Gene Information

Name : leuS (AHA_3247)
Accession : YP_857738.1
Strain : Aeromonas hydrophila ATCC 7966
Genome accession: NC_008570
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 3662709 - 3665441 bp
Length : 2733 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
TTGTCCATGGCCGTTACTCCTCTACTGAACCCTGATCAGGCCCGGCTTAAGGCCCGAGGGACGCTGGCGGTTGTTGCCGC
CGCAGGATATGGGTATTCTATTGCGATTTCCCAGCTGATTTATCTATCCATTTCACAGATCCGGATGTCACCAATGCAAG
AGCAATACGTTCCCCAATCCATAGAACCAGCAGTGCAAAAGCACTGGGATGCCAAGAAAACCTTCAAGGCGGTGGAGAAA
GTAGACAAGGAAAAGTTCTACTGCCTCTCCATGTTCCCCTATCCGTCTGGTCGTCTACACATGGGGCACGTTCGCAACTA
CACCATAGGTGATGTGATCTCCCGTTATCAACGCCTCAATGGCAAGAACGTGCTGCAACCCATCGGTTGGGACGCATTCG
GCCTGCCGGCGGAAAACGCCGCCATCAAGAACAACACGGCACCGGCGCCCTGGACCTACGAAAACATCGAATACATGAAG
AACCAGCTGAAGATGCTGGGTCTAGGTTATGACTGGGATCGCGAGCTGGCCACCTGCAAGCCGGACTACTACCGCTGGGA
GCAGTGGTTCTTCACCAAGCTCTACGAGAAGGGTCTGGTCTACAAGAAGACCTCCTCCGTCAACTGGTGCCCGAACGACA
TGACCGTACTGGCCAACGAGCAGGTGGTGGACAACTGCTGCTGGCGCTGTGACACCCCGGTGGAGCAGAAAGAGATCCCC
CAGTGGTTCATCAAGATCACCGATTATGCCGAAGAGCTGCTGAACGATATCGACAATCTGGAAGGCTGGCCTGAGATGGT
CAAGACCATGCAGCGCAACTGGATTGGCCGCTCCGAAGGGGTCAACATCAGCTTCGCCATCGAGGGTCAGACTGAGCATC
TGGAGGTCTACACCACCCGTCCGGACACCTTCATGGGCGTGACCTATGTCGGTATCGCCGCCGGCCACCCGCTGGCGCTG
CAGGCAGCCGAGAGTAACCCCGAGCTCGCCGCCTTTATCGAAGAGTGCAAGAACACCAAGGTGGCCGAAGCCGAGCTCGC
CACCATGGAGAAGAAGGGCATGGCCACCGGCCTCTACGCCATTCACCCGCTGGATGGCCGCAAGGTGCCGGTCTGGGTCG
CCAACTTCGTGCTGATGAACTACGGCACCGGCGCCGTGATGGCGGTACCGGGCCACGACCTGCGTGACCATGAGTTCGCC
ACCAAGTACGGTCTCGAGATCAAGCCGGTCATCAAGCCGGTCGATGGCGAGCTGCCGAACGTGATCGACGCCGCCTACAC
CGACAAGGGCGTGCTGTTCAACTCAGGCGAGTTCGACGGCCTCGAGTTCCAGCCGGCATTCGATGCCATCGCCAGCAAGC
TGGAGAGCCTTGGCTGCGGCAAGCGCACCGTCAACTTCCGTCTGCGCGACTGGGGTGTCTCCCGTCAGCGCTACTGGGGT
GCCCCCATCCCCATGCTGACCCTGGCCGACGGCACAGTCGTGCCGACCCCGGAAGATCAACTGCCGGTGCTGCTGCCGGA
AGACGTGGTGATGGACGGTATCCAGAGCCCGATCAAGGCCGACGCCGAGTGGGCCAAGACCACCTACAACGGACAGGAAG
CGTTCCGCGAGACCGATACCTTCGACACCTTCATGGAGTCCTCCTGGTACTACGCCCGCTACTGCTCCCCGGACTACGAC
AAGGGCATGCTGGATCCGGCGGCGGCCAATCACTGGCTGCCGGTGGATCAGTACATCGGCGGCATCGAGCACGCCTGTAT
