEHMLLQPTFITEYP
AAVSPLARRNDQNPDVTDRFEFFIGGRELANGFSELNDAEDQAERFQAQVDQKAAGDDEAMFYDADFVTALEHGLPPTAG
QGIGIDRLVMLFTNSHTIRDVILFPALRPQK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 4e-148 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_857858.1 lysyl-tRNA synthetase VFG1668 Protein 2e-148 60