GCACCTGCTCTACGCCCGCTTCTTCCACAAGCTGCTGCGTGACGCTGGCCTCGTGAACAGCGACGAGCCGTTCAAGCGCC
TGCTCTGCCAGGGCATGGTGCTGGCCGACGCCTTCTACTACAAAGACGAGAAGGGCGGCAACGTCTGGGTCAGCCCGACC
GACGTCAAGGTGGAGCGTGACGAGAAAGGCCGCATCACCAAGGCCGTCGACAATGAAGGCCGTGAAGTGATCCACTCCGG
CATGACCAAGATGTCCAAGTCCAAGAACAACGGCATCGACCCGCAGCTGATGGTGGAGCGTTACGGCGCCGATACCGTGC
GTCTGTTCATGATGTTCGCCTCGCCGGCCGAGATGACCCTGGAGTGGTCCGACTCCGGCGTCGAGGGTGCCCAGCGCTTC
CTGCGTCGCCTGTGGCGCATCACCTTCGAGCACGTCAGTGCCGGCGTAGCTCCCGCACTGAATGTGGCGGCACTGAGTGT
CGACCAGAAGGCCGTGCGCCGCGAGCTGCACAAGACCATCGCCAAGGTGAGCGACGACGTGGGTCGCCGTCAGACCTTCA
ACACCGCCATCGCCGCCATCATGGAGCTGATGAACAACCTGGCCAAGCTGGGCAGCGACGAGCAGGATCGCGCCCTGATG
CAGGAAGCGCTGGAAGCGGTCGTGGTCATGCTCTACCCCATCACCCCGCACATCGGCTTCGAGCTGTGGAAGATGCTGGG
CAAGGGCGACGACGTGGATCACGCCACTTGGCCGGTGGCCGACGAAGCGGCCATGGTCGAGACTGAGAAGCTGGTGGTGG
TGCAGATCAACGGCAAGATGCGCGGCAAGCTGACCGTGCCGGCCGAGATCAGCCAGGCCGACGTCGAGAAGCTGGCCATG
GCCGATGCTTCGGTCCAGAAGTTCACCGACGGCCTGACCGTGCGCAAGGTGATCTACGTGCCGGGCAAACTGCTCAACAT
CGTGGCCAACTGA

Protein sequence :
MSMAVTPLLNPDQARLKARGTLAVVAAAGYGYSIAISQLIYLSISQIRMSPMQEQYVPQSIEPAVQKHWDAKKTFKAVEK
VDKEKFYCLSMFPYPSGRLHMGHVRNYTIGDVISRYQRLNGKNVLQPIGWDAFGLPAENAAIKNNTAPAPWTYENIEYMK
NQLKMLGLGYDWDRELATCKPDYYRWEQWFFTKLYEKGLVYKKTSSVNWCPNDMTVLANEQVVDNCCWRCDTPVEQKEIP
QWFIKITDYAEELLNDIDNLEGWPEMVKTMQRNWIGRSEGVNISFAIEGQTEHLEVYTTRPDTFMGVTYVGIAAGHPLAL
QAAESNPELAAFIEECKNTKVAEAELATMEKKGMATGLYAIHPLDGRKVPVWVANFVLMNYGTGAVMAVPGHDLRDHEFA
TKYGLEIKPVIKPVDGELPNVIDAAYTDKGVLFNSGEFDGLEFQPAFDAIASKLESLGCGKRTVNFRLRDWGVSRQRYWG
APIPMLTLADGTVVPTPEDQLPVLLPEDVVMDGIQSPIKADAEWAKTTYNGQEAFRETDTFDTFMESSWYYARYCSPDYD
KGMLDPAAANHWLPVDQYIGGIEHACMHLLYARFFHKLLRDAGLVNSDEPFKRLLCQGMVLADAFYYKDEKGGNVWVSPT
DVKVERDEKGRITKAVDNEGREVIHSGMTKMSKSKNNGIDPQLMVERYGADTVRLFMMFASPAEMTLEWSDSGVEGAQRF
LRRLWRITFEHVSAGVAPALNVAALSVDQKAVRRELHKTIAKVSDDVGRRQTFNTAIAAIMELMNNLAKLGSDEQDRALM
QEALEAVVVMLYPITPHIGFELWKMLGKGDDVDHATWPVADEAAMVETEKLVVVQINGKMRGKLTVPAEISQADVEKLAM
ADASVQKFTDGLTVRKVIYVPGKLLNIVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-159 